BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 30273014)

  • 1. The development of protein tyrosine phosphatase1B inhibitors defined by binding sites in crystalline complexes.
    Zhang Y; Du Y
    Future Med Chem; 2018 Oct; 10(19):2345-2367. PubMed ID: 30273014
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity.
    Liu P; Du Y; Song L; Shen J; Li Q
    Eur J Med Chem; 2016 Aug; 118():27-33. PubMed ID: 27123900
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel, potent, selective and cellular active ABC type PTP1B inhibitors containing (methanesulfonyl-phenyl-amino)-acetic acid methyl ester phosphotyrosine mimetic.
    Liu P; Du Y; Song L; Shen J; Li Q
    Bioorg Med Chem; 2015 Nov; 23(21):7079-88. PubMed ID: 26481657
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The design strategy of selective PTP1B inhibitors over TCPTP.
    Li X; Wang L; Shi D
    Bioorg Med Chem; 2016 Aug; 24(16):3343-52. PubMed ID: 27353889
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of novel high potent and cellular active ADC type PTP1B inhibitors with selectivity over TC-PTP via modification interacting with C site.
    Du Y; Zhang Y; Ling H; Li Q; Shen J
    Eur J Med Chem; 2018 Jan; 144():692-700. PubMed ID: 29289892
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors.
    Zhang R; Yu R; Xu Q; Li X; Luo J; Jiang B; Wang L; Guo S; Wu N; Shi D
    Eur J Med Chem; 2017 Jul; 134():24-33. PubMed ID: 28395151
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Y-shaped bis-arylethenesulfonic acid esters: Potential potent and membrane permeable protein tyrosine phosphatase 1B inhibitors.
    Yang F; Xie F; Zhang Y; Xia Y; Liu W; Jiang F; Lam C; Qiao Y; Xie D; Li J; Fu L
    Bioorg Med Chem Lett; 2017 May; 27(10):2166-2170. PubMed ID: 28372909
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Diphenylether derivative as selective inhibitor of protein tyrosine phosphatase 1B (PTP1B) over t-cell protein tyrosine phosphatase (TCPTP) identified through virtual screening.
    Reddy MV; Ghadiyaram C; Panigrahi SK; Hosahalli S; Mangamoori LN
    Mini Rev Med Chem; 2013 Oct; 13(11):1602-6. PubMed ID: 24000798
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Investigation of selective binding of inhibitors to PTP1B and TCPTP by accelerated molecular dynamics simulations.
    Chen X; Gan Q; Feng C; Liu X; Zhang Q
    J Biomol Struct Dyn; 2019 Sep; 37(14):3697-3706. PubMed ID: 30238851
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, biological activity and structure-activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells.
    Ottanà R; Maccari R; Mortier J; Caselli A; Amuso S; Camici G; Rotondo A; Wolber G; Paoli P
    Eur J Med Chem; 2014 Jan; 71():112-27. PubMed ID: 24287560
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of novel, potent, selective and cellular active ADC type PTP1B inhibitors via fragment-docking-oriented de novel design.
    Du Y; Ling H; Zhang M; Shen J; Li Q
    Bioorg Med Chem; 2015 Aug; 23(15):4891-4898. PubMed ID: 26100442
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of 4,4-dimethyl lithocholic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B.
    He HB; Gao LX; Deng QF; Ma WP; Tang CL; Qiu WW; Tang J; Li JY; Li J; Yang F
    Bioorg Med Chem Lett; 2012 Dec; 22(23):7237-42. PubMed ID: 23067554
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PTP1b Inhibition, A Promising Approach for the Treatment of Diabetes Type II.
    Eleftheriou P; Geronikaki A; Petrou A
    Curr Top Med Chem; 2019; 19(4):246-263. PubMed ID: 30714526
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Recent Advances in Protein Tyrosine Phosphatase 1B Targeted Drug Discovery for Type II Diabetes and Obesity.
    Maheshwari N; Karthikeyan C; Trivedi P; Moorthy NSHN
    Curr Drug Targets; 2018; 19(5):551-575. PubMed ID: 28228082
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of 1,3-diphenyl-1H-pyrazole derivatives containing rhodanine-3-alkanoic acid groups as potential PTP1B inhibitors.
    Sun L; Wang P; Xu L; Gao L; Li J; Piao H
    Bioorg Med Chem Lett; 2019 May; 29(10):1187-1193. PubMed ID: 30910462
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of 2-ethoxy-4-(methoxymethyl)benzamide derivatives as potent and selective PTP1B inhibitors.
    Xie F; Liang Y; Xia Y; Luo S; Jiang F; Fu L
    Bioorg Chem; 2019 Nov; 92():103273. PubMed ID: 31539748
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design and synthesis of imidazolidine-2,4-dione derivatives as selective inhibitors by targeting protein tyrosine phosphatase-1B over T-cell protein tyrosine phosphatase.
    Ma Y; Sun SX; Cheng XC; Wang SQ; Dong WL; Wang RL; Xu WR
    Chem Biol Drug Des; 2013 Nov; 82(5):595-602. PubMed ID: 23848232
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Virtual Screening of Novel and Selective Inhibitors of Protein Tyrosine Phosphatase 1B over T-Cell Protein Tyrosine Phosphatase Using a Bidentate Inhibition Strategy.
    Chen X; Gan Q; Feng C; Liu X; Zhang Q
    J Chem Inf Model; 2018 Apr; 58(4):837-847. PubMed ID: 29608303
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity.
    Zhang L; Jiang CS; Gao LX; Gong JX; Wang ZH; Li JY; Li J; Li XW; Guo YW
    Bioorg Med Chem Lett; 2016 Feb; 26(3):778-781. PubMed ID: 26774579
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In silico structure-based design of a potent and selective small peptide inhibitor of protein tyrosine phosphatase 1B, a novel therapeutic target for obesity and type 2 diabetes mellitus: a computer modeling approach.
    Rao GS; Ramachandran MV; Bajaj JS
    J Biomol Struct Dyn; 2006 Feb; 23(4):377-84. PubMed ID: 16363874
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.