BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

330 related articles for article (PubMed ID: 30279168)

  • 1. Soluble gp130 prevents interleukin-6 and interleukin-11 cluster signaling but not intracellular autocrine responses.
    Lamertz L; Rummel F; Polz R; Baran P; Hansen S; Waetzig GH; Moll JM; Floss DM; Scheller J
    Sci Signal; 2018 Oct; 11(550):. PubMed ID: 30279168
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alternative intronic polyadenylation generates the interleukin-6 trans-signaling inhibitor sgp130-E10.
    Sommer J; Garbers C; Wolf J; Trad A; Moll JM; Sack M; Fischer R; Grötzinger J; Waetzig GH; Floss DM; Scheller J
    J Biol Chem; 2014 Aug; 289(32):22140-50. PubMed ID: 24973212
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The balance of interleukin (IL)-6, IL-6·soluble IL-6 receptor (sIL-6R), and IL-6·sIL-6R·sgp130 complexes allows simultaneous classic and trans-signaling.
    Baran P; Hansen S; Waetzig GH; Akbarzadeh M; Lamertz L; Huber HJ; Ahmadian MR; Moll JM; Scheller J
    J Biol Chem; 2018 May; 293(18):6762-6775. PubMed ID: 29559558
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interleukin-6 and its receptors: a highly regulated and dynamic system.
    Wolf J; Rose-John S; Garbers C
    Cytokine; 2014 Nov; 70(1):11-20. PubMed ID: 24986424
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-guided optimization of the interleukin-6 trans-signaling antagonist sgp130.
    Tenhumberg S; Waetzig GH; Chalaris A; Rabe B; Seegert D; Scheller J; Rose-John S; Grötzinger J
    J Biol Chem; 2008 Oct; 283(40):27200-7. PubMed ID: 18650419
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Different Soluble Forms of the Interleukin-6 Family Signal Transducer gp130 Fine-tune the Blockade of Interleukin-6 Trans-signaling.
    Wolf J; Waetzig GH; Chalaris A; Reinheimer TM; Wege H; Rose-John S; Garbers C
    J Biol Chem; 2016 Jul; 291(31):16186-96. PubMed ID: 27226573
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer.
    Rose-John S; Scheller J; Elson G; Jones SA
    J Leukoc Biol; 2006 Aug; 80(2):227-36. PubMed ID: 16707558
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of classic signaling is a novel function of soluble glycoprotein 130 (sgp130), which is controlled by the ratio of interleukin 6 and soluble interleukin 6 receptor.
    Garbers C; Thaiss W; Jones GW; Waetzig GH; Lorenzen I; Guilhot F; Lissilaa R; Ferlin WG; Grötzinger J; Jones SA; Rose-John S; Scheller J
    J Biol Chem; 2011 Dec; 286(50):42959-70. PubMed ID: 21990364
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses.
    Jostock T; Müllberg J; Ozbek S; Atreya R; Blinn G; Voltz N; Fischer M; Neurath MF; Rose-John S
    Eur J Biochem; 2001 Jan; 268(1):160-7. PubMed ID: 11121117
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transcytosis of IL-11 and Apical Redirection of gp130 Is Mediated by IL-11α Receptor.
    Monhasery N; Moll J; Cuman C; Franke M; Lamertz L; Nitz R; Görg B; Häussinger D; Lokau J; Floss DM; Piekorz R; Dimitriadis E; Garbers C; Scheller J
    Cell Rep; 2016 Jul; 16(4):1067-1081. PubMed ID: 27425614
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of blockade of peripheral interleukin-6 trans-signaling on hippocampus-dependent and independent memory in mice.
    Braun O; Dewitz C; Möller-Hackbarth K; Scheller J; Schiffelholz T; Baier PC; Rose-John S
    J Interferon Cytokine Res; 2013 May; 33(5):254-60. PubMed ID: 23215755
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IL-6 trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6.
    Rose-John S
    Int J Biol Sci; 2012; 8(9):1237-47. PubMed ID: 23136552
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A soluble form of the interleukin-6 family signal transducer gp130 is dimerized via a C-terminal disulfide bridge resulting from alternative mRNA splicing.
    Wolf J; Waetzig GH; Reinheimer TM; Scheller J; Rose-John S; Garbers C
    Biochem Biophys Res Commun; 2016 Feb; 470(4):870-6. PubMed ID: 26809098
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Minimal interleukin 6 (IL-6) receptor stalk composition for IL-6 receptor shedding and IL-6 classic signaling.
    Baran P; Nitz R; Grötzinger J; Scheller J; Garbers C
    J Biol Chem; 2013 May; 288(21):14756-68. PubMed ID: 23564454
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interleukin-6 controls recycling and degradation, but not internalization of its receptors.
    Flynn CM; Kespohl B; Daunke T; Garbers Y; Düsterhöft S; Rose-John S; Haybaeck J; Lokau J; Aparicio-Siegmund S; Garbers C
    J Biol Chem; 2021; 296():100434. PubMed ID: 33610555
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The classic signalling and trans-signalling of interleukin-6 are both injurious in podocyte under high glucose exposure.
    Lei CT; Su H; Ye C; Tang H; Gao P; Wan C; He FF; Wang YM; Zhang C
    J Cell Mol Med; 2018 Jan; 22(1):251-260. PubMed ID: 28881473
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proteolytic control of Interleukin-11 and Interleukin-6 biology.
    Lokau J; Agthe M; Flynn CM; Garbers C
    Biochim Biophys Acta Mol Cell Res; 2017 Nov; 1864(11 Pt B):2105-2117. PubMed ID: 28630024
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel Insights into Interleukin 6 (IL-6) Cis- and Trans-signaling Pathways by Differentially Manipulating the Assembly of the IL-6 Signaling Complex.
    Lacroix M; Rousseau F; Guilhot F; Malinge P; Magistrelli G; Herren S; Jones SA; Jones GW; Scheller J; Lissilaa R; Kosco-Vilbois M; Johnson Z; Buatois V; Ferlin W
    J Biol Chem; 2015 Nov; 290(45):26943-26953. PubMed ID: 26363066
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions.
    Dahmen H; Horsten U; Küster A; Jacques Y; Minvielle S; Kerr IM; Ciliberto G; Paonessa G; Heinrich PC; Müller-Newen G
    Biochem J; 1998 May; 331 ( Pt 3)(Pt 3):695-702. PubMed ID: 9560294
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Soluble Interleukin 6 Receptor: Advanced Therapeutic Options in Inflammation.
    Rose-John S
    Clin Pharmacol Ther; 2017 Oct; 102(4):591-598. PubMed ID: 28675418
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.