BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

317 related articles for article (PubMed ID: 30287686)

  • 1. Oligomerization of the HECT ubiquitin ligase NEDD4-2/NEDD4L is essential for polyubiquitin chain assembly.
    Todaro DR; Augustus-Wallace AC; Klein JM; Haas AL
    J Biol Chem; 2018 Nov; 293(47):18192-18206. PubMed ID: 30287686
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The mechanism of neural precursor cell expressed developmentally down-regulated 4-2 (Nedd4-2)/NEDD4L-catalyzed polyubiquitin chain assembly.
    Todaro DR; Augustus-Wallace AC; Klein JM; Haas AL
    J Biol Chem; 2017 Nov; 292(47):19521-19536. PubMed ID: 28972136
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The active form of E6-associated protein (E6AP)/UBE3A ubiquitin ligase is an oligomer.
    Ronchi VP; Klein JM; Edwards DJ; Haas AL
    J Biol Chem; 2014 Jan; 289(2):1033-48. PubMed ID: 24273172
    [TBL] [Abstract][Full Text] [Related]  

  • 4.
    Ronchi VP; Kim ED; Summa CM; Klein JM; Haas AL
    J Biol Chem; 2017 Nov; 292(44):18006-18023. PubMed ID: 28924046
    [TBL] [Abstract][Full Text] [Related]  

  • 5. E6AP/UBE3A ubiquitin ligase harbors two E2~ubiquitin binding sites.
    Ronchi VP; Klein JM; Haas AL
    J Biol Chem; 2013 Apr; 288(15):10349-60. PubMed ID: 23439649
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Convergent evolution in the assembly of polyubiquitin degradation signals by the Shigella flexneri IpaH9.8 ligase.
    Edwards DJ; Streich FC; Ronchi VP; Todaro DR; Haas AL
    J Biol Chem; 2014 Dec; 289(49):34114-28. PubMed ID: 25342744
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Analysis of ubiquitin recognition by the HECT ligase E6AP provides insight into its linkage specificity.
    Ries LK; Sander B; Deol KK; Letzelter MA; Strieter ER; Lorenz S
    J Biol Chem; 2019 Apr; 294(15):6113-6129. PubMed ID: 30737286
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activities
    Singh S; Ng J; Nayak D; Sivaraman J
    J Biol Chem; 2019 Dec; 294(52):19934-19949. PubMed ID: 31732561
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism of ubiquitin chain synthesis employed by a HECT domain ubiquitin ligase.
    French ME; Klosowiak JL; Aslanian A; Reed SI; Yates JR; Hunter T
    J Biol Chem; 2017 Jun; 292(25):10398-10413. PubMed ID: 28461335
    [No Abstract]   [Full Text] [Related]  

  • 10. Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes.
    Vina-Vilaseca A; Sorkin A
    J Biol Chem; 2010 Mar; 285(10):7645-56. PubMed ID: 20051513
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ubiquitin chain specificities of E6AP E3 ligase and its HECT domain.
    Kobayashi F; Nishiuchi T; Takaki K; Konno H
    Biochem Biophys Res Commun; 2018 Feb; 496(2):686-692. PubMed ID: 29288669
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural Dynamics of E6AP E3 Ligase HECT Domain and Involvement of a Flexible Hinge Loop in the Ubiquitin Chain Synthesis Mechanism.
    Takeda K; Flechsig H; Muro I; Amyot R; Kobayashi F; Kodera N; Ando T; Konno H
    Nano Lett; 2023 Dec; 23(24):11940-11948. PubMed ID: 38055898
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative analysis of the catalytic regulation of NEDD4-1 and WWP2 ubiquitin ligases.
    Jiang H; Thomas SN; Chen Z; Chiang CY; Cole PA
    J Biol Chem; 2019 Nov; 294(46):17421-17436. PubMed ID: 31578285
    [TBL] [Abstract][Full Text] [Related]  

  • 14. β-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation.
    Jäckl M; Stollmaier C; Strohäker T; Hyz K; Maspero E; Polo S; Wiesner S
    J Mol Biol; 2018 Sep; 430(18 Pt B):3218-3233. PubMed ID: 29964046
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch.
    Zhu K; Shan Z; Chen X; Cai Y; Cui L; Yao W; Wang Z; Shi P; Tian C; Lou J; Xie Y; Wen W
    EMBO Rep; 2017 Sep; 18(9):1618-1630. PubMed ID: 28747490
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Emerging roles of the HECT E3 ubiquitin ligases in gastric cancer.
    Sun A; Tian X; Chen Y; Yang W; Lin Q
    Pathol Oncol Res; 2023; 29():1610931. PubMed ID: 36825281
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of NEDD4 related HECT-type E3 ubiquitin ligases in defective autophagy in cancer cells: molecular mechanisms and therapeutic perspectives.
    Zhang R; Shi S
    Mol Med; 2023 Mar; 29(1):34. PubMed ID: 36918822
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Polyubiquitination by HECT E3s and the determinants of chain type specificity.
    Kim HC; Huibregtse JM
    Mol Cell Biol; 2009 Jun; 29(12):3307-18. PubMed ID: 19364824
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Physiological Functions of the Ubiquitin Ligases Nedd4-1 and Nedd4-2.
    Rotin D; Prag G
    Physiology (Bethesda); 2024 Jan; 39(1):18-29. PubMed ID: 37962894
    [TBL] [Abstract][Full Text] [Related]  

  • 20. UbFluor: A Fluorescent Thioester to Monitor HECT E3 Ligase Catalysis.
    Krist DT; Foote PK; Statsyuk AV
    Curr Protoc Chem Biol; 2017 Mar; 9(1):11-37. PubMed ID: 28253433
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.