BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 30279315)

  • 1. Crystal structure of mutant carboxypeptidase T from Thermoactinomyces vulgaris with an implanted S1' subsite from pancreatic carboxypeptidase B.
    Akparov VK; Timofeev VI; Kuranova IP; Rakitina TV
    Acta Crystallogr F Struct Biol Commun; 2018 Oct; 74(Pt 10):638-643. PubMed ID: 30279315
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mobile Loop in the Active Site of Metallocarboxypeptidases as an Underestimated Determinant of Substrate Specificity.
    Akparov VK; Timofeev VI; Khaliullin IG; Konstantinova GE; Kuranova IP; Rakitina TV; Švedas VK
    Biochemistry (Mosc); 2018 Dec; 83(12):1594-1602. PubMed ID: 30878033
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural principles of the broad substrate specificity of Thermoactinomyces vulgaris carboxypeptidase T--role of amino acid residues at positions 260 and 262.
    Grishin AM; Akparov VKh; Chestukhina GG
    Protein Eng Des Sel; 2008 Sep; 21(9):545-51. PubMed ID: 18515300
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural insights into the broad substrate specificity of carboxypeptidase T from Thermoactinomyces vulgaris.
    Akparov VKh; Timofeev VI; Khaliullin IG; Švedas V; Chestukhina GG; Kuranova IP
    FEBS J; 2015 Apr; 282(7):1214-24. PubMed ID: 25619204
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Three-dimensional structure of carboxypeptidase T from Thermoactinomyces vulgaris in complex with N-BOC-L-leucine.
    Timofeev VI; Kuznetsov SA; Akparov VKh; Chestukhina GG; Kuranova IP
    Biochemistry (Mosc); 2013 Mar; 78(3):252-9. PubMed ID: 23586718
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structures of carboxypeptidase T complexes with transition-state analogs.
    Akparov VK; Timofeev VI; Khaliullin IG; Švedas V; Kuranova IP; Rakitina TV
    J Biomol Struct Dyn; 2018 Nov; 36(15):3958-3966. PubMed ID: 29129130
    [No Abstract]   [Full Text] [Related]  

  • 7. [Characterization of S1' subsite specificity of Thermoactinomyces vulgaris carboxypeptidase T by site-directed mutagenesis].
    Trachuk LA; Bushueva AM; Shevelev AB; Novgorodova SA; Akparov VKh; Chestukhina GG
    Vopr Med Khim; 2002; 48(6):577-85. PubMed ID: 12698557
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The nature of the ligand's side chain interacting with the S1'-subsite of metallocarboxypeptidase T (from Thermoactinomyces vulgaris) determines the geometry of the tetrahedral transition complex.
    Akparov VK; Timofeev VI; Konstantinova GE; Khaliullin IG; Kuranova IP; Rakitina TV; Švedas V
    PLoS One; 2019; 14(12):e0226636. PubMed ID: 31887148
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural principles of the wide substrate specificity of Thermoactinomyces vulgaris carboxypeptidase T. Reconstruction of the carboxypeptidase B primary specificity pocket.
    Akparov VKh; Grishin AM; Yusupova MP; Ivanova NM; Chestukhina GG
    Biochemistry (Mosc); 2007 Apr; 72(4):416-23. PubMed ID: 17511606
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of the microbial carboxypeptidase T complexed with the transition state analog N-sulfamoyl-l-lysine.
    Akparov VK; Konstantinova GE; Timofeev VI; Khaliullin IG; Kuranova IP
    Biophys Chem; 2021 Mar; 270():106535. PubMed ID: 33412495
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Active site gate of M32 carboxypeptidases illuminated by crystal structure and molecular dynamics simulations.
    Sharma B; Jamdar SN; Ghosh B; Yadav P; Kumar A; Kundu S; Goyal VD; Makde RD
    Biochim Biophys Acta Proteins Proteom; 2017 Nov; 1865(11 Pt A):1406-1415. PubMed ID: 28844748
    [TBL] [Abstract][Full Text] [Related]  

  • 12. High-resolution structure of the M14-type cytosolic carboxypeptidase from Burkholderia cenocepacia refined exploiting PDB_REDO strategies.
    Rimsa V; Eadsforth TC; Joosten RP; Hunter WN
    Acta Crystallogr D Biol Crystallogr; 2014 Feb; 70(Pt 2):279-89. PubMed ID: 24531462
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure of Aedes aegypti carboxypeptidase B1-inhibitor complex uncover the disparity between mosquito and non-mosquito insect carboxypeptidase inhibition mechanism.
    Gavor E; Choong YK; Jobichen C; Mok YK; Kini RM; Sivaraman J
    Protein Sci; 2021 Dec; 30(12):2445-2456. PubMed ID: 34658092
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure of the carboxypeptidase B complex with N-sulfamoyl-L-phenylalanine - a transition state analog of non-specific substrate.
    Akparov V; Timofeev V; Khaliullin I; Švedas V; Kuranova I
    J Biomol Struct Dyn; 2018 Mar; 36(4):956-965. PubMed ID: 28274181
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Leu254 residue and calcium ions as new structural determinants of carboxypeptidase T substrate specificity.
    Grishin AM; Akparov VKh; Chestukhina GG
    Biochemistry (Mosc); 2008 Oct; 73(10):1140-5. PubMed ID: 18991561
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparative modeling of substrate binding in the S1' subsite of serine carboxypeptidases from yeast, wheat, and human.
    Elsliger MA; Pshezhetsky AV; Vinogradova MV; Svedas VK; Potier M
    Biochemistry; 1996 Nov; 35(47):14899-909. PubMed ID: 8942654
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Primary structure of carboxypeptidase T: delineation of functionally relevant features in Zn-carboxypeptidase family.
    Osterman AL; Grishin NV; Smulevitch SV; Matz MV; Zagnitko OP; Revina LP; Stepanov VM
    J Protein Chem; 1992 Oct; 11(5):561-70. PubMed ID: 1449602
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure and mechanism of human carboxypeptidase O: Insights into its specific activity for acidic residues.
    Garcia-Guerrero MC; Garcia-Pardo J; Berenguer E; Fernandez-Alvarez R; Barfi GB; Lyons PJ; Aviles FX; Huber R; Lorenzo J; Reverter D
    Proc Natl Acad Sci U S A; 2018 Apr; 115(17):E3932-E3939. PubMed ID: 29636417
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of carboxypeptidase T from Thermoactinomyces vulgaris.
    Teplyakov A; Polyakov K; Obmolova G; Strokopytov B; Kuranova I; Osterman A; Grishin N; Smulevitch S; Zagnitko O; Galperina O
    Eur J Biochem; 1992 Sep; 208(2):281-8. PubMed ID: 1521526
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Homology modeling of gelatinase catalytic domains and docking simulations of novel sulfonamide inhibitors.
    Kiyama R; Tamura Y; Watanabe F; Tsuzuki H; Ohtani M; Yodo M
    J Med Chem; 1999 May; 42(10):1723-38. PubMed ID: 10346925
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.