305 related articles for article (PubMed ID: 30297966)
1. Functional architecture of low-frequency variants highlights strength of negative selection across coding and non-coding annotations.
Gazal S; Loh PR; Finucane HK; Ganna A; Schoech A; Sunyaev S; Price AL
Nat Genet; 2018 Nov; 50(11):1600-1607. PubMed ID: 30297966
[TBL] [Abstract][Full Text] [Related]
2. Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection.
Schoech AP; Jordan DM; Loh PR; Gazal S; O'Connor LJ; Balick DJ; Palamara PF; Finucane HK; Sunyaev SR; Price AL
Nat Commun; 2019 Feb; 10(1):790. PubMed ID: 30770844
[TBL] [Abstract][Full Text] [Related]
3. Integrating variant functional annotation scores have varied abilities to improve power of genome-wide association studies.
Gao J; Espin-Garcia O; Paterson AD; Sun L
Sci Rep; 2022 Jun; 12(1):10720. PubMed ID: 35750789
[TBL] [Abstract][Full Text] [Related]
4. Incorporating Non-Coding Annotations into Rare Variant Analysis.
Richardson TG; Campbell C; Timpson NJ; Gaunt TR
PLoS One; 2016; 11(4):e0154181. PubMed ID: 27128317
[TBL] [Abstract][Full Text] [Related]
5. Negligible impact of rare autoimmune-locus coding-region variants on missing heritability.
Hunt KA; Mistry V; Bockett NA; Ahmad T; Ban M; Barker JN; Barrett JC; Blackburn H; Brand O; Burren O; Capon F; Compston A; Gough SC; Jostins L; Kong Y; Lee JC; Lek M; MacArthur DG; Mansfield JC; Mathew CG; Mein CA; Mirza M; Nutland S; Onengut-Gumuscu S; Papouli E; Parkes M; Rich SS; Sawcer S; Satsangi J; Simmonds MJ; Trembath RC; Walker NM; Wozniak E; Todd JA; Simpson MA; Plagnol V; van Heel DA
Nature; 2013 Jun; 498(7453):232-5. PubMed ID: 23698362
[TBL] [Abstract][Full Text] [Related]
6. Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.
Gazal S; Finucane HK; Furlotte NA; Loh PR; Palamara PF; Liu X; Schoech A; Bulik-Sullivan B; Neale BM; Gusev A; Price AL
Nat Genet; 2017 Oct; 49(10):1421-1427. PubMed ID: 28892061
[TBL] [Abstract][Full Text] [Related]
7. Polygenic architecture of rare coding variation across 394,783 exomes.
Weiner DJ; Nadig A; Jagadeesh KA; Dey KK; Neale BM; Robinson EB; Karczewski KJ; O'Connor LJ
Nature; 2023 Feb; 614(7948):492-499. PubMed ID: 36755099
[TBL] [Abstract][Full Text] [Related]
8. The Genetic Architecture of Major Depressive Disorder in Han Chinese Women.
Peterson RE; Cai N; Bigdeli TB; Li Y; Reimers M; Nikulova A; Webb BT; Bacanu SA; Riley BP; Flint J; Kendler KS
JAMA Psychiatry; 2017 Feb; 74(2):162-168. PubMed ID: 28002544
[TBL] [Abstract][Full Text] [Related]
9. Quantifying genetic heterogeneity between continental populations for human height and body mass index.
Guo J; Bakshi A; Wang Y; Jiang L; Yengo L; Goddard ME; Visscher PM; Yang J
Sci Rep; 2021 Mar; 11(1):5240. PubMed ID: 33664403
[TBL] [Abstract][Full Text] [Related]
10. Global genetic differentiation of complex traits shaped by natural selection in humans.
Guo J; Wu Y; Zhu Z; Zheng Z; Trzaskowski M; Zeng J; Robinson MR; Visscher PM; Yang J
Nat Commun; 2018 May; 9(1):1865. PubMed ID: 29760457
[TBL] [Abstract][Full Text] [Related]
11. Rare genetic variants explain missing heritability in smoking.
Jang SK; Evans L; Fialkowski A; Arnett DK; Ashley-Koch AE; Barnes KC; Becker DM; Bis JC; Blangero J; Bleecker ER; Boorgula MP; Bowden DW; Brody JA; Cade BE; Jenkins BWC; Carson AP; Chavan S; Cupples LA; Custer B; Damrauer SM; David SP; de Andrade M; Dinardo CL; Fingerlin TE; Fornage M; Freedman BI; Garrett ME; Gharib SA; Glahn DC; Haessler J; Heckbert SR; Hokanson JE; Hou L; Hwang SJ; Hyman MC; Judy R; Justice AE; Kaplan RC; Kardia SLR; Kelly S; Kim W; Kooperberg C; Levy D; Lloyd-Jones DM; Loos RJF; Manichaikul AW; Gladwin MT; Martin LW; Nouraie M; Melander O; Meyers DA; Montgomery CG; North KE; Oelsner EC; Palmer ND; Payton M; Peljto AL; Peyser PA; Preuss M; Psaty BM; Qiao D; Rader DJ; Rafaels N; Redline S; Reed RM; Reiner AP; Rich SS; Rotter JI; Schwartz DA; Shadyab AH; Silverman EK; Smith NL; Smith JG; Smith AV; Smith JA; Tang W; Taylor KD; Telen MJ; Vasan RS; Gordeuk VR; Wang Z; Wiggins KL; Yanek LR; Yang IV; Young KA; Young KL; Zhang Y; Liu DJ; Keller MC; Vrieze S
Nat Hum Behav; 2022 Nov; 6(11):1577-1586. PubMed ID: 35927319
[TBL] [Abstract][Full Text] [Related]
12. Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individuals.
Kemper KE; Yengo L; Zheng Z; Abdellaoui A; Keller MC; Goddard ME; Wray NR; Yang J; Visscher PM
Nat Commun; 2021 Feb; 12(1):1050. PubMed ID: 33594080
[TBL] [Abstract][Full Text] [Related]
13. Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes.
Burch KS; Hou K; Ding Y; Wang Y; Gazal S; Shi H; Pasaniuc B
Am J Hum Genet; 2022 Apr; 109(4):692-709. PubMed ID: 35271803
[TBL] [Abstract][Full Text] [Related]
14. Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses.
Barton AR; Sherman MA; Mukamel RE; Loh PR
Nat Genet; 2021 Aug; 53(8):1260-1269. PubMed ID: 34226706
[TBL] [Abstract][Full Text] [Related]
15. Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability.
van de Geijn B; Finucane H; Gazal S; Hormozdiari F; Amariuta T; Liu X; Gusev A; Loh PR; Reshef Y; Kichaev G; Raychauduri S; Price AL
Hum Mol Genet; 2020 May; 29(7):1057-1067. PubMed ID: 31595288
[TBL] [Abstract][Full Text] [Related]
16. A method to estimate the contribution of rare coding variants to complex trait heritability.
Pathan N; Deng WQ; Di Scipio M; Khan M; Mao S; Morton RW; Lali R; Pigeyre M; Chong MR; Paré G
Nat Commun; 2024 Feb; 15(1):1245. PubMed ID: 38336875
[TBL] [Abstract][Full Text] [Related]
17. Evaluating the informativeness of deep learning annotations for human complex diseases.
Dey KK; van de Geijn B; Kim SS; Hormozdiari F; Kelley DR; Price AL
Nat Commun; 2020 Sep; 11(1):4703. PubMed ID: 32943643
[TBL] [Abstract][Full Text] [Related]
18. Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data.
Wainschtein P; Jain D; Zheng Z; ; ; Cupples LA; Shadyab AH; McKnight B; Shoemaker BM; Mitchell BD; Psaty BM; Kooperberg C; Liu CT; Albert CM; Roden D; Chasman DI; Darbar D; Lloyd-Jones DM; Arnett DK; Regan EA; Boerwinkle E; Rotter JI; O'Connell JR; Yanek LR; de Andrade M; Allison MA; McDonald MN; Chung MK; Fornage M; Chami N; Smith NL; Ellinor PT; Vasan RS; Mathias RA; Loos RJF; Rich SS; Lubitz SA; Heckbert SR; Redline S; Guo X; Chen Y-I; Laurie CA; Hernandez RD; McGarvey ST; Goddard ME; Laurie CC; North KE; Lange LA; Weir BS; Yengo L; Yang J; Visscher PM
Nat Genet; 2022 Mar; 54(3):263-273. PubMed ID: 35256806
[TBL] [Abstract][Full Text] [Related]
19. A genome-wide comparison of the functional properties of rare and common genetic variants in humans.
Zhu Q; Ge D; Maia JM; Zhu M; Petrovski S; Dickson SP; Heinzen EL; Shianna KV; Goldstein DB
Am J Hum Genet; 2011 Apr; 88(4):458-68. PubMed ID: 21457907
[TBL] [Abstract][Full Text] [Related]
20. Variance explained by whole genome sequence variants in coding and regulatory genome annotations for six dairy traits.
Koufariotis LT; Chen YP; Stothard P; Hayes BJ
BMC Genomics; 2018 Apr; 19(1):237. PubMed ID: 29618315
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
