These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 30289386)

  • 1. Simulation of spontaneous G protein activation reveals a new intermediate driving GDP unbinding.
    Sun X; Singh S; Blumer KJ; Bowman GR
    Elife; 2018 Oct; 7():. PubMed ID: 30289386
    [TBL] [Abstract][Full Text] [Related]  

  • 2. GDP Release from the Open Conformation of Gα Requires Allosteric Signaling from the Agonist-Bound Human β
    Kumar V; Hoag H; Sader S; Scorese N; Liu H; Wu C
    J Chem Inf Model; 2020 Aug; 60(8):4064-4075. PubMed ID: 32786510
    [TBL] [Abstract][Full Text] [Related]  

  • 3. GDP release preferentially occurs on the phosphate side in heterotrimeric G-proteins.
    Louet M; Martinez J; Floquet N
    PLoS Comput Biol; 2012; 8(7):e1002595. PubMed ID: 22829757
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Universal allosteric mechanism for Gα activation by GPCRs.
    Flock T; Ravarani CNJ; Sun D; Venkatakrishnan AJ; Kayikci M; Tate CG; Veprintsev DB; Babu MM
    Nature; 2015 Aug; 524(7564):173-179. PubMed ID: 26147082
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Computational Simulation of the Activation Cycle of Gα Subunit in the G Protein Cycle Using an Elastic Network Model.
    Kim MH; Kim YJ; Kim HR; Jeon TJ; Choi JB; Chung KY; Kim MK
    PLoS One; 2016; 11(8):e0159528. PubMed ID: 27483005
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A transient interaction between the phosphate binding loop and switch I contributes to the allosteric network between receptor and nucleotide in Gαi1.
    Thaker TM; Sarwar M; Preininger AM; Hamm HE; Iverson TM
    J Biol Chem; 2014 Apr; 289(16):11331-11341. PubMed ID: 24596087
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conformational flexibility and structural dynamics in GPCR-mediated G protein activation: a perspective.
    Preininger AM; Meiler J; Hamm HE
    J Mol Biol; 2013 Jul; 425(13):2288-98. PubMed ID: 23602809
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A concerted mechanism for opening the GDP binding pocket and release of the nucleotide in hetero-trimeric G-proteins.
    Louet M; Perahia D; Martinez J; Floquet N
    J Mol Biol; 2011 Aug; 411(1):298-312. PubMed ID: 21663745
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit.
    Van Eps N; Preininger AM; Alexander N; Kaya AI; Meier S; Meiler J; Hamm HE; Hubbell WL
    Proc Natl Acad Sci U S A; 2011 Jun; 108(23):9420-4. PubMed ID: 21606326
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nucleotide binding switches the information flow in ras GTPases.
    Raimondi F; Portella G; Orozco M; Fanelli F
    PLoS Comput Biol; 2011 Mar; 7(3):e1001098. PubMed ID: 21390270
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nullspace Sampling with Holonomic Constraints Reveals Molecular Mechanisms of Protein Gαs.
    Pachov DV; van den Bedem H
    PLoS Comput Biol; 2015 Jul; 11(7):e1004361. PubMed ID: 26218073
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conformational switch that induces GDP release from Gi.
    Ham D; Ahn D; Ashim J; Cho Y; Kim HR; Yu W; Chung KY
    J Struct Biol; 2021 Mar; 213(1):107694. PubMed ID: 33418033
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural insights into G protein activation by D1 dopamine receptor.
    Teng X; Chen S; Wang Q; Chen Z; Wang X; Huang N; Zheng S
    Sci Adv; 2022 Jun; 8(23):eabo4158. PubMed ID: 35687690
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Coordinate regulation of G protein signaling via dynamic interactions of receptor and GAP.
    Turcotte M; Tang W; Ross EM
    PLoS Comput Biol; 2008 Aug; 4(8):e1000148. PubMed ID: 18716678
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interactions between the amino- and carboxyl-terminal regions of G alpha subunits: analysis of mutated G alpha o/G alpha i2 chimeras.
    Denker BM; Boutin PM; Neer EJ
    Biochemistry; 1995 Apr; 34(16):5544-53. PubMed ID: 7727415
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural evidence for a sequential release mechanism for activation of heterotrimeric G proteins.
    Kapoor N; Menon ST; Chauhan R; Sachdev P; Sakmar TP
    J Mol Biol; 2009 Nov; 393(4):882-97. PubMed ID: 19703466
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A conserved phenylalanine as a relay between the α5 helix and the GDP binding region of heterotrimeric Gi protein α subunit.
    Kaya AI; Lokits AD; Gilbert JA; Iverson TM; Meiler J; Hamm HE
    J Biol Chem; 2014 Aug; 289(35):24475-87. PubMed ID: 25037222
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural and biochemical properties show ARL3-GDP as a distinct GTP binding protein.
    Hillig RC; Hanzal-Bayer M; Linari M; Becker J; Wittinghofer A; Renault L
    Structure; 2000 Dec; 8(12):1239-45. PubMed ID: 11188688
    [TBL] [Abstract][Full Text] [Related]  

  • 19. GTP is an allosteric modulator of the interaction between the guanylate-binding protein 1 and the prosurvival kinase PIM1.
    Persico M; Petrella L; Orteca N; Di Dato A; Mariani M; Andreoli M; De Donato M; Scambia G; Novellino E; Ferlini C; Fattorusso C
    Eur J Med Chem; 2015 Feb; 91():132-44. PubMed ID: 25081641
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Conformational Dynamics of Heterotrimeric G Proteins During GPCR-Mediated Activation.
    Ahn D; Chung KY
    Subcell Biochem; 2022; 99():271-284. PubMed ID: 36151379
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.