150 related articles for article (PubMed ID: 30280322)
1. Interactions of cantharidin-like inhibitors with human protein phosphatase-5 in a Mg
Assis LC; de Castro AA; Prandi IG; Mancini DT; de Giacoppo JOS; Savedra RML; de Assis TM; Carregal JB; da Cunha EFF; Ramalho TC
J Mol Model; 2018 Oct; 24(10):303. PubMed ID: 30280322
[TBL] [Abstract][Full Text] [Related]
2. Insights into the key interactions between human protein phosphatase 5 and cantharidin using molecular dynamics and site-directed mutagenesis bioassays.
Liu JY; Chen XE; Zhang YL
Sci Rep; 2015 Jul; 5():12359. PubMed ID: 26190207
[TBL] [Abstract][Full Text] [Related]
3. Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C.
Chattopadhyay D; Swingle MR; Salter EA; Wood E; D'Arcy B; Zivanov C; Abney K; Musiyenko A; Rusin SF; Kettenbach A; Yet L; Schroeder CE; Golden JE; Dunham WH; Gingras AC; Banerjee S; Forbes D; Wierzbicki A; Honkanen RE
Biochem Pharmacol; 2016 Jun; 109():14-26. PubMed ID: 27002182
[TBL] [Abstract][Full Text] [Related]
4. Ro 90-7501 inhibits PP5 through a novel, TPR-dependent mechanism.
Hong TJ; Park K; Choi EW; Hahn JS
Biochem Biophys Res Commun; 2017 Jan; 482(2):215-220. PubMed ID: 27840051
[TBL] [Abstract][Full Text] [Related]
5. Cantharidin impedes the activity of protein serine/threonine phosphatase in Plutella xylostella.
Chen X; Liu J; Zhang Y
Mol Biosyst; 2014 Feb; 10(2):240-50. PubMed ID: 24253262
[TBL] [Abstract][Full Text] [Related]
6. Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin.
Bertini I; Calderone V; Fragai M; Luchinat C; Talluri E
J Med Chem; 2009 Aug; 52(15):4838-43. PubMed ID: 19601647
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of protein phosphatase 5 suppresses non-small cell lung cancer through AMP-activated kinase activation.
Hsieh FS; Hung MH; Wang CY; Chen YL; Hsiao YJ; Tsai MH; Li JR; Chen LJ; Shih CT; Chao TI; Chen KF
Lung Cancer; 2017 Oct; 112():81-89. PubMed ID: 29191605
[TBL] [Abstract][Full Text] [Related]
8. Exploring the role of active site Mn
Wang L; Yan F
Biochem Biophys Res Commun; 2019 Apr; 511(3):612-618. PubMed ID: 30826056
[TBL] [Abstract][Full Text] [Related]
9. Development and validation of a robust and sensitive assay for the discovery of selective inhibitors for serine/threonine protein phosphatases PP1α (PPP1C) and PP5 (PPP5C).
Swingle MR; Honkanen RE
Assay Drug Dev Technol; 2014 Oct; 12(8):481-96. PubMed ID: 25383722
[TBL] [Abstract][Full Text] [Related]
10. Serine/threonine protein phosphatase 5 is a potential therapeutic target in cholangiocarcinoma.
Hu MH; Huang TT; Chao TI; Chen LJ; Chen YL; Tsai MH; Liu CY; Kao JH; Chen KF
Liver Int; 2018 Dec; 38(12):2248-2259. PubMed ID: 29797403
[TBL] [Abstract][Full Text] [Related]
11. Exploration of new drug-like inhibitors for serine/threonine protein phosphatase 5 of Plasmodium falciparum: a docking and simulation study.
Gupta S; Jadaun A; Kumar H; Raj U; Varadwaj PK; Rao AR
J Biomol Struct Dyn; 2015; 33(11):2421-41. PubMed ID: 25967133
[TBL] [Abstract][Full Text] [Related]
12. Anhydride modified cantharidin analogues. Is ring opening important in the inhibition of protein phosphatase 2A?
McCuskey A; Keane MA; Mudgee LM; Sim AT; Sakoff J; Quinn RJ
Eur J Med Chem; 2000 Oct; 35(10):957-64. PubMed ID: 11121622
[TBL] [Abstract][Full Text] [Related]
13. Deprotonation states of the two active site water molecules regulate the binding of protein phosphatase 5 with its substrate: A molecular dynamics study.
Wang L; Yan F
Protein Sci; 2017 Oct; 26(10):2010-2020. PubMed ID: 28726316
[TBL] [Abstract][Full Text] [Related]
14. Cytotoxicity of cantharidin analogues targeting protein phosphatase 2A.
Shan HB; Cai YC; Liu Y; Zeng WN; Chen HX; Fan BT; Liu XH; Xu ZL; Wang B; Xian LJ
Anticancer Drugs; 2006 Sep; 17(8):905-11. PubMed ID: 16940800
[TBL] [Abstract][Full Text] [Related]
15. Protein phosphatase 5 promotes hepatocarcinogenesis through interaction with AMP-activated protein kinase.
Chen YL; Hung MH; Chu PY; Chao TI; Tsai MH; Chen LJ; Hsiao YJ; Shih CT; Hsieh FS; Chen KF
Biochem Pharmacol; 2017 Aug; 138():49-60. PubMed ID: 28528695
[TBL] [Abstract][Full Text] [Related]
16. Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A.
Honkanen RE
FEBS Lett; 1993 Sep; 330(3):283-6. PubMed ID: 8397101
[TBL] [Abstract][Full Text] [Related]
17. Identification and biochemical characterization of protein phosphatase 5 from the cantharidin-producing blister beetle, Epicauta chinensis.
Chen X; Lü S; Zhang Y
Int J Mol Sci; 2013 Dec; 14(12):24501-13. PubMed ID: 24351830
[TBL] [Abstract][Full Text] [Related]
18. Cantharimides: a new class of modified cantharidin analogues inhibiting protein phosphatases 1 and 2A.
McCluskey A; Walkom C; Bowyer MC; Ackland SP; Gardiner E; Sakoff JA
Bioorg Med Chem Lett; 2001 Nov; 11(22):2941-6. PubMed ID: 11677131
[TBL] [Abstract][Full Text] [Related]
19. The inhibition of protein phosphatases 1 and 2A: a new target for rational anti-cancer drug design?
McCluskey A; Ackland SP; Gardiner E; Walkom CC; Sakoff JA
Anticancer Drug Des; 2001 Dec; 16(6):291-303. PubMed ID: 12375882
[TBL] [Abstract][Full Text] [Related]
20. Antitumor potential of the protein phosphatase inhibitor, cantharidin, and selected derivatives.
Ren Y; Kinghorn AD
Bioorg Med Chem; 2021 Feb; 32():116012. PubMed ID: 33454654
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
