These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
393 related articles for article (PubMed ID: 30295169)
1. A Brief Introduction to Antibody-Drug Conjugates for Toxicologic Pathologists. Mecklenburg L Toxicol Pathol; 2018 Oct; 46(7):746-752. PubMed ID: 30295169 [TBL] [Abstract][Full Text] [Related]
2. Considerations for the nonclinical safety evaluation of antibody drug conjugates for oncology. Roberts SA; Andrews PA; Blanset D; Flagella KM; Gorovits B; Lynch CM; Martin PL; Kramer-Stickland K; Thibault S; Warner G Regul Toxicol Pharmacol; 2013 Dec; 67(3):382-91. PubMed ID: 24012707 [TBL] [Abstract][Full Text] [Related]
3. Effects of Drug-Antibody Ratio on Pharmacokinetics, Biodistribution, Efficacy, and Tolerability of Antibody-Maytansinoid Conjugates. Sun X; Ponte JF; Yoder NC; Laleau R; Coccia J; Lanieri L; Qiu Q; Wu R; Hong E; Bogalhas M; Wang L; Dong L; Setiady Y; Maloney EK; Ab O; Zhang X; Pinkas J; Keating TA; Chari R; Erickson HK; Lambert JM Bioconjug Chem; 2017 May; 28(5):1371-1381. PubMed ID: 28388844 [TBL] [Abstract][Full Text] [Related]
4. Peripheral neuropathy with microtubule inhibitor containing antibody drug conjugates: Challenges and perspectives in translatability from nonclinical toxicology studies to the clinic. Stagg NJ; Shen BQ; Brunstein F; Li C; Kamath AV; Zhong F; Schutten M; Fine BM Regul Toxicol Pharmacol; 2016 Dec; 82():1-13. PubMed ID: 27773754 [TBL] [Abstract][Full Text] [Related]
5. Catabolism of antibody drug conjugates and characterization methods. Shadid M; Bowlin S; Bolleddula J Bioorg Med Chem; 2017 Jun; 25(12):2933-2945. PubMed ID: 28438386 [TBL] [Abstract][Full Text] [Related]
6. Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models. Li F; Emmerton KK; Jonas M; Zhang X; Miyamoto JB; Setter JR; Nicholas ND; Okeley NM; Lyon RP; Benjamin DR; Law CL Cancer Res; 2016 May; 76(9):2710-9. PubMed ID: 26921341 [TBL] [Abstract][Full Text] [Related]
7. Antibody-Drug Conjugates as Cancer Therapeutics: Past, Present, and Future. Vezina HE; Cotreau M; Han TH; Gupta M J Clin Pharmacol; 2017 Oct; 57 Suppl 10():S11-S25. PubMed ID: 28921650 [TBL] [Abstract][Full Text] [Related]
8. Duocarmycin-based antibody-drug conjugates as an emerging biotherapeutic entity for targeted cancer therapy: Pharmaceutical strategy and clinical progress. Yao HP; Zhao H; Hudson R; Tong XM; Wang MH Drug Discov Today; 2021 Aug; 26(8):1857-1874. PubMed ID: 34224904 [TBL] [Abstract][Full Text] [Related]
9. Internalization, Trafficking, Intracellular Processing and Actions of Antibody-Drug Conjugates. Xu S Pharm Res; 2015 Nov; 32(11):3577-83. PubMed ID: 26108878 [TBL] [Abstract][Full Text] [Related]
10. Characterization of Site-Specifically Conjugated Monomethyl Auristatin E- and Duocarmycin-Based Anti-PSMA Antibody-Drug Conjugates for Treatment of PSMA-Expressing Tumors. Lütje S; Gerrits D; Molkenboer-Kuenen JD; Herrmann K; Fracasso G; Colombatti M; Boerman OC; Heskamp S J Nucl Med; 2018 Mar; 59(3):494-501. PubMed ID: 29146698 [TBL] [Abstract][Full Text] [Related]
11. An FDA oncology analysis of antibody-drug conjugates. Saber H; Leighton JK Regul Toxicol Pharmacol; 2015 Apr; 71(3):444-52. PubMed ID: 25661711 [TBL] [Abstract][Full Text] [Related]
12. Carfilzomib Is Not an Appropriate Payload of Antibody-Drug Conjugates Due to Rapid Inactivation by Lysosomal Enzymes. Ma Y; Dela Cruz-Chuh J; Khojasteh SC; Dragovich PS; Pillow TH; Zhang D Drug Metab Dispos; 2019 Aug; 47(8):884-889. PubMed ID: 31072822 [TBL] [Abstract][Full Text] [Related]
13. Contribution of linker stability to the activities of anticancer immunoconjugates. Alley SC; Benjamin DR; Jeffrey SC; Okeley NM; Meyer DL; Sanderson RJ; Senter PD Bioconjug Chem; 2008 Mar; 19(3):759-65. PubMed ID: 18314937 [TBL] [Abstract][Full Text] [Related]
15. A Case Study Comparing Heterogeneous Lysine- and Site-Specific Cysteine-Conjugated Maytansinoid Antibody-Drug Conjugates (ADCs) Illustrates the Benefits of Lysine Conjugation. Yoder NC; Bai C; Tavares D; Widdison WC; Whiteman KR; Wilhelm A; Wilhelm SD; McShea MA; Maloney EK; Ab O; Wang L; Jin S; Erickson HK; Keating TA; Lambert JM Mol Pharm; 2019 Sep; 16(9):3926-3937. PubMed ID: 31287952 [TBL] [Abstract][Full Text] [Related]
16. Tandem-Cleavage Linkers Improve the In Vivo Stability and Tolerability of Antibody-Drug Conjugates. Chuprakov S; Ogunkoya AO; Barfield RM; Bauzon M; Hickle C; Kim YC; Yeo D; Zhang F; Rabuka D; Drake PM Bioconjug Chem; 2021 Apr; 32(4):746-754. PubMed ID: 33689309 [TBL] [Abstract][Full Text] [Related]
17. Pharmacokinetic Considerations for Antibody-Drug Conjugates against Cancer. Malik P; Phipps C; Edginton A; Blay J Pharm Res; 2017 Dec; 34(12):2579-2595. PubMed ID: 28924691 [TBL] [Abstract][Full Text] [Related]
18. Potential drugs used in the antibody-drug conjugate (ADC) architecture for cancer therapy. Yaghoubi S; Karimi MH; Lotfinia M; Gharibi T; Mahi-Birjand M; Kavi E; Hosseini F; Sineh Sepehr K; Khatami M; Bagheri N; Abdollahpour-Alitappeh M J Cell Physiol; 2020 Jan; 235(1):31-64. PubMed ID: 31215038 [TBL] [Abstract][Full Text] [Related]
19. Antibody-drug conjugates in tumor therapy. Sammet B; Steinkühler C; Sewald N Pharm Pat Anal; 2012 Mar; 1(1):65-73. PubMed ID: 24236714 [TBL] [Abstract][Full Text] [Related]
20. Chemical Site-Specific Conjugation Platform to Improve the Pharmacokinetics and Therapeutic Index of Antibody-Drug Conjugates. Matsuda Y; Seki T; Yamada K; Ooba Y; Takahashi K; Fujii T; Kawaguchi S; Narita T; Nakayama A; Kitahara Y; Mendelsohn BA; Okuzumi T Mol Pharm; 2021 Nov; 18(11):4058-4066. PubMed ID: 34579528 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]