BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

401 related articles for article (PubMed ID: 30275336)

  • 1. High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing.
    Sago CD; Lokugamage MP; Paunovska K; Vanover DA; Monaco CM; Shah NN; Gamboa Castro M; Anderson SE; Rudoltz TG; Lando GN; Munnilal Tiwari P; Kirschman JL; Willett N; Jang YC; Santangelo PJ; Bryksin AV; Dahlman JE
    Proc Natl Acad Sci U S A; 2018 Oct; 115(42):E9944-E9952. PubMed ID: 30275336
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA.
    Miller JB; Zhang S; Kos P; Xiong H; Zhou K; Perelman SS; Zhu H; Siegwart DJ
    Angew Chem Int Ed Engl; 2017 Jan; 56(4):1059-1063. PubMed ID: 27981708
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fast and Efficient CRISPR/Cas9 Genome Editing In Vivo Enabled by Bioreducible Lipid and Messenger RNA Nanoparticles.
    Liu J; Chang J; Jiang Y; Meng X; Sun T; Mao L; Xu Q; Wang M
    Adv Mater; 2019 Aug; 31(33):e1902575. PubMed ID: 31215123
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative analysis of lipid Nanoparticle-Mediated delivery of CRISPR-Cas9 RNP versus mRNA/sgRNA for gene editing in vitro and in vivo.
    Walther J; Porenta D; Wilbie D; Seinen C; Benne N; Yang Q; de Jong OG; Lei Z; Mastrobattista E
    Eur J Pharm Biopharm; 2024 Mar; 196():114207. PubMed ID: 38325664
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing.
    Finn JD; Smith AR; Patel MC; Shaw L; Youniss MR; van Heteren J; Dirstine T; Ciullo C; Lescarbeau R; Seitzer J; Shah RR; Shah A; Ling D; Growe J; Pink M; Rohde E; Wood KM; Salomon WE; Harrington WF; Dombrowski C; Strapps WR; Chang Y; Morrissey DV
    Cell Rep; 2018 Feb; 22(9):2227-2235. PubMed ID: 29490262
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High content analysis platform for optimization of lipid mediated CRISPR-Cas9 delivery strategies in human cells.
    Steyer B; Carlson-Stevermer J; Angenent-Mari N; Khalil A; Harkness T; Saha K
    Acta Biomater; 2016 Apr; 34():143-158. PubMed ID: 26747759
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nanoparticles That Deliver RNA to Bone Marrow Identified by in Vivo Directed Evolution.
    Sago CD; Lokugamage MP; Islam FZ; Krupczak BR; Sato M; Dahlman JE
    J Am Chem Soc; 2018 Dec; 140(49):17095-17105. PubMed ID: 30394729
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening.
    Guimaraes PPG; Zhang R; Spektor R; Tan M; Chung A; Billingsley MM; El-Mayta R; Riley RS; Wang L; Wilson JM; Mitchell MJ
    J Control Release; 2019 Dec; 316():404-417. PubMed ID: 31678653
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver.
    Sago CD; Lokugamage MP; Loughrey D; Lindsay KE; Hincapie R; Krupczak BR; Kalathoor S; Sato M; Echeverri ES; Fitzgerald JP; Gan Z; Gamboa L; Paunovska K; Sanhueza CA; Hatit MZC; Finn MG; Santangelo PJ; Dahlman JE
    Nat Biomed Eng; 2022 Feb; 6(2):157-167. PubMed ID: 35190679
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Analyzing 2000 in Vivo Drug Delivery Data Points Reveals Cholesterol Structure Impacts Nanoparticle Delivery.
    Paunovska K; Gil CJ; Lokugamage MP; Sago CD; Sato M; Lando GN; Gamboa Castro M; Bryksin AV; Dahlman JE
    ACS Nano; 2018 Aug; 12(8):8341-8349. PubMed ID: 30016076
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development of ionizable lipid nanoparticles and a lyophilized formulation for potent CRISPR-Cas9 delivery and genome editing.
    Sun Q; Zhang H; Ding F; Gao X; Zhu Z; Yang C
    Int J Pharm; 2024 Mar; 652():123845. PubMed ID: 38266942
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation.
    Paunovska K; Sago CD; Monaco CM; Hudson WH; Castro MG; Rudoltz TG; Kalathoor S; Vanover DA; Santangelo PJ; Ahmed R; Bryksin AV; Dahlman JE
    Nano Lett; 2018 Mar; 18(3):2148-2157. PubMed ID: 29489381
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of
    Qiu M; Glass Z; Chen J; Haas M; Jin X; Zhao X; Rui X; Ye Z; Li Y; Zhang F; Xu Q
    Proc Natl Acad Sci U S A; 2021 Mar; 118(10):. PubMed ID: 33649229
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Co-encapsulation of Cas9 mRNA and guide RNA in polyplex micelles enables genome editing in mouse brain.
    Abbasi S; Uchida S; Toh K; Tockary TA; Dirisala A; Hayashi K; Fukushima S; Kataoka K
    J Control Release; 2021 Apr; 332():260-268. PubMed ID: 33647431
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Constrained Nanoparticles Deliver siRNA and sgRNA to T Cells In Vivo without Targeting Ligands.
    Lokugamage MP; Sago CD; Gan Z; Krupczak BR; Dahlman JE
    Adv Mater; 2019 Oct; 31(41):e1902251. PubMed ID: 31465135
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Delivery Aspects of CRISPR/Cas for in Vivo Genome Editing.
    Wilbie D; Walther J; Mastrobattista E
    Acc Chem Res; 2019 Jun; 52(6):1555-1564. PubMed ID: 31099553
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intracellular Delivery of mRNA for Cell-Selective CRISPR/Cas9 Genome Editing using Lipid Nanoparticles.
    Ma T; Chen X; Wang M
    Chembiochem; 2023 May; 24(9):e202200801. PubMed ID: 36780174
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Robust genome editing in adult vascular endothelium by nanoparticle delivery of CRISPR-Cas9 plasmid DNA.
    Zhang X; Jin H; Huang X; Chaurasiya B; Dong D; Shanley TP; Zhao YY
    Cell Rep; 2022 Jan; 38(1):110196. PubMed ID: 34986352
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Developing Biodegradable Lipid Nanoparticles for Intracellular mRNA Delivery and Genome Editing.
    Qiu M; Li Y; Bloomer H; Xu Q
    Acc Chem Res; 2021 Nov; 54(21):4001-4011. PubMed ID: 34668716
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Postnatal Cardiac Gene Editing Using CRISPR/Cas9 With AAV9-Mediated Delivery of Short Guide RNAs Results in Mosaic Gene Disruption.
    Johansen AK; Molenaar B; Versteeg D; Leitoguinho AR; Demkes C; Spanjaard B; de Ruiter H; Akbari Moqadam F; Kooijman L; Zentilin L; Giacca M; van Rooij E
    Circ Res; 2017 Oct; 121(10):1168-1181. PubMed ID: 28851809
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.