BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 30279226)

  • 1. Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease.
    Paz K; Flynn R; Du J; Qi J; Luznik L; Maillard I; MacDonald KP; Hill GR; Serody JS; Murphy WJ; Sage PT; Sharpe AH; Miklos D; Cutler CS; Koreth J; Antin JH; Soiffer RJ; Ritz J; Bradner JE; Melnick AM; Blazar BR
    Blood; 2019 Jan; 133(1):94-99. PubMed ID: 30279226
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans.
    Flynn R; Du J; Veenstra RG; Reichenbach DK; Panoskaltsis-Mortari A; Taylor PA; Freeman GJ; Serody JS; Murphy WJ; Munn DH; Sarantopoulos S; Luznik L; Maillard I; Koreth J; Cutler C; Soiffer RJ; Antin JH; Ritz J; Dubovsky JA; Byrd JC; MacDonald KP; Hill GR; Blazar BR
    Blood; 2014 Jun; 123(25):3988-98. PubMed ID: 24820310
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease.
    Paz K; Flynn R; Du J; Tannheimer S; Johnson AJ; Dong S; Stark AK; Okkenhaug K; Panoskaltsis-Mortari A; Sage PT; Sharpe AH; Luznik L; Ritz J; Soiffer RJ; Cutler CS; Koreth J; Antin JH; Miklos DB; MacDonald KP; Hill GR; Maillard I; Serody JS; Murphy WJ; Munn DH; Feser C; Zaiken M; Vanhaesebroeck B; Turka LA; Byrd JC; Blazar BR
    Am J Transplant; 2019 Jun; 19(6):1820-1830. PubMed ID: 30748099
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Extrafollicular CD4
    Deng R; Hurtz C; Song Q; Yue C; Xiao G; Yu H; Wu X; Muschen M; Forman S; Martin PJ; Zeng D
    Nat Commun; 2017 Oct; 8(1):978. PubMed ID: 29042531
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aberrant germinal center formation, follicular T-helper cells, and germinal center B-cells were involved in chronic graft-versus-host disease.
    Shao L; Lie AK; Zhang Y; Wong CH; Kwong YL
    Ann Hematol; 2015 Sep; 94(9):1493-504. PubMed ID: 25963280
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cutting edge: T follicular helper cell differentiation is defective in the absence of Bcl6 BTB repressor domain function.
    Nance JP; Bélanger S; Johnston RJ; Takemori T; Crotty S
    J Immunol; 2015 Jun; 194(12):5599-603. PubMed ID: 25957170
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice.
    Wu Y; Schutt S; Paz K; Zhang M; Flynn RP; Bastian D; Sofi MH; Nguyen H; Dai M; Liu C; Chang YJ; Blazar BR; Yu XZ
    Blood; 2018 Apr; 131(17):1974-1986. PubMed ID: 29530952
    [TBL] [Abstract][Full Text] [Related]  

  • 8. IL-Y Aggravates Murine Chronic Graft-
    Wan L; Jin Z; Hu B; Lv K; Lei L; Liu Y; Song Y; Zhu Y; Gong H; Xu M; Du Y; Xu Y; Liu H; Wu D; Liu Y
    Front Immunol; 2020; 11():559740. PubMed ID: 33329519
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans.
    Srinivasan M; Flynn R; Price A; Ranger A; Browning JL; Taylor PA; Ritz J; Antin JH; Murphy WJ; Luznik L; Shlomchik MJ; Panoskaltsis-Mortari A; Blazar BR
    Blood; 2012 Feb; 119(6):1570-80. PubMed ID: 22072556
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BET-bromodomain and EZH2 inhibitor-treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes.
    Zaiken MC; Flynn R; Paz KG; Rhee SY; Jin S; Mohamed FA; Saha A; Thangavelu G; Park PMC; Hemming ML; Sage PT; Sharpe AH; DuPage M; Bluestone JA; Panoskaltsis-Mortari A; Cutler CS; Koreth J; Antin JH; Soiffer RJ; Ritz J; Luznik L; Maillard I; Hill GR; MacDonald KPA; Munn DH; Serody JS; Murphy WJ; Kean LS; Zhang Y; Bradner JE; Qi J; Blazar BR
    Blood; 2022 May; 139(19):2983-2997. PubMed ID: 35226736
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting Bcl-6 prevents sclerodermatous chronic graft-versus-host disease by abrogating T follicular helper differentiation in mice.
    Chen X; Wang Y; Huang X; Geng S; Li C; Zeng L; Huang L; Du X; Weng J; Lai P
    Int Immunopharmacol; 2023 Apr; 117():109746. PubMed ID: 36827923
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BCL6 BTB-specific inhibitor reversely represses T-cell activation, Tfh cells differentiation, and germinal center reaction in vivo.
    Cai Y; Poli ANR; Vadrevu S; Gyampoh K; Hart C; Ross B; Fair M; Xue F; Salvino JM; Montaner LJ
    Eur J Immunol; 2021 Oct; 51(10):2441-2451. PubMed ID: 34287839
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.
    Flynn R; Paz K; Du J; Reichenbach DK; Taylor PA; Panoskaltsis-Mortari A; Vulic A; Luznik L; MacDonald KK; Hill GR; Nyuydzefe MS; Weiss JM; Chen W; Trzeciak A; Serody JS; Aguilar EG; Murphy WJ; Maillard I; Munn D; Koreth J; Cutler CS; Antin JH; Ritz J; Waksal SD; Zanin-Zhorov A; Blazar BR
    Blood; 2016 Apr; 127(17):2144-54. PubMed ID: 26983850
    [TBL] [Abstract][Full Text] [Related]  

  • 14. C5aR1 regulates T follicular helper differentiation and chronic graft-versus-host disease bronchiolitis obliterans.
    Verghese DA; Chun N; Paz K; Fribourg M; Woodruff TM; Flynn R; Hu Y; Xiong H; Zhang W; Yi Z; Du J; Blazar BR; Heeger PS
    JCI Insight; 2018 Dec; 3(24):. PubMed ID: 30568034
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease.
    Flynn R; Allen JL; Luznik L; MacDonald KP; Paz K; Alexander KA; Vulic A; Du J; Panoskaltsis-Mortari A; Taylor PA; Poe JC; Serody JS; Murphy WJ; Hill GR; Maillard I; Koreth J; Cutler CS; Soiffer RJ; Antin JH; Ritz J; Chao NJ; Clynes RA; Sarantopoulos S; Blazar BR
    Blood; 2015 Jun; 125(26):4085-94. PubMed ID: 25852057
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production.
    Du J; Paz K; Flynn R; Vulic A; Robinson TM; Lineburg KE; Alexander KA; Meng J; Roy S; Panoskaltsis-Mortari A; Loschi M; Hill GR; Serody JS; Maillard I; Miklos D; Koreth J; Cutler CS; Antin JH; Ritz J; MacDonald KP; Schacker TW; Luznik L; Blazar BR
    Blood; 2017 May; 129(18):2570-2580. PubMed ID: 28254742
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice.
    Radojcic V; Paz K; Chung J; Du J; Perkey ET; Flynn R; Ivcevic S; Zaiken M; Friedman A; Yan M; Pletneva MA; Sarantopoulos S; Siebel CW; Blazar BR; Maillard I
    Blood; 2018 Nov; 132(20):2188-2200. PubMed ID: 30181175
    [TBL] [Abstract][Full Text] [Related]  

  • 18. T Follicular Helper Cell-Germinal Center B Cell Interaction Strength Regulates Entry into Plasma Cell or Recycling Germinal Center Cell Fate.
    Ise W; Fujii K; Shiroguchi K; Ito A; Kometani K; Takeda K; Kawakami E; Yamashita K; Suzuki K; Okada T; Kurosaki T
    Immunity; 2018 Apr; 48(4):702-715.e4. PubMed ID: 29669250
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Impaired bone marrow B-cell development in mice with a bronchiolitis obliterans model of cGVHD.
    Kolupaev OV; Dant TA; Bommiasamy H; Bruce DW; Fowler KA; Tilley SL; McKinnon KP; Sarantopoulos S; Blazar BR; Coghill JM; Serody JS
    Blood Adv; 2018 Sep; 2(18):2307-2319. PubMed ID: 30228128
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation.
    Vacchio MS; Ciucci T; Gao Y; Watanabe M; Balmaceno-Criss M; McGinty MT; Huang A; Xiao Q; McConkey C; Zhao Y; Shetty J; Tran B; Pepper M; Vahedi G; Jenkins MK; McGavern DB; Bosselut R
    Immunity; 2019 Sep; 51(3):465-478.e6. PubMed ID: 31422869
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.