750 related articles for article (PubMed ID: 30292559)
1. Normalizing glucocorticoid levels attenuates metabolic and neuropathological symptoms in the R6/2 mouse model of huntington's disease.
Dufour BD; McBride JL
Neurobiol Dis; 2019 Jan; 121():214-229. PubMed ID: 30292559
[TBL] [Abstract][Full Text] [Related]
2. Corticosterone dysregulation exacerbates disease progression in the R6/2 transgenic mouse model of Huntington's disease.
Dufour BD; McBride JL
Exp Neurol; 2016 Sep; 283(Pt A):308-17. PubMed ID: 27381424
[TBL] [Abstract][Full Text] [Related]
3. Glucocorticoid receptor antagonist CORT113176 attenuates motor and neuropathological symptoms of Huntington's disease in R6/2 mice.
Gentenaar M; Meulmeester FL; van der Burg XR; Hoekstra AT; Hunt H; Kroon J; van Roon-Mom WMC; Meijer OC
Exp Neurol; 2024 Apr; 374():114675. PubMed ID: 38216109
[TBL] [Abstract][Full Text] [Related]
4. Microglial physiological properties and interactions with synapses are altered at presymptomatic stages in a mouse model of Huntington's disease pathology.
Savage JC; St-Pierre MK; Carrier M; El Hajj H; Novak SW; Sanchez MG; Cicchetti F; Tremblay MÈ
J Neuroinflammation; 2020 Apr; 17(1):98. PubMed ID: 32241286
[TBL] [Abstract][Full Text] [Related]
5. Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease.
Björkqvist M; Petersén A; Bacos K; Isaacs J; Norlén P; Gil J; Popovic N; Sundler F; Bates GP; Tabrizi SJ; Brundin P; Mulder H
Hum Mol Genet; 2006 May; 15(10):1713-21. PubMed ID: 16613897
[TBL] [Abstract][Full Text] [Related]
6. Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis.
Onur TS; Laitman A; Zhao H; Keyho R; Kim H; Wang J; Mair M; Wang H; Li L; Perez A; de Haro M; Wan YW; Allen G; Lu B; Al-Ramahi I; Liu Z; Botas J
Elife; 2021 Apr; 10():. PubMed ID: 33871358
[TBL] [Abstract][Full Text] [Related]
7. AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease.
Ju TC; Chen HM; Chen YC; Chang CP; Chang C; Chern Y
Biochim Biophys Acta; 2014 Sep; 1842(9):1668-80. PubMed ID: 24946181
[TBL] [Abstract][Full Text] [Related]
8. Activation of NPY-Y2 receptors ameliorates disease pathology in the R6/2 mouse and PC12 cell models of Huntington's disease.
Fatoba O; Kloster E; Reick C; Saft C; Gold R; Epplen JT; Arning L; Ellrichmann G
Exp Neurol; 2018 Apr; 302():112-128. PubMed ID: 29309751
[TBL] [Abstract][Full Text] [Related]
9. Hypothalamic expression of huntingtin causes distinct metabolic changes in Huntington's disease mice.
Dickson E; Soylu-Kucharz R; Petersén Å; Björkqvist M
Mol Metab; 2022 Mar; 57():101439. PubMed ID: 35007790
[TBL] [Abstract][Full Text] [Related]
10. Exercise attenuates neuropathology and has greater benefit on cognitive than motor deficits in the R6/1 Huntington's disease mouse model.
Harrison DJ; Busse M; Openshaw R; Rosser AE; Dunnett SB; Brooks SP
Exp Neurol; 2013 Oct; 248():457-69. PubMed ID: 23911978
[TBL] [Abstract][Full Text] [Related]
11. Neurogenesis in the R6/2 mouse model of Huntington's disease is impaired at the level of NeuroD1.
Fedele V; Roybon L; Nordström U; Li JY; Brundin P
Neuroscience; 2011 Jan; 173():76-81. PubMed ID: 20807561
[TBL] [Abstract][Full Text] [Related]
12. Intravenous immunoglobulin ameliorates motor and cognitive deficits and neuropathology in R6/2 mouse model of Huntington's disease by decreasing mutant huntingtin protein level and normalizing NF-κB signaling pathway.
Liu SY; Yu XL; Zhu J; Liu XM; Zhang Y; Dong QX; Ma S; Liu RT
Brain Res; 2018 Oct; 1697():21-33. PubMed ID: 29902468
[TBL] [Abstract][Full Text] [Related]
13. Intrajugular vein delivery of AAV9-RNAi prevents neuropathological changes and weight loss in Huntington's disease mice.
Dufour BD; Smith CA; Clark RL; Walker TR; McBride JL
Mol Ther; 2014 Apr; 22(4):797-810. PubMed ID: 24390280
[TBL] [Abstract][Full Text] [Related]
14. Treatment with JQ1, a BET bromodomain inhibitor, is selectively detrimental to R6/2 Huntington's disease mice.
Kedaigle AJ; Reidling JC; Lim RG; Adam M; Wu J; Wassie B; Stocksdale JT; Casale MS; Fraenkel E; Thompson LM
Hum Mol Genet; 2020 Jan; 29(2):202-215. PubMed ID: 31696228
[TBL] [Abstract][Full Text] [Related]
15. Effects of chronic stress on the onset and progression of Huntington's disease in transgenic mice.
Mo C; Renoir T; Hannan AJ
Neurobiol Dis; 2014 Nov; 71():81-94. PubMed ID: 25088714
[TBL] [Abstract][Full Text] [Related]
16. Impaired basal and running-induced hippocampal neurogenesis coincides with reduced Akt signaling in adult R6/1 HD mice.
Ransome MI; Hannan AJ
Mol Cell Neurosci; 2013 May; 54():93-107. PubMed ID: 23384443
[TBL] [Abstract][Full Text] [Related]
17. Correlations of behavioral deficits with brain pathology assessed through longitudinal MRI and histopathology in the R6/1 mouse model of Huntington's disease.
Rattray I; Smith EJ; Crum WR; Walker TA; Gale R; Bates GP; Modo M
PLoS One; 2013; 8(12):e84726. PubMed ID: 24367693
[TBL] [Abstract][Full Text] [Related]
18. Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes.
Chou SY; Weng JY; Lai HL; Liao F; Sun SH; Tu PH; Dickson DW; Chern Y
J Neurosci; 2008 Mar; 28(13):3277-90. PubMed ID: 18367595
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of GSK-3 ameliorates the pathogenesis of Huntington's disease.
Rippin I; Bonder K; Joseph S; Sarsor A; Vaks L; Eldar-Finkelman H
Neurobiol Dis; 2021 Jul; 154():105336. PubMed ID: 33753290
[TBL] [Abstract][Full Text] [Related]
20. A selective inhibitor of the NLRP3 inflammasome as a potential therapeutic approach for neuroprotection in a transgenic mouse model of Huntington's disease.
Chen KP; Hua KF; Tsai FT; Lin TY; Cheng CY; Yang DI; Hsu HT; Ju TC
J Neuroinflammation; 2022 Feb; 19(1):56. PubMed ID: 35219323
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]