BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 30300142)

  • 1. Temporal dynamics of Wnt-dependent transcriptome reveal an oncogenic Wnt/MYC/ribosome axis.
    Madan B; Harmston N; Nallan G; Montoya A; Faull P; Petretto E; Virshup DM
    J Clin Invest; 2018 Dec; 128(12):5620-5633. PubMed ID: 30300142
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PORCN inhibition synergizes with PI3K/mTOR inhibition in Wnt-addicted cancers.
    Zhong Z; Sepramaniam S; Chew XH; Wood K; Lee MA; Madan B; Virshup DM
    Oncogene; 2019 Oct; 38(40):6662-6677. PubMed ID: 31391551
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Porcupine Inhibition Disrupts Mitochondrial Function and Homeostasis in WNT Ligand-Addicted Pancreatic Cancer.
    Aguilera KY; Le T; Riahi R; Lay AR; Hinz S; Saadat EA; Vashisht AA; Wohlschlegel J; Donahue TR; Radu CG; Dawson DW
    Mol Cancer Ther; 2022 Jun; 21(6):936-947. PubMed ID: 35313331
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Widespread Repression of Gene Expression in Cancer by a Wnt/β-Catenin/MAPK Pathway.
    Harmston N; Lim JYS; Arqués O; Palmer HG; Petretto E; Virshup DM; Madan B
    Cancer Res; 2021 Jan; 81(2):464-475. PubMed ID: 33203702
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma.
    Li J; Wu G; Xu Y; Li J; Ruan N; Chen Y; Zhang Q; Xia Q
    Biomed Res Int; 2020; 2020():2527643. PubMed ID: 32104684
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma.
    Jiang X; Hao HX; Growney JD; Woolfenden S; Bottiglio C; Ng N; Lu B; Hsieh MH; Bagdasarian L; Meyer R; Smith TR; Avello M; Charlat O; Xie Y; Porter JA; Pan S; Liu J; McLaughlin ME; Cong F
    Proc Natl Acad Sci U S A; 2013 Jul; 110(31):12649-54. PubMed ID: 23847203
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel PORCN inhibitor WHN-88 targets Wnt/β-catenin pathway and prevents the growth of Wnt-driven cancers.
    Yang Q; Qin T; An T; Wu H; Xu G; Xiang J; Lei K; Zhang S; Xia J; Su G; Wang D; Xue M; Kong L; Zhang W; Wu S; Li Y
    Eur J Pharmacol; 2023 Apr; 945():175628. PubMed ID: 36858339
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine
    Rao DM; Shackleford MT; Bordeaux EK; Sottnik JL; Ferguson RL; Yamamoto TM; Wellberg EA; Bitler BG; Sikora MJ
    J Biol Chem; 2019 Dec; 294(52):19950-19966. PubMed ID: 31740580
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of WNT/β-Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61.
    Sano M; Driscoll DR; DeJesus-Monge WE; Quattrochi B; Appleman VA; Ou J; Zhu LJ; Yoshida N; Yamazaki S; Takayama T; Sugitani M; Nemoto N; Klimstra DS; Lewis BC
    Neoplasia; 2016 Dec; 18(12):785-794. PubMed ID: 27889647
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Epigenetic silencing of SFRP5 promotes the metastasis and invasion of chondrosarcoma by expression inhibition and Wnt signaling pathway activation.
    Sheng W; Zhang ZC; Shi DY; Wang BC; Wu Q; Shao ZW; Yang SH; He TC; Liu JX
    Chem Biol Interact; 2018 Dec; 296():1-8. PubMed ID: 30125549
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Deptor Is a Novel Target of Wnt/β-Catenin/c-Myc and Contributes to Colorectal Cancer Cell Growth.
    Wang Q; Zhou Y; Rychahou P; Harris JW; Zaytseva YY; Liu J; Wang C; Weiss HL; Liu C; Lee EY; Evers BM
    Cancer Res; 2018 Jun; 78(12):3163-3175. PubMed ID: 29666061
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SOX1 functions as a tumor suppressor by antagonizing the WNT/β-catenin signaling pathway in hepatocellular carcinoma.
    Tsao CM; Yan MD; Shih YL; Yu PN; Kuo CC; Lin WC; Li HJ; Lin YW
    Hepatology; 2012 Dec; 56(6):2277-87. PubMed ID: 22767186
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Wnt/β-catenin signaling pathway upregulates c-Myc expression to promote cell proliferation of P19 teratocarcinoma cells.
    Zhang S; Li Y; Wu Y; Shi K; Bing L; Hao J
    Anat Rec (Hoboken); 2012 Dec; 295(12):2104-13. PubMed ID: 22976998
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NOTUM is a potential pharmacodynamic biomarker of Wnt pathway inhibition.
    Madan B; Ke Z; Lei ZD; Oliver FA; Oshima M; Lee MA; Rozen S; Virshup DM
    Oncotarget; 2016 Mar; 7(11):12386-92. PubMed ID: 26848981
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MicroRNA-27a Promotes the Proliferation and Invasiveness of Colon Cancer Cells by Targeting SFRP1 through the Wnt/β-Catenin Signaling Pathway.
    Ba S; Xuan Y; Long ZW; Chen HY; Zheng SS
    Cell Physiol Biochem; 2017; 42(5):1920-1933. PubMed ID: 28772260
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitotic wnt signaling promotes protein stabilization and regulates cell size.
    Acebron SP; Karaulanov E; Berger BS; Huang YL; Niehrs C
    Mol Cell; 2014 May; 54(4):663-74. PubMed ID: 24837680
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation.
    Hao YH; Lafita-Navarro MC; Zacharias L; Borenstein-Auerbach N; Kim M; Barnes S; Kim J; Shay J; DeBerardinis RJ; Conacci-Sorrell M
    Cell Commun Signal; 2019 Oct; 17(1):129. PubMed ID: 31623618
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An
    Asciolla JJ; Miele MM; Hendrickson RC; Resh MD
    J Biol Chem; 2017 Aug; 292(33):13507-13513. PubMed ID: 28655768
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974.
    Liu J; Pan S; Hsieh MH; Ng N; Sun F; Wang T; Kasibhatla S; Schuller AG; Li AG; Cheng D; Li J; Tompkins C; Pferdekamper A; Steffy A; Cheng J; Kowal C; Phung V; Guo G; Wang Y; Graham MP; Flynn S; Brenner JC; Li C; Villarroel MC; Schultz PG; Wu X; McNamara P; Sellers WR; Petruzzelli L; Boral AL; Seidel HM; McLaughlin ME; Che J; Carey TE; Vanasse G; Harris JL
    Proc Natl Acad Sci U S A; 2013 Dec; 110(50):20224-9. PubMed ID: 24277854
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oncogenic MYC Induces the Impaired Ribosome Biogenesis Checkpoint and Stabilizes p53 Independent of Increased Ribosome Content.
    Morcelle C; Menoyo S; Morón-Duran FD; Tauler A; Kozma SC; Thomas G; Gentilella A
    Cancer Res; 2019 Sep; 79(17):4348-4359. PubMed ID: 31292158
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.