BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 30307162)

  • 1. Mechanisms of beneficial effects of metformin on fatty acid-treated human islets.
    Cen J; Sargsyan E; Forslund A; Bergsten P
    J Mol Endocrinol; 2018 Oct; 61(3):91-99. PubMed ID: 30307162
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of metformin on oxidative stress, adenine nucleotides balance, and glucose-induced insulin release impaired by chronic free fatty acids exposure in rat pancreatic islets.
    Piro S; Rabuazzo AM; Renis M; Purrello F
    J Endocrinol Invest; 2012 May; 35(5):504-10. PubMed ID: 21750398
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells.
    Simon-Szabó L; Kokas M; Mandl J; Kéri G; Csala M
    PLoS One; 2014; 9(6):e97868. PubMed ID: 24896641
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: a direct metformin effect on pancreatic beta-cells.
    Patanè G; Piro S; Rabuazzo AM; Anello M; Vigneri R; Purrello F
    Diabetes; 2000 May; 49(5):735-40. PubMed ID: 10905481
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Palmitate-Induced Insulin Hypersecretion and Later Secretory Decline Associated with Changes in Protein Expression Patterns in Human Pancreatic Islets.
    Groebe K; Cen J; Schvartz D; Sargsyan E; Chowdhury A; Roomp K; Schneider R; Alderborn A; Sanchez JC; Bergsten P
    J Proteome Res; 2018 Nov; 17(11):3824-3836. PubMed ID: 30183308
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Long term exposure to fatty acids and ketones inhibits B-cell functions in human pancreatic islets of Langerhans.
    Zhou YP; Grill V
    J Clin Endocrinol Metab; 1995 May; 80(5):1584-90. PubMed ID: 7745004
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Palmitate is not an effective fuel for pancreatic islets and amplifies insulin secretion independent of calcium release from endoplasmic reticulum.
    Kuok IT; Rountree AM; Jung SR; Sweet IR
    Islets; 2019; 11(3):51-64. PubMed ID: 31084524
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lipotoxicity in human pancreatic islets and the protective effect of metformin.
    Lupi R; Del Guerra S; Fierabracci V; Marselli L; Novelli M; Patanè G; Boggi U; Mosca F; Piro S; Del Prato S; Marchetti P
    Diabetes; 2002 Feb; 51 Suppl 1():S134-7. PubMed ID: 11815472
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets.
    Ladrière L; Igoillo-Esteve M; Cunha DA; Brion JP; Bugliani M; Marchetti P; Eizirik DL; Cnop M
    J Clin Endocrinol Metab; 2010 Mar; 95(3):1442-9. PubMed ID: 20080856
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metformin regulates palmitate-induced apoptosis and ER stress response in HepG2 liver cells.
    Kim DS; Jeong SK; Kim HR; Kim DS; Chae SW; Chae HJ
    Immunopharmacol Immunotoxicol; 2010 Jun; 32(2):251-7. PubMed ID: 20038265
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion.
    Leclerc I; Woltersdorf WW; da Silva Xavier G; Rowe RL; Cross SE; Korbutt GS; Rajotte RV; Smith R; Rutter GA
    Am J Physiol Endocrinol Metab; 2004 Jun; 286(6):E1023-31. PubMed ID: 14871885
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metformin Ameliorates Lipotoxic β-Cell Dysfunction through a Concentration-Dependent Dual Mechanism of Action.
    Kim HI; Lee JS; Kwak BK; Hwang WM; Kim MJ; Kim YB; Chung SS; Park KS
    Diabetes Metab J; 2019 Dec; 43(6):854-866. PubMed ID: 31339010
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Palmitic acid-rich diet suppresses glucose-stimulated insulin secretion (GSIS) and induces endoplasmic reticulum (ER) stress in pancreatic islets in mice.
    Hirata T; Kawai T; Hirose H; Tanaka K; Kurosawa H; Fujii C; Fujita H; Seto Y; Matsumoto H; Itoh H
    Endocr Res; 2016; 41(1):8-15. PubMed ID: 26167855
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role and mechanism of rosiglitazone on the impairment of insulin secretion induced by free fatty acids on isolated rat islets.
    Tian JY; Li G; Gu YY; Zhang HL; Zhou WZ; Wang X; Zhu HD; Luo TH; Luo M
    Chin Med J (Engl); 2006 Apr; 119(7):574-80. PubMed ID: 16620699
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pioglitazone acutely reduces insulin secretion and causes metabolic deceleration of the pancreatic beta-cell at submaximal glucose concentrations.
    Lamontagne J; Pepin E; Peyot ML; Joly E; Ruderman NB; Poitout V; Madiraju SR; Nolan CJ; Prentki M
    Endocrinology; 2009 Aug; 150(8):3465-74. PubMed ID: 19406947
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metformin Can Attenuate Beta-Cell Hypersecretion-Implications for Treatment of Children with Obesity.
    Wen Q; Stenlid R; Chowdhury AI; Ciba I; Aydin B; Cerenius SY; Manell H; Forslund A; Bergsten P
    Metabolites; 2023 Aug; 13(8):. PubMed ID: 37623862
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression.
    Joseph JW; Koshkin V; Saleh MC; Sivitz WI; Zhang CY; Lowell BB; Chan CB; Wheeler MB
    J Biol Chem; 2004 Dec; 279(49):51049-56. PubMed ID: 15448158
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metformin restores prohormone processing enzymes and normalizes aberrations in secretion of proinsulin and insulin in palmitate-exposed human islets.
    Wen Q; Chowdhury AI; Aydin B; Shekha M; Stenlid R; Forslund A; Bergsten P
    Diabetes Obes Metab; 2023 Dec; 25(12):3757-3765. PubMed ID: 37694762
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modulation of Autophagy Influences the Function and Survival of Human Pancreatic Beta Cells Under Endoplasmic Reticulum Stress Conditions and in Type 2 Diabetes.
    Bugliani M; Mossuto S; Grano F; Suleiman M; Marselli L; Boggi U; De Simone P; Eizirik DL; Cnop M; Marchetti P; De Tata V
    Front Endocrinol (Lausanne); 2019; 10():52. PubMed ID: 30863363
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The biguanide compound metformin prevents desensitization of human pancreatic islets induced by high glucose.
    Lupi R; Del Guerra S; Tellini C; Giannarelli R; Coppelli A; Lorenzetti M; Carmellini M; Mosca F; Navalesi R; Marchetti P
    Eur J Pharmacol; 1999 Jan; 364(2-3):205-9. PubMed ID: 9932725
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.