144 related articles for article (PubMed ID: 3030329)
1. In vitro metabolism of etoposide (VP-16-213) by liver microsomes and irreversible binding of reactive intermediates to microsomal proteins.
Haim N; Nemec J; Roman J; Sinha BK
Biochem Pharmacol; 1987 Feb; 36(4):527-36. PubMed ID: 3030329
[TBL] [Abstract][Full Text] [Related]
2. The role of metabolic activation by cytochrome P-450 in covalent binding of VP 16-213 to rat liver and HeLa cell microsomal proteins.
van Maanen JM; de Ruiter C; de Vries J; Kootstra PR; Gobas F; Pinedo HM
Eur J Cancer Clin Oncol; 1985 Sep; 21(9):1099-106. PubMed ID: 4065181
[TBL] [Abstract][Full Text] [Related]
3. Peroxidase-catalyzed metabolism of etoposide (VP-16-213) and covalent binding of reactive intermediates to cellular macromolecules.
Haim N; Nemec J; Roman J; Sinha BK
Cancer Res; 1987 Nov; 47(22):5835-40. PubMed ID: 3117357
[TBL] [Abstract][Full Text] [Related]
4. Mechanism for isaxonine hepatitis. I. Metabolic activation by mouse and human cytochrome P-450.
Lettéron P; Fouin-Fortunet H; Tinel M; Danan G; Belghiti J; Pessayre D
J Pharmacol Exp Ther; 1984 Jun; 229(3):845-50. PubMed ID: 6547179
[TBL] [Abstract][Full Text] [Related]
5. In vitro studies on the metabolism and covalent binding of [14C]1,1-dichloroethylene by mouse liver, kidney and lung.
Okine LK; Gram TE
Biochem Pharmacol; 1986 Aug; 35(16):2789-95. PubMed ID: 3741469
[TBL] [Abstract][Full Text] [Related]
6. Hepatic and pulmonary microsomal metabolism of naphthalene to glutathione adducts: factors affecting the relative rates of conjugate formation.
Buckpitt AR; Bahnson LS; Franklin RB
J Pharmacol Exp Ther; 1984 Nov; 231(2):291-300. PubMed ID: 6491983
[TBL] [Abstract][Full Text] [Related]
7. Metabolic activation of hydralazine by rat liver microsomes.
LaCagnin LB; Colby HD; Dalal NS; O'Donnell JP
Biochem Pharmacol; 1987 Aug; 36(16):2667-72. PubMed ID: 3038130
[TBL] [Abstract][Full Text] [Related]
8. Metabolic activation of 1,1-dichloroethylene by mouse lung and liver microsomes.
Forkert PG; Hofley M; Racz WJ
Can J Physiol Pharmacol; 1987 Jul; 65(7):1496-9. PubMed ID: 3664363
[TBL] [Abstract][Full Text] [Related]
9. Metabolic activation of lidocaine and covalent binding to rat liver microsomal protein.
Masubuchi Y; Araki J; Narimatsu S; Suzuki T
Biochem Pharmacol; 1992 Jun; 43(12):2551-7. PubMed ID: 1632813
[TBL] [Abstract][Full Text] [Related]
10. Metabolic activation of the tricyclic antidepressant amineptine--I. Cytochrome P-450-mediated in vitro covalent binding.
Geneve J; Larrey D; Letteron P; Descatoire V; Tinel M; Amouyal G; Pessayre D
Biochem Pharmacol; 1987 Feb; 36(3):323-9. PubMed ID: 3814174
[TBL] [Abstract][Full Text] [Related]
11. Cytochrome P-450-mediated O-demethylation: a route in the metabolic activation of etoposide (VP-16-213).
van Maanen JM; de Vries J; Pappie D; van den Akker E; Lafleur VM; Retèl J; van der Greef J; Pinedo HM
Cancer Res; 1987 Sep; 47(17):4658-62. PubMed ID: 3621161
[TBL] [Abstract][Full Text] [Related]
12. Semi-quinone formation from the catechol and ortho-quinone metabolites of the antitumor agent VP-16-213.
van Maanen JM; Verkerk UH; Broersen J; Lafleur MV; De Vries J; Retèl J; Pinedo HM
Free Radic Res Commun; 1988; 4(6):371-84. PubMed ID: 2854106
[TBL] [Abstract][Full Text] [Related]
13. Ascorbate is the primary reductant of the phenoxyl radical of etoposide in the presence of thiols both in cell homogenates and in model systems.
Kagan VE; Yalowich JC; Day BW; Goldman R; Gantchev TG; Stoyanovsky DA
Biochemistry; 1994 Aug; 33(32):9651-60. PubMed ID: 8068642
[TBL] [Abstract][Full Text] [Related]
14. Iron-dependent hydroxyl radical formation and DNA damage from a novel metabolite of the clinically active antitumor drug VP-16.
Sinha BK; Eliot HM; Kalayanaraman B
FEBS Lett; 1988 Jan; 227(2):240-4. PubMed ID: 2828121
[TBL] [Abstract][Full Text] [Related]
15. Monooxygenase-mediated activation of chlorotrianisene (TACE) in covalent binding to rat hepatic microsomal proteins.
Juedes MJ; Bulger WH; Kupfer D
Drug Metab Dispos; 1987; 15(6):786-93. PubMed ID: 2893703
[TBL] [Abstract][Full Text] [Related]
16. Oxidative activation of the thiophene ring by hepatic enzymes. Hydroxylation and formation of electrophilic metabolites during metabolism of tienilic acid and its isomer by rat liver microsomes.
Dansette PM; Amar C; Smith C; Pons C; Mansuy D
Biochem Pharmacol; 1990 Mar; 39(5):911-8. PubMed ID: 2310416
[TBL] [Abstract][Full Text] [Related]
17. Metabolic activation of the serotonergic neurotoxin para-chloroamphetamine to chemically reactive intermediates by hepatic and brain microsomal preparations.
Miller KJ; Anderholm DC; Ames MM
Biochem Pharmacol; 1986 May; 35(10):1737-42. PubMed ID: 3707603
[TBL] [Abstract][Full Text] [Related]
18. The covalent binding of cyclosporin A to rat liver macromolecules in vivo and in vitro: the role of cytochrome P-450.
Nagelkerke JF; Tijdens RB; Schwarz EP; Winters MF; Paul LC; Mulder GJ
Toxicology; 1987 Dec; 47(3):277-84. PubMed ID: 3424383
[TBL] [Abstract][Full Text] [Related]
19. In vivo and in vitro studies of the hepatotoxic effects of 4-chlorophenol in mice.
Phornchirasilp S; DeSouza JJ; Feller DR
Biochem Pharmacol; 1989 Mar; 38(6):961-72. PubMed ID: 2930597
[TBL] [Abstract][Full Text] [Related]
20. Relation between hepatic microsomal metabolism of N-nitrosamines and cytochrome P-450 species.
Kawanishi T; Ohno Y; Takahashi A; Takanaka A; Kasuya Y; Omori Y
Biochem Pharmacol; 1985 Apr; 34(7):919-24. PubMed ID: 3985997
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
