These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 30305425)

  • 21. Guanine-containing ssDNA and RNA induce dimeric and tetrameric structural forms of SAMHD1.
    Orris B; Sung MW; Bhat S; Xu Y; Huynh KW; Han S; Johnson DC; Bosbach B; Shields DJ; Stivers JT
    Nucleic Acids Res; 2023 Dec; 51(22):12443-12458. PubMed ID: 37930833
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Stabilization of SAMHD1 by NONO is crucial for Ara-C resistance in AML.
    Zhang F; Sun J; Tang X; Liang Y; Jiao Q; Yu B; Dai Z; Yuan X; Li J; Yan J; Zhang Z; Fan S; Wang M; Hu H; Zhang C; Lv XB
    Cell Death Dis; 2022 Jul; 13(7):590. PubMed ID: 35803902
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy.
    Rudd SG; Tsesmetzis N; Sanjiv K; Paulin CB; Sandhow L; Kutzner J; Hed Myrberg I; Bunten SS; Axelsson H; Zhang SM; Rasti A; Mäkelä P; Coggins SA; Tao S; Suman S; Branca RM; Mermelekas G; Wiita E; Lee S; Walfridsson J; Schinazi RF; Kim B; Lehtiö J; Rassidakis GZ; Pokrovskaja Tamm K; Warpman-Berglund U; Heyman M; Grandér D; Lehmann S; Lundbäck T; Qian H; Henter JI; Schaller T; Helleday T; Herold N
    EMBO Mol Med; 2020 Mar; 12(3):e10419. PubMed ID: 31950591
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Mechanism of allosteric activation of SAMHD1 by dGTP.
    Ji X; Wu Y; Yan J; Mehrens J; Yang H; DeLucia M; Hao C; Gronenborn AM; Skowronski J; Ahn J; Xiong Y
    Nat Struct Mol Biol; 2013 Nov; 20(11):1304-9. PubMed ID: 24141705
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Structural characterization and directed modification of Sus scrofa SAMHD1 reveal the mechanism underlying deoxynucleotide regulation.
    Kong J; Wang MM; He SY; Peng X; Qin XH
    FEBS J; 2019 Oct; 286(19):3844-3857. PubMed ID: 31152619
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Allosteric regulation of the human and mouse deoxyribonucleotide triphosphohydrolase sterile α-motif/histidine-aspartate domain-containing protein 1 (SAMHD1).
    Miazzi C; Ferraro P; Pontarin G; Rampazzo C; Reichard P; Bianchi V
    J Biol Chem; 2014 Jun; 289(26):18339-46. PubMed ID: 24828500
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A Cyclin-Binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation.
    St Gelais C; Kim SH; Maksimova VV; Buzovetsky O; Knecht KM; Shepard C; Kim B; Xiong Y; Wu L
    J Virol; 2018 Mar; 92(6):. PubMed ID: 29321329
    [TBL] [Abstract][Full Text] [Related]  

  • 28. SAMHD1 inhibits epithelial cell transformation in vitro and affects leukemia development in xenograft mice.
    Kodigepalli KM; Li M; Bonifati S; Panfil AR; Green PL; Liu SL; Wu L
    Cell Cycle; 2018; 17(23):2564-2576. PubMed ID: 30474474
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction.
    Arnold LH; Groom HC; Kunzelmann S; Schwefel D; Caswell SJ; Ordonez P; Mann MC; Rueschenbaum S; Goldstone DC; Pennell S; Howell SA; Stoye JP; Webb M; Taylor IA; Bishop KN
    PLoS Pathog; 2015 Oct; 11(10):e1005194. PubMed ID: 26431200
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells.
    Rothenburger T; Thomas D; Schreiber Y; Wratil PR; Pflantz T; Knecht K; Digianantonio K; Temple J; Schneider C; Baldauf HM; McLaughlin KM; Rothweiler F; Bilen B; Farmand S; Bojkova D; Costa R; Ferreirós N; Geisslinger G; Oellerich T; Xiong Y; Keppler OT; Wass MN; Michaelis M; Cinatl J
    J Exp Clin Cancer Res; 2021 Oct; 40(1):317. PubMed ID: 34641952
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Expression and Relationship of SAMHD1 with Other Apoptotic and Autophagic Genes in Acute Myeloid Leukemia Patients.
    Jiang H; Li C; Liu Z; Shengjing Hospital ;
    Acta Haematol; 2020; 143(1):51-59. PubMed ID: 31434075
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Impaired dNTPase activity of SAMHD1 by phosphomimetic mutation of Thr-592.
    Tang C; Ji X; Wu L; Xiong Y
    J Biol Chem; 2015 Oct; 290(44):26352-9. PubMed ID: 26294762
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Interplay of ancestral non-primate lentiviruses with the virus-restricting SAMHD1 proteins of their hosts.
    Mereby SA; Maehigashi T; Holler JM; Kim DH; Schinazi RF; Kim B
    J Biol Chem; 2018 Oct; 293(42):16402-16412. PubMed ID: 30181218
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML.
    Oellerich T; Schneider C; Thomas D; Knecht KM; Buzovetsky O; Kaderali L; Schliemann C; Bohnenberger H; Angenendt L; Hartmann W; Wardelmann E; Rothenburger T; Mohr S; Scheich S; Comoglio F; Wilke A; Ströbel P; Serve H; Michaelis M; Ferreirós N; Geisslinger G; Xiong Y; Keppler OT; Cinatl J
    Nat Commun; 2019 Aug; 10(1):3475. PubMed ID: 31375673
    [TBL] [Abstract][Full Text] [Related]  

  • 35. GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated state.
    Hansen EC; Seamon KJ; Cravens SL; Stivers JT
    Proc Natl Acad Sci U S A; 2014 May; 111(18):E1843-51. PubMed ID: 24753578
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Allosteric Activation of SAMHD1 Protein by Deoxynucleotide Triphosphate (dNTP)-dependent Tetramerization Requires dNTP Concentrations That Are Similar to dNTP Concentrations Observed in Cycling T Cells.
    Wang Z; Bhattacharya A; Villacorta J; Diaz-Griffero F; Ivanov DN
    J Biol Chem; 2016 Oct; 291(41):21407-21413. PubMed ID: 27566548
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structural Insights into the High-efficiency Catalytic Mechanism of the Sterile α-Motif/Histidine-Aspartate Domain-containing Protein.
    Li Y; Kong J; Peng X; Hou W; Qin X; Yu XF
    J Biol Chem; 2015 Dec; 290(49):29428-37. PubMed ID: 26438820
    [TBL] [Abstract][Full Text] [Related]  

  • 38. SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4
    Antonucci JM; Kim SH; St Gelais C; Bonifati S; Li TW; Buzovetsky O; Knecht KM; Duchon AA; Xiong Y; Musier-Forsyth K; Wu L
    J Virol; 2018 Aug; 92(15):. PubMed ID: 29793958
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Allosteric substrate activation of SAMHD1 shapes deoxynucleotide triphosphate imbalances by interconnecting the depletion and biosynthesis of different dNTPs.
    McCown C; Yu CH; Ivanov DN
    bioRxiv; 2023 Nov; ():. PubMed ID: 38014186
    [TBL] [Abstract][Full Text] [Related]  

  • 40. GTP is the primary activator of the anti-HIV restriction factor SAMHD1.
    Amie SM; Bambara RA; Kim B
    J Biol Chem; 2013 Aug; 288(35):25001-25006. PubMed ID: 23880768
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.