260 related articles for article (PubMed ID: 30275013)
1. Synergistic effects of functionally distinct substitutions in β-lactamase variants shed light on the evolution of bacterial drug resistance.
Patel MP; Hu L; Brown CA; Sun Z; Adamski CJ; Stojanoski V; Sankaran B; Prasad BVV; Palzkill T
J Biol Chem; 2018 Nov; 293(46):17971-17984. PubMed ID: 30275013
[TBL] [Abstract][Full Text] [Related]
2. Antagonism between substitutions in β-lactamase explains a path not taken in the evolution of bacterial drug resistance.
Brown CA; Hu L; Sun Z; Patel MP; Singh S; Porter JR; Sankaran B; Prasad BVV; Bowman GR; Palzkill T
J Biol Chem; 2020 May; 295(21):7376-7390. PubMed ID: 32299911
[TBL] [Abstract][Full Text] [Related]
3. Mutational events in cefotaximase extended-spectrum beta-lactamases of the CTX-M-1 cluster involved in ceftazidime resistance.
Novais A; Cantón R; Coque TM; Moya A; Baquero F; Galán JC
Antimicrob Agents Chemother; 2008 Jul; 52(7):2377-82. PubMed ID: 18443114
[TBL] [Abstract][Full Text] [Related]
4. Molecular basis for the catalytic specificity of the CTX-M extended-spectrum β-lactamases.
Adamski CJ; Cardenas AM; Brown NG; Horton LB; Sankaran B; Prasad BV; Gilbert HF; Palzkill T
Biochemistry; 2015 Jan; 54(2):447-57. PubMed ID: 25489790
[TBL] [Abstract][Full Text] [Related]
5. The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M β-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation.
Patel MP; Hu L; Stojanoski V; Sankaran B; Prasad BVV; Palzkill T
Biochemistry; 2017 Jul; 56(27):3443-3453. PubMed ID: 28613873
[TBL] [Abstract][Full Text] [Related]
6. A novel extended-spectrum beta-lactamase CTX-M-23 with a P167T substitution in the active-site omega loop associated with ceftazidime resistance.
Stürenburg E; Kühn A; Mack D; Laufs R
J Antimicrob Chemother; 2004 Aug; 54(2):406-9. PubMed ID: 15201232
[TBL] [Abstract][Full Text] [Related]
7. Role of Asp104 in the SHV beta-lactamase.
Bethel CR; Hujer AM; Hujer KM; Thomson JM; Ruszczycky MW; Anderson VE; Pusztai-Carey M; Taracila M; Helfand MS; Bonomo RA
Antimicrob Agents Chemother; 2006 Dec; 50(12):4124-31. PubMed ID: 16982784
[TBL] [Abstract][Full Text] [Related]
8. A triple mutant in the Ω-loop of TEM-1 β-lactamase changes the substrate profile via a large conformational change and an altered general base for catalysis.
Stojanoski V; Chow DC; Hu L; Sankaran B; Gilbert HF; Prasad BV; Palzkill T
J Biol Chem; 2015 Apr; 290(16):10382-94. PubMed ID: 25713062
[TBL] [Abstract][Full Text] [Related]
9. Deciphering the Evolution of Cephalosporin Resistance to Ceftolozane-Tazobactam in Pseudomonas aeruginosa.
Barnes MD; Taracila MA; Rutter JD; Bethel CR; Galdadas I; Hujer AM; Caselli E; Prati F; Dekker JP; Papp-Wallace KM; Haider S; Bonomo RA
mBio; 2018 Dec; 9(6):. PubMed ID: 30538183
[No Abstract] [Full Text] [Related]
10. Construction and characterization of mutants of the TEM-1 beta-lactamase containing amino acid substitutions associated with both extended-spectrum resistance and resistance to beta-lactamase inhibitors.
Stapleton PD; Shannon KP; French GL
Antimicrob Agents Chemother; 1999 Aug; 43(8):1881-7. PubMed ID: 10428907
[TBL] [Abstract][Full Text] [Related]
11. Natural Variants of the KPC-2 Carbapenemase have Evolved Increased Catalytic Efficiency for Ceftazidime Hydrolysis at the Cost of Enzyme Stability.
Mehta SC; Rice K; Palzkill T
PLoS Pathog; 2015 Jun; 11(6):e1004949. PubMed ID: 26030609
[TBL] [Abstract][Full Text] [Related]
12. Dissemination of transferable CTX-M-type extended-spectrum beta-lactamase-producing Escherichia coli in Korea.
Jeong SH; Bae IK; Kwon SB; Lee JH; Song JS; Jung HI; Sung KH; Jang SJ; Lee SH
J Appl Microbiol; 2005; 98(4):921-7. PubMed ID: 15752339
[TBL] [Abstract][Full Text] [Related]
13. An active site loop toggles between conformations to control antibiotic hydrolysis and inhibition potency for CTX-M β-lactamase drug-resistance enzymes.
Lu S; Hu L; Lin H; Judge A; Rivera P; Palaniappan M; Sankaran B; Wang J; Prasad BVV; Palzkill T
Nat Commun; 2022 Nov; 13(1):6726. PubMed ID: 36344533
[TBL] [Abstract][Full Text] [Related]
14. Structural and Mechanistic Basis for Extended-Spectrum Drug-Resistance Mutations in Altering the Specificity of TEM, CTX-M, and KPC β-lactamases.
Palzkill T
Front Mol Biosci; 2018; 5():16. PubMed ID: 29527530
[TBL] [Abstract][Full Text] [Related]
15. Characterization of the global stabilizing substitution A77V and its role in the evolution of CTX-M β-lactamases.
Patel MP; Fryszczyn BG; Palzkill T
Antimicrob Agents Chemother; 2015 Nov; 59(11):6741-8. PubMed ID: 26282414
[TBL] [Abstract][Full Text] [Related]
16. Atomic resolution structures of CTX-M beta-lactamases: extended spectrum activities from increased mobility and decreased stability.
Chen Y; Delmas J; Sirot J; Shoichet B; Bonnet R
J Mol Biol; 2005 Apr; 348(2):349-62. PubMed ID: 15811373
[TBL] [Abstract][Full Text] [Related]
17. Natural variants modify Klebsiella pneumoniae carbapenemase (KPC) acyl-enzyme conformational dynamics to extend antibiotic resistance.
Tooke CL; Hinchliffe P; Bonomo RA; Schofield CJ; Mulholland AJ; Spencer J
J Biol Chem; 2021; 296():100126. PubMed ID: 33257320
[TBL] [Abstract][Full Text] [Related]
18.
Barnes MD; Winkler ML; Taracila MA; Page MG; Desarbre E; Kreiswirth BN; Shields RK; Nguyen MH; Clancy C; Spellberg B; Papp-Wallace KM; Bonomo RA
mBio; 2017 Oct; 8(5):. PubMed ID: 29089425
[TBL] [Abstract][Full Text] [Related]
19. Hydrolysis spectrum extension of CMY-2-like β-lactamases resulting from structural alteration in the Y-X-N loop.
Dahyot S; Mammeri H
Antimicrob Agents Chemother; 2012 Mar; 56(3):1151-6. PubMed ID: 22232281
[TBL] [Abstract][Full Text] [Related]
20. Novel cefotaximase (CTX-M-16) with increased catalytic efficiency due to substitution Asp-240-->Gly.
Bonnet R; Dutour C; Sampaio JL; Chanal C; Sirot D; Labia R; De Champs C; Sirot J
Antimicrob Agents Chemother; 2001 Aug; 45(8):2269-75. PubMed ID: 11451684
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
