These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 30290153)

  • 1. Activating Mutations in PAK1, Encoding p21-Activated Kinase 1, Cause a Neurodevelopmental Disorder.
    Harms FL; Kloth K; Bley A; Denecke J; Santer R; Lessel D; Hempel M; Kutsche K
    Am J Hum Genet; 2018 Oct; 103(4):579-591. PubMed ID: 30290153
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel PAK1 variant causative of neurodevelopmental disorder with postnatal macrocephaly.
    Ohori S; Mitsuhashi S; Ben-Haim R; Heyman E; Sengoku T; Ogata K; Matsumoto N
    J Hum Genet; 2020 May; 65(5):481-485. PubMed ID: 32005903
    [TBL] [Abstract][Full Text] [Related]  

  • 3. De novo variants in PAK1 lead to intellectual disability with macrocephaly and seizures.
    Horn S; Au M; Basel-Salmon L; Bayrak-Toydemir P; Chapin A; Cohen L; Elting MW; Graham JM; Gonzaga-Jauregui C; Konen O; Holzer M; Lemke J; Miller CE; Rey LK; Wolf NI; Weiss MM; Waisfisz Q; Mirzaa GM; Wieczorek D; Sticht H; Abou Jamra R
    Brain; 2019 Nov; 142(11):3351-3359. PubMed ID: 31504246
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Association of PI-3 kinase with PAK1 leads to actin phosphorylation and cytoskeletal reorganization.
    Papakonstanti EA; Stournaras C
    Mol Biol Cell; 2002 Aug; 13(8):2946-62. PubMed ID: 12181358
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RIT1 controls actin dynamics via complex formation with RAC1/CDC42 and PAK1.
    Meyer Zum Büschenfelde U; Brandenstein LI; von Elsner L; Flato K; Holling T; Zenker M; Rosenberger G; Kutsche K
    PLoS Genet; 2018 May; 14(5):e1007370. PubMed ID: 29734338
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1.
    Parrini MC; Lei M; Harrison SC; Mayer BJ
    Mol Cell; 2002 Jan; 9(1):73-83. PubMed ID: 11804587
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells.
    Sells MA; Knaus UG; Bagrodia S; Ambrose DM; Bokoch GM; Chernoff J
    Curr Biol; 1997 Mar; 7(3):202-10. PubMed ID: 9395435
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Temporal and spatial distribution of activated Pak1 in fibroblasts.
    Sells MA; Pfaff A; Chernoff J
    J Cell Biol; 2000 Dec; 151(7):1449-58. PubMed ID: 11134074
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Mutations in the Effector Domain of RhoV GTPase Impair Its Binding to Pak1 Protein Kinase].
    Korobko IV; Shepelev MV
    Mol Biol (Mosk); 2018; 52(4):692-698. PubMed ID: 30113035
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Analysis of small GTPase signaling pathways using p21-activated kinase mutants that selectively couple to Cdc42.
    Reeder MK; Serebriiskii IG; Golemis EA; Chernoff J
    J Biol Chem; 2001 Nov; 276(44):40606-13. PubMed ID: 11514549
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp.
    Weisz Hubsman M; Volinsky N; Manser E; Yablonski D; Aronheim A
    Biochem J; 2007 Jun; 404(3):487-97. PubMed ID: 17355222
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p70 S6 kinase in the control of actin cytoskeleton dynamics and directed migration of ovarian cancer cells.
    Ip CK; Cheung AN; Ngan HY; Wong AS
    Oncogene; 2011 May; 30(21):2420-32. PubMed ID: 21258406
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics.
    Edwards DC; Sanders LC; Bokoch GM; Gill GN
    Nat Cell Biol; 1999 Sep; 1(5):253-9. PubMed ID: 10559936
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways.
    Lim L; Manser E; Leung T; Hall C
    Eur J Biochem; 1996 Dec; 242(2):171-85. PubMed ID: 8973630
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A PAK1 Mutational Hotspot Within the Regulatory CRIPaK Domain is Associated With Severe Neurodevelopmental Disorders in Children.
    Scorrano G; D'Onofrio G; Accogli A; Severino M; Buchert R; Kotzaeridou U; Iapadre G; Farello G; Iacomino M; Dono F; Di Francesco L; Fiorile MF; La Bella S; Corsello A; Calì E; Di Rosa G; Gitto E; Verrotti A; Fortuna S; Soler MA; Chiarelli F; Oehl-Jaschkowitz B; Haack TB; Zara F; Striano P; Salpietro V
    Pediatr Neurol; 2023 Dec; 149():84-92. PubMed ID: 37820543
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synergistic activation of p21-activated kinase 1 by phosphatidylinositol 4,5-bisphosphate and Rho GTPases.
    Malecka KA; Szentpetery Z; Peterson JR
    J Biol Chem; 2013 Mar; 288(13):8887-97. PubMed ID: 23393142
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase.
    Barrows D; Schoenfeld SM; Hodakoski C; Silkov A; Honig B; Couvillon A; Shymanets A; Nürnberg B; Asara JM; Parsons R
    J Biol Chem; 2015 Nov; 290(48):28915-31. PubMed ID: 26438819
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Localization of p21-activated kinase 1 (PAK1) to pseudopodia, membrane ruffles, and phagocytic cups in activated human neutrophils.
    Dharmawardhane S; Brownson D; Lennartz M; Bokoch GM
    J Leukoc Biol; 1999 Sep; 66(3):521-7. PubMed ID: 10496324
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Localization of p21-activated kinase 1 (PAK1) to pinocytic vesicles and cortical actin structures in stimulated cells.
    Dharmawardhane S; Sanders LC; Martin SS; Daniels RH; Bokoch GM
    J Cell Biol; 1997 Sep; 138(6):1265-78. PubMed ID: 9298982
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oncogenic mutations on Rac1 affect global intrinsic dynamics underlying GTP and PAK1 binding.
    Acuner SE; Sumbul F; Torun H; Haliloglu T
    Biophys J; 2021 Mar; 120(5):866-876. PubMed ID: 33515600
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.