These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
241 related articles for article (PubMed ID: 30283032)
1. Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden. Haure-Mirande JV; Wang M; Audrain M; Fanutza T; Kim SH; Heja S; Readhead B; Dudley JT; Blitzer RD; Schadt EE; Zhang B; Gandy S; Ehrlich ME Mol Psychiatry; 2019 Mar; 24(3):431-446. PubMed ID: 30283032 [TBL] [Abstract][Full Text] [Related]
2. Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology. Haure-Mirande JV; Audrain M; Fanutza T; Kim SH; Klein WL; Glabe C; Readhead B; Dudley JT; Blitzer RD; Wang M; Zhang B; Schadt EE; Gandy S; Ehrlich ME Acta Neuropathol; 2017 Nov; 134(5):769-788. PubMed ID: 28612290 [TBL] [Abstract][Full Text] [Related]
3. Microglial TYROBP/DAP12 in Alzheimer's disease: Transduction of physiological and pathological signals across TREM2. Haure-Mirande JV; Audrain M; Ehrlich ME; Gandy S Mol Neurodegener; 2022 Aug; 17(1):55. PubMed ID: 36002854 [TBL] [Abstract][Full Text] [Related]
4. Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau. Audrain M; Haure-Mirande JV; Wang M; Kim SH; Fanutza T; Chakrabarty P; Fraser P; St George-Hyslop PH; Golde TE; Blitzer RD; Schadt EE; Zhang B; Ehrlich ME; Gandy S Mol Psychiatry; 2019 Sep; 24(9):1383-1397. PubMed ID: 30283031 [TBL] [Abstract][Full Text] [Related]
5. Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP-APOE link in wild-type and Alzheimer's-related mice. Audrain M; Haure-Mirande JV; Mleczko J; Wang M; Griffin JK; St George-Hyslop PH; Fraser P; Zhang B; Gandy S; Ehrlich ME Alzheimers Dement; 2021 Feb; 17(2):149-163. PubMed ID: 33314529 [TBL] [Abstract][Full Text] [Related]
6. Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aβ42, Tau, TREM2, and TYROBP in Drosophila models. Sekiya M; Wang M; Fujisaki N; Sakakibara Y; Quan X; Ehrlich ME; De Jager PL; Bennett DA; Schadt EE; Gandy S; Ando K; Zhang B; Iijima KM Genome Med; 2018 Mar; 10(1):26. PubMed ID: 29598827 [TBL] [Abstract][Full Text] [Related]
7. Molecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(Δexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology. Readhead B; Haure-Mirande JV; Zhang B; Haroutunian V; Gandy S; Schadt EE; Dudley JT; Ehrlich ME Mol Psychiatry; 2016 Aug; 21(8):1099-111. PubMed ID: 26552589 [TBL] [Abstract][Full Text] [Related]
8. Human Alzheimer's disease gene expression signatures and immune profile in APP mouse models: a discrete transcriptomic view of Aβ plaque pathology. Rothman SM; Tanis KQ; Gandhi P; Malkov V; Marcus J; Pearson M; Stevens R; Gilliland J; Ware C; Mahadomrongkul V; O'Loughlin E; Zeballos G; Smith R; Howell BJ; Klappenbach J; Kennedy M; Mirescu C J Neuroinflammation; 2018 Sep; 15(1):256. PubMed ID: 30189875 [TBL] [Abstract][Full Text] [Related]
9. Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia. Xia D; Lianoglou S; Sandmann T; Calvert M; Suh JH; Thomsen E; Dugas J; Pizzo ME; DeVos SL; Earr TK; Lin CC; Davis S; Ha C; Leung AW; Nguyen H; Chau R; Yulyaningsih E; Lopez I; Solanoy H; Masoud ST; Liang CC; Lin K; Astarita G; Khoury N; Zuchero JY; Thorne RG; Shen K; Miller S; Palop JJ; Garceau D; Sasner M; Whitesell JD; Harris JA; Hummel S; Gnörich J; Wind K; Kunze L; Zatcepin A; Brendel M; Willem M; Haass C; Barnett D; Zimmer TS; Orr AG; Scearce-Levie K; Lewcock JW; Di Paolo G; Sanchez PE Mol Neurodegener; 2022 Jun; 17(1):41. PubMed ID: 35690868 [TBL] [Abstract][Full Text] [Related]
10. Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network. Takahashi H; Klein ZA; Bhagat SM; Kaufman AC; Kostylev MA; Ikezu T; Strittmatter SM; Acta Neuropathol; 2017 May; 133(5):785-807. PubMed ID: 28070672 [TBL] [Abstract][Full Text] [Related]
11. Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways. Ibanez KR; McFarland KN; Phillips J; Allen M; Lessard CB; Zobel L; De La Cruz EG; Shah S; Vo Q; Wang X; Quicksall Z; Ryu D; Funk C; Ertekin-Taner N; Prokop S; Golde TE; Chakrabarty P Alzheimers Res Ther; 2022 Jul; 14(1):104. PubMed ID: 35897046 [TBL] [Abstract][Full Text] [Related]
12. Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-β Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer's Disease: A Targeted Transcriptome Analysis. Ma C; Hunt JB; Kovalenko A; Liang H; Selenica MB; Orr MB; Zhang B; Gensel JC; Feola DJ; Gordon MN; Morgan D; Bickford PC; Lee DC Front Immunol; 2021; 12():628156. PubMed ID: 34046031 [TBL] [Abstract][Full Text] [Related]
13. Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease. Dodson SE; Andersen OM; Karmali V; Fritz JJ; Cheng D; Peng J; Levey AI; Willnow TE; Lah JJ J Neurosci; 2008 Nov; 28(48):12877-86. PubMed ID: 19036982 [TBL] [Abstract][Full Text] [Related]
14. Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model. Meilandt WJ; Ngu H; Gogineni A; Lalehzadeh G; Lee SH; Srinivasan K; Imperio J; Wu T; Weber M; Kruse AJ; Stark KL; Chan P; Kwong M; Modrusan Z; Friedman BA; Elstrott J; Foreman O; Easton A; Sheng M; Hansen DV J Neurosci; 2020 Feb; 40(9):1956-1974. PubMed ID: 31980586 [No Abstract] [Full Text] [Related]
15. Alzheimer's disease pathology is attenuated in a CD38-deficient mouse model. Blacher E; Dadali T; Bespalko A; Haupenthal VJ; Grimm MO; Hartmann T; Lund FE; Stein R; Levy A Ann Neurol; 2015 Jul; 78(1):88-103. PubMed ID: 25893674 [TBL] [Abstract][Full Text] [Related]
16. Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice. Maier M; Peng Y; Jiang L; Seabrook TJ; Carroll MC; Lemere CA J Neurosci; 2008 Jun; 28(25):6333-41. PubMed ID: 18562603 [TBL] [Abstract][Full Text] [Related]
17. Effects of TYROBP Deficiency on Neuroinflammation of a Alzheimer's Disease Mouse Model Carrying a Li R; Lv ZY; Li YX; Li W; Hao YL Chin Med Sci J; 2022 Dec; 37(4):320-330. PubMed ID: 36171177 [TBL] [Abstract][Full Text] [Related]
19. The effect of Karahan H; Smith DC; Kim B; McCord B; Mantor J; John SK; Al-Amin MM; Dabin LC; Kim J Front Immunol; 2023; 14():1102530. PubMed ID: 36895556 [TBL] [Abstract][Full Text] [Related]
20. Mechanism of TREM2/DAP12 complex affecting β-amyloid plaque deposition in Alzheimer's disease modeled mice through mediating inflammatory response. Cui X; Qiao J; Liu S; Wu M; Gu W Brain Res Bull; 2021 Jan; 166():21-28. PubMed ID: 33053435 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]