BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

265 related articles for article (PubMed ID: 30273442)

  • 1. Dual-specificity phosphatase 6 deletion protects the colonic epithelium against inflammation and promotes both proliferation and tumorigenesis.
    Beaudry K; Langlois MJ; Montagne A; Cagnol S; Carrier JC; Rivard N
    J Cell Physiol; 2019 May; 234(5):6731-6745. PubMed ID: 30273442
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The tyrosine phosphatase Shp-2 confers resistance to colonic inflammation by driving goblet cell function and crypt regeneration.
    Gagné-Sansfacon J; Langlois A; Langlois MJ; Coulombe G; Tremblay S; Vaillancourt-Lavigueur V; Qu CK; Menendez A; Rivard N
    J Pathol; 2019 Jan; 247(1):135-146. PubMed ID: 30376595
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice.
    Bertin S; Lozano-Ruiz B; Bachiller V; García-Martínez I; Herdman S; Zapater P; Francés R; Such J; Lee J; Raz E; González-Navajas JM
    Mucosal Immunol; 2015 May; 8(3):505-15. PubMed ID: 25227984
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility.
    Maillet M; Purcell NH; Sargent MA; York AJ; Bueno OF; Molkentin JD
    J Biol Chem; 2008 Nov; 283(45):31246-55. PubMed ID: 18753132
    [TBL] [Abstract][Full Text] [Related]  

  • 5. NHE8 Deficiency Promotes Colitis-Associated Cancer in Mice via Expansion of Lgr5-Expressing Cells.
    Xu H; Li J; Chen H; Ghishan FK
    Cell Mol Gastroenterol Hepatol; 2019; 7(1):19-31. PubMed ID: 30465020
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increased levels of DUSP6 phosphatase stimulate tumourigenesis in a molecularly distinct melanoma subtype.
    Li W; Song L; Ritchie AM; Melton DW
    Pigment Cell Melanoma Res; 2012 Mar; 25(2):188-99. PubMed ID: 22171919
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tumor suppressor dual-specificity phosphatase 6 (DUSP6) impairs cell invasion and epithelial-mesenchymal transition (EMT)-associated phenotype.
    Wong VC; Chen H; Ko JM; Chan KW; Chan YP; Law S; Chua D; Kwong DL; Lung HL; Srivastava G; Tang JC; Tsao SW; Zabarovsky ER; Stanbridge EJ; Lung ML
    Int J Cancer; 2012 Jan; 130(1):83-95. PubMed ID: 21387288
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Down-regulation of dual-specificity phosphatase 6, a negative regulator of oncogenic ERK signaling, by ACA-28 induces apoptosis in NIH/3T3 cells overexpressing HER2/ErbB2.
    Kanda Y; Mizuno A; Takasaki T; Satoh R; Hagihara K; Masuko T; Endo Y; Tanabe G; Sugiura R
    Genes Cells; 2021 Feb; 26(2):109-116. PubMed ID: 33249692
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice.
    Chang CS; Liao YC; Huang CT; Lin CM; Cheung CHY; Ruan JW; Yu WH; Tsai YT; Lin IJ; Huang CH; Liou JS; Chou YH; Chien HJ; Chuang HL; Juan HF; Huang HC; Chan HL; Liao YC; Tang SC; Su YW; Tan TH; Bäumler AJ; Kao CY
    Cell Rep; 2021 Nov; 37(8):110016. PubMed ID: 34818535
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MicroRNA 301A Promotes Intestinal Inflammation and Colitis-Associated Cancer Development by Inhibiting BTG1.
    He C; Yu T; Shi Y; Ma C; Yang W; Fang L; Sun M; Wu W; Xiao F; Guo F; Chen M; Yang H; Qian J; Cong Y; Liu Z
    Gastroenterology; 2017 May; 152(6):1434-1448.e15. PubMed ID: 28193514
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice.
    Zhao J; Bulek K; Gulen MF; Zepp JA; Karagkounis G; Martin BN; Zhou H; Yu M; Liu X; Huang E; Fox PL; Kalady MF; Markowitz SD; Li X
    Gastroenterology; 2015 Dec; 149(7):1860-1871.e8. PubMed ID: 26344057
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Serine-threonine Kinase Receptor-Associated Protein is a Critical Mediator of APC Mutation-Induced Intestinal Tumorigenesis Through a Feed-Forward Mechanism.
    Vu T; Datta A; Banister C; Jin L; Yuan G; Samuel T; Bae S; Eltoum IE; Manne U; Zhang B; Welner RS; Mitra K; Buckhaults P; Datta PK
    Gastroenterology; 2022 Jan; 162(1):193-208. PubMed ID: 34520730
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Post-transcriptional regulation of the DUSP6/MKP-3 phosphatase by MEK/ERK signaling and hypoxia.
    Bermudez O; Jouandin P; Rottier J; Bourcier C; Pagès G; Gimond C
    J Cell Physiol; 2011 Jan; 226(1):276-84. PubMed ID: 20665674
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dual-specificity phosphatase 6 plays a critical role in the maintenance of a cancer stem-like cell phenotype in human endometrial cancer.
    Kato M; Onoyama I; Yoshida S; Cui L; Kawamura K; Kodama K; Hori E; Matsumura Y; Yagi H; Asanoma K; Yahata H; Itakura A; Takeda S; Kato K
    Int J Cancer; 2020 Oct; 147(7):1987-1999. PubMed ID: 32159851
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis.
    Duan S; Moro L; Qu R; Simoneschi D; Cho H; Jiang S; Zhao H; Chang Q; de Stanchina E; Arbini AA; Pagano M
    Cell Rep; 2021 Oct; 37(3):109870. PubMed ID: 34686346
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Deletion of p38-alpha mitogen-activated protein kinase within the intestinal epithelium promotes colon tumorigenesis.
    Wakeman D; Schneider JE; Liu J; Wandu WS; Erwin CR; Guo J; Stappenbeck TS; Warner BW
    Surgery; 2012 Aug; 152(2):286-93. PubMed ID: 22828150
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DUSP10 regulates intestinal epithelial cell growth and colorectal tumorigenesis.
    Png CW; Weerasooriya M; Guo J; James SJ; Poh HM; Osato M; Flavell RA; Dong C; Yang H; Zhang Y
    Oncogene; 2016 Jan; 35(2):206-17. PubMed ID: 25772234
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-kappaB.
    Edelblum KL; Washington MK; Koyama T; Robine S; Baccarini M; Polk DB
    Gastroenterology; 2008 Aug; 135(2):539-51. PubMed ID: 18598699
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Short-Chain Fatty Acid Decreases the Expression of CEBPB to Inhibit miR-145-Mediated DUSP6 and Thus Further Suppresses Intestinal Inflammation.
    Liu Q; Peng Z; Zhou L; Peng R; Li X; Zuo W; Gou J; Zhou F; Yu S; Huang M; Liu H
    Inflammation; 2022 Feb; 45(1):372-386. PubMed ID: 34792688
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells.
    Zhang Z; Kobayashi S; Borczuk AC; Leidner RS; Laframboise T; Levine AD; Halmos B
    Carcinogenesis; 2010 Apr; 31(4):577-86. PubMed ID: 20097731
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.