217 related articles for article (PubMed ID: 30282318)
1. Synthesis and structure-activity relationship studies of cruzain and rhodesain inhibitors.
Rocha DA; Silva EB; Fortes IS; Lopes MS; Ferreira RS; Andrade SF
Eur J Med Chem; 2018 Sep; 157():1426-1459. PubMed ID: 30282318
[TBL] [Abstract][Full Text] [Related]
2. Cruzain and Rhodesain Inhibitors: Last Decade of Advances in Seeking for New Compounds Against American and African Trypanosomiases.
Dos Santos Nascimento IJ; de Aquino TM; da Silva-Júnior EF
Curr Top Med Chem; 2021; 21(21):1871-1899. PubMed ID: 33797369
[TBL] [Abstract][Full Text] [Related]
3. Development of alpha-keto-based inhibitors of cruzain, a cysteine protease implicated in Chagas disease.
Choe Y; Brinen LS; Price MS; Engel JC; Lange M; Grisostomi C; Weston SG; Pallai PV; Cheng H; Hardy LW; Hartsough DS; McMakin M; Tilton RF; Baldino CM; Craik CS
Bioorg Med Chem; 2005 Mar; 13(6):2141-56. PubMed ID: 15727867
[TBL] [Abstract][Full Text] [Related]
4. The Inhibition of Cysteine Proteases Rhodesain and TbCatB: A Valuable Approach to Treat Human African Trypanosomiasis.
Ettari R; Previti S; Tamborini L; Cullia G; Grasso S; Zappalà M
Mini Rev Med Chem; 2016; 16(17):1374-1391. PubMed ID: 27156518
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1.
Fonseca NC; da Cruz LF; da Silva Villela F; do Nascimento Pereira GA; de Siqueira-Neto JL; Kellar D; Suzuki BM; Ray D; de Souza TB; Alves RJ; Sales Júnior PA; Romanha AJ; Murta SM; McKerrow JH; Caffrey CR; de Oliveira RB; Ferreira RS
Antimicrob Agents Chemother; 2015 May; 59(5):2666-77. PubMed ID: 25712353
[TBL] [Abstract][Full Text] [Related]
6. Synthesis of macrocyclic trypanosomal cysteine protease inhibitors.
Chen YT; Lira R; Hansell E; McKerrow JH; Roush WR
Bioorg Med Chem Lett; 2008 Nov; 18(22):5860-3. PubMed ID: 18585034
[TBL] [Abstract][Full Text] [Related]
7. In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi.
Chen YT; Brinen LS; Kerr ID; Hansell E; Doyle PS; McKerrow JH; Roush WR
PLoS Negl Trop Dis; 2010 Sep; 4(9):. PubMed ID: 20856868
[TBL] [Abstract][Full Text] [Related]
8. Peptidyl allyl sulfones: a new class of inhibitors for clan CA cysteine proteases.
Götz MG; Caffrey CR; Hansell E; McKerrow JH; Powers JC
Bioorg Med Chem; 2004 Oct; 12(19):5203-11. PubMed ID: 15351403
[TBL] [Abstract][Full Text] [Related]
9. Targeting cysteine proteases in trypanosomatid disease drug discovery.
Ferreira LG; Andricopulo AD
Pharmacol Ther; 2017 Dec; 180():49-61. PubMed ID: 28579388
[TBL] [Abstract][Full Text] [Related]
10. A structure-based virtual high-throughput screening, molecular docking, molecular dynamics and MM/PBSA study identified novel putative drug-like dual inhibitors of trypanosomal cruzain and rhodesain cysteine proteases.
Eurtivong C; Zimmer C; Schirmeister T; Butkinaree C; Saruengkhanphasit R; Niwetmarin W; Ruchirawat S; Bhambra AS
Mol Divers; 2024 Apr; 28(2):531-551. PubMed ID: 36617352
[TBL] [Abstract][Full Text] [Related]
11. Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB.
Mott BT; Ferreira RS; Simeonov A; Jadhav A; Ang KK; Leister W; Shen M; Silveira JT; Doyle PS; Arkin MR; McKerrow JH; Inglese J; Austin CP; Thomas CJ; Shoichet BK; Maloney DJ
J Med Chem; 2010 Jan; 53(1):52-60. PubMed ID: 19908842
[TBL] [Abstract][Full Text] [Related]
12. Benzimidazole inhibitors of the major cysteine protease of
Pereira GA; Santos LH; Wang SC; Martins LC; Villela FS; Liao W; Dessoy MA; Dias LC; Andricopulo AD; Costa MA; Nagem RA; Caffrey CR; Liedl KR; Caffarena ER; Ferreira RS
Future Med Chem; 2019 Jul; 11(13):1537-1551. PubMed ID: 31469332
[No Abstract] [Full Text] [Related]
13. Inhibition of rhodesain as a novel therapeutic modality for human African trypanosomiasis.
Ettari R; Tamborini L; Angelo IC; Micale N; Pinto A; De Micheli C; Conti P
J Med Chem; 2013 Jul; 56(14):5637-58. PubMed ID: 23611656
[TBL] [Abstract][Full Text] [Related]
14. Vinyl sulfone-based inhibitors of trypanosomal cysteine protease rhodesain with improved antitrypanosomal activities.
Zhang H; Collins J; Nyamwihura R; Crown O; Ajayi O; Ogungbe IV
Bioorg Med Chem Lett; 2020 Jul; 30(14):127217. PubMed ID: 32527539
[TBL] [Abstract][Full Text] [Related]
15. Identification of a new class of nonpeptidic inhibitors of cruzain.
Brak K; Doyle PS; McKerrow JH; Ellman JA
J Am Chem Soc; 2008 May; 130(20):6404-10. PubMed ID: 18435536
[TBL] [Abstract][Full Text] [Related]
16. Computer-aided design of 1,4-naphthoquinone-based inhibitors targeting cruzain and rhodesain cysteine proteases.
Silva LR; Guimarães AS; do Nascimento J; do Santos Nascimento IJ; da Silva EB; McKerrow JH; Cardoso SH; da Silva-Júnior EF
Bioorg Med Chem; 2021 Jul; 41():116213. PubMed ID: 33992862
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of potential inhibitors of the cysteine proteases cruzain and rhodesain designed by molecular simplification.
Braga SF; Martins LC; da Silva EB; Sales Júnior PA; Murta SM; Romanha AJ; Soh WT; Brandstetter H; Ferreira RS; de Oliveira RB
Bioorg Med Chem; 2017 Mar; 25(6):1889-1900. PubMed ID: 28215783
[TBL] [Abstract][Full Text] [Related]
18. Vinyl sulfones as antiparasitic agents and a structural basis for drug design.
Kerr ID; Lee JH; Farady CJ; Marion R; Rickert M; Sajid M; Pandey KC; Caffrey CR; Legac J; Hansell E; McKerrow JH; Craik CS; Rosenthal PJ; Brinen LS
J Biol Chem; 2009 Sep; 284(38):25697-703. PubMed ID: 19620707
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents.
Yang PY; Wang M; Li L; Wu H; He CY; Yao SQ
Chemistry; 2012 May; 18(21):6528-41. PubMed ID: 22488888
[TBL] [Abstract][Full Text] [Related]
20. Molecular modeling and structure-activity relationships for a series of benzimidazole derivatives as cruzain inhibitors.
Pauli I; Ferreira LG; de Souza ML; Oliva G; Ferreira RS; Dessoy MA; Slafer BW; Dias LC; Andricopulo AD
Future Med Chem; 2017 May; 9(7):641-657. PubMed ID: 28509592
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]