730 related articles for article (PubMed ID: 30296051)
1. 4,6-Diphenylpyrimidine Derivatives as Dual Inhibitors of Monoamine Oxidase and Acetylcholinesterase for the Treatment of Alzheimer's Disease.
Kumar B; Dwivedi AR; Sarkar B; Gupta SK; Krishnamurthy S; Mantha AK; Parkash J; Kumar V
ACS Chem Neurosci; 2019 Jan; 10(1):252-265. PubMed ID: 30296051
[TBL] [Abstract][Full Text] [Related]
2. Dipropargyl substituted diphenylpyrimidines as dual inhibitors of monoamine oxidase and acetylcholinesterase.
Kumar B; Kumar V; Prashar V; Saini S; Dwivedi AR; Bajaj B; Mehta D; Parkash J; Kumar V
Eur J Med Chem; 2019 Sep; 177():221-234. PubMed ID: 31151057
[TBL] [Abstract][Full Text] [Related]
3. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents.
Košak U; Strašek N; Knez D; Jukič M; Žakelj S; Zahirović A; Pišlar A; Brazzolotto X; Nachon F; Kos J; Gobec S
Eur J Med Chem; 2020 Jul; 197():112282. PubMed ID: 32380361
[TBL] [Abstract][Full Text] [Related]
4. Exploration of a Library of 3,4-(Methylenedioxy)aniline-Derived Semicarbazones as Dual Inhibitors of Monoamine Oxidase and Acetylcholinesterase: Design, Synthesis, and Evaluation.
Tripathi RK; Rai GK; Ayyannan SR
ChemMedChem; 2016 Jun; 11(11):1145-60. PubMed ID: 27135466
[TBL] [Abstract][Full Text] [Related]
5. Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine.
Samadi A; de los Ríos C; Bolea I; Chioua M; Iriepa I; Moraleda I; Bartolini M; Andrisano V; Gálvez E; Valderas C; Unzeta M; Marco-Contelles J
Eur J Med Chem; 2012 Jun; 52():251-62. PubMed ID: 22503231
[TBL] [Abstract][Full Text] [Related]
6. Site-activated multi target iron chelators with acetylcholinesterase (AChE) and monoamine oxidase (MAO) inhibitory activities for Alzheimer's disease therapy.
Youdim MBH
J Neural Transm (Vienna); 2022 Jun; 129(5-6):715-721. PubMed ID: 35190910
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase/monoamine oxidase inhibitors for the potential application against Alzheimer's disease.
Li F; Wang ZM; Wu JJ; Wang J; Xie SS; Lan JS; Xu W; Kong LY; Wang XB
J Enzyme Inhib Med Chem; 2016; 31(sup3):41-53. PubMed ID: 27384289
[TBL] [Abstract][Full Text] [Related]
8. Design, Synthesis, and Pharmacological Evaluation of
Kumar B; Dwivedi AR; Arora T; Raj K; Prashar V; Kumar V; Singh S; Prakash J; Kumar V
ACS Chem Neurosci; 2022 Jul; 13(14):2122-2139. PubMed ID: 35797244
[TBL] [Abstract][Full Text] [Related]
9. Pyridoxine-resveratrol hybrids Mannich base derivatives as novel dual inhibitors of AChE and MAO-B with antioxidant and metal-chelating properties for the treatment of Alzheimer's disease.
Yang X; Qiang X; Li Y; Luo L; Xu R; Zheng Y; Cao Z; Tan Z; Deng Y
Bioorg Chem; 2017 Apr; 71():305-314. PubMed ID: 28267984
[TBL] [Abstract][Full Text] [Related]
10. Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids.
Bautista-Aguilera OM; Esteban G; Chioua M; Nikolic K; Agbaba D; Moraleda I; Iriepa I; Soriano E; Samadi A; Unzeta M; Marco-Contelles J
Drug Des Devel Ther; 2014; 8():1893-910. PubMed ID: 25378907
[TBL] [Abstract][Full Text] [Related]
11. Multitarget drug design strategy against Alzheimer's disease: Homoisoflavonoid Mannich base derivatives serve as acetylcholinesterase and monoamine oxidase B dual inhibitors with multifunctional properties.
Li Y; Qiang X; Luo L; Yang X; Xiao G; Zheng Y; Cao Z; Sang Z; Su F; Deng Y
Bioorg Med Chem; 2017 Jan; 25(2):714-726. PubMed ID: 27923535
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and pharmacological evaluation of 2-amino-5-nitrothiazole derived semicarbazones as dual inhibitors of monoamine oxidase and cholinesterase: effect of the size of aryl binding site.
Tripathi RKP; M Sasi V; Gupta SK; Krishnamurthy S; Ayyannan SR
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):37-57. PubMed ID: 29098902
[TBL] [Abstract][Full Text] [Related]
13. Coumarin-dithiocarbamate hybrids as novel multitarget AChE and MAO-B inhibitors against Alzheimer's disease: Design, synthesis and biological evaluation.
He Q; Liu J; Lan JS; Ding J; Sun Y; Fang Y; Jiang N; Yang Z; Sun L; Jin Y; Xie SS
Bioorg Chem; 2018 Dec; 81():512-528. PubMed ID: 30245233
[TBL] [Abstract][Full Text] [Related]
14. Rational Design of Novel Selective Dual-Target Inhibitors of Acetylcholinesterase and Monoamine Oxidase B as Potential Anti-Alzheimer's Disease Agents.
Xu Y; Zhang J; Wang H; Mao F; Bao K; Liu W; Zhu J; Li X; Zhang H; Li J
ACS Chem Neurosci; 2019 Jan; 10(1):482-496. PubMed ID: 30110536
[TBL] [Abstract][Full Text] [Related]
15. Dual functional cholinesterase and MAO inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of homoisoflavonoid derivatives.
Wang Y; Sun Y; Guo Y; Wang Z; Huang L; Li X
J Enzyme Inhib Med Chem; 2016; 31(3):389-97. PubMed ID: 25798687
[TBL] [Abstract][Full Text] [Related]
16. Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease.
Wang L; Esteban G; Ojima M; Bautista-Aguilera OM; Inokuchi T; Moraleda I; Iriepa I; Samadi A; Youdim MB; Romero A; Soriano E; Herrero R; Fernández Fernández AP; Ricardo-Martínez-Murillo ; Marco-Contelles J; Unzeta M
Eur J Med Chem; 2014 Jun; 80():543-61. PubMed ID: 24813882
[TBL] [Abstract][Full Text] [Related]
17. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
Bolea I; Juárez-Jiménez J; de Los Ríos C; Chioua M; Pouplana R; Luque FJ; Unzeta M; Marco-Contelles J; Samadi A
J Med Chem; 2011 Dec; 54(24):8251-70. PubMed ID: 22023459
[TBL] [Abstract][Full Text] [Related]
18. Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Xu YX; Wang H; Li XK; Dong SN; Liu WW; Gong Q; Wang TD; Tang Y; Zhu J; Li J; Zhang HY; Mao F
Eur J Med Chem; 2018 Jan; 143():33-47. PubMed ID: 29172081
[TBL] [Abstract][Full Text] [Related]
19. Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents.
Pisani L; Farina R; Catto M; Iacobazzi RM; Nicolotti O; Cellamare S; Mangiatordi GF; Denora N; Soto-Otero R; Siragusa L; Altomare CD; Carotti A
J Med Chem; 2016 Jul; 59(14):6791-806. PubMed ID: 27347731
[TBL] [Abstract][Full Text] [Related]
20. Morpholine-based chalcones as dual-acting monoamine oxidase-B and acetylcholinesterase inhibitors: synthesis and biochemical investigations.
Sasidharan R; Eom BH; Heo JH; Park JE; Abdelgawad MA; Musa A; Gambacorta N; Nicolotti O; Manju SL; Mathew B; Kim H
J Enzyme Inhib Med Chem; 2021 Dec; 36(1):188-197. PubMed ID: 33430657
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]