BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

665 related articles for article (PubMed ID: 30312685)

  • 1. Interactions between acetylcholinesterase, toxic organophosphorus compounds and a short series of structurally related non-oxime reactivators: Analysis of reactivation and inhibition kinetics in vitro.
    Horn G; de Koning MC; van Grol M; Thiermann H; Worek F
    Toxicol Lett; 2018 Dec; 299():218-225. PubMed ID: 30312685
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase.
    Bartling A; Worek F; Szinicz L; Thiermann H
    Toxicology; 2007 Apr; 233(1-3):166-72. PubMed ID: 16904809
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A common mechanism for resistance to oxime reactivation of acetylcholinesterase inhibited by organophosphorus compounds.
    Maxwell DM; Brecht KM; Sweeney RE
    Chem Biol Interact; 2013 Mar; 203(1):72-6. PubMed ID: 22982773
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase.
    Winter M; Wille T; Musilek K; Kuca K; Thiermann H; Worek F
    Toxicol Lett; 2016 Feb; 244():136-142. PubMed ID: 26210933
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of reversible ligands on oxime-induced reactivation of sarin- and cyclosarin-inhibited human acetylcholinesterase.
    Scheffel C; Thiermann H; Worek F
    Toxicol Lett; 2015 Feb; 232(3):557-65. PubMed ID: 25522658
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reactivation kinetics of a homologous series of bispyridinium bis-oximes with nerve agent-inhibited human acetylcholinesterase.
    Worek F; von der Wellen J; Musilek K; Kuca K; Thiermann H
    Arch Toxicol; 2012 Sep; 86(9):1379-86. PubMed ID: 22437842
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction of pentylsarin analogues with human acetylcholinesterase: a kinetic study.
    Worek F; Herkert NM; Koller M; Aurbek N; Thiermann H
    Toxicol Lett; 2009 Jun; 187(2):119-23. PubMed ID: 19429253
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates.
    Worek F; Reiter G; Eyer P; Szinicz L
    Arch Toxicol; 2002 Sep; 76(9):523-9. PubMed ID: 12242610
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural requirements for effective oximes--evaluation of kinetic in vitro data with phosphylated human AChE and structurally different oximes.
    Worek F; Wille T; Koller M; Thiermann H
    Chem Biol Interact; 2013 Mar; 203(1):125-8. PubMed ID: 22827894
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reactivation kinetics of a series of related bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase--Structure-activity relationships.
    Worek F; Wille T; Koller M; Thiermann H
    Biochem Pharmacol; 2012 Jun; 83(12):1700-6. PubMed ID: 22649796
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oxime-mediated in vitro reactivation kinetic analysis of organophosphates-inhibited human and electric eel acetylcholinesterase.
    Sahu AK; Sharma R; Gupta B; Musilek K; Kuca K; Acharya J; Ghosh KK
    Toxicol Mech Methods; 2016 Jun; 26(5):319-26. PubMed ID: 27101948
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro.
    Worek F; Aurbek N; Thiermann H
    J Appl Toxicol; 2007; 27(6):582-8. PubMed ID: 17370251
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents.
    Cadieux CL; Wang H; Zhang Y; Koenig JA; Shih TM; McDonough J; Koh J; Cerasoli D
    Chem Biol Interact; 2016 Nov; 259(Pt B):133-141. PubMed ID: 27062893
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparative study of oxime-induced reactivation of erythrocyte and muscle AChE from different animal species following inhibition by sarin or paraoxon.
    Herkert NM; Aurbek N; Eyer P; Thiermann H; Worek F
    Toxicol Lett; 2010 May; 194(3):94-101. PubMed ID: 20156534
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinetic analysis of interactions of amodiaquine with human cholinesterases and organophosphorus compounds.
    Bierwisch A; Wille T; Thiermann H; Worek F
    Toxicol Lett; 2016 Mar; 246():49-56. PubMed ID: 26851641
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of a potent non-oxime reactivator of nerve agent inhibited human acetylcholinesterase.
    de Koning MC; Horn G; Worek F; van Grol M
    Eur J Med Chem; 2018 Sep; 157():151-160. PubMed ID: 30096649
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reactivation of organophosphate-inhibited human acetylcholinesterase by isonitrosoacetone (MINA): a kinetic analysis.
    Worek F; Thiermann H
    Chem Biol Interact; 2011 Nov; 194(2-3):91-6. PubMed ID: 21930118
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds with human and pig acetylcholinesterase.
    Aurbek N; Thiermann H; Szinicz L; Eyer P; Worek F
    Toxicology; 2006 Jul; 224(1-2):91-9. PubMed ID: 16720069
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Kinetic analysis of interactions of different sarin and tabun analogues with human acetylcholinesterase and oximes: is there a structure-activity relationship?
    Aurbek N; Herkert NM; Koller M; Thiermann H; Worek F
    Chem Biol Interact; 2010 Sep; 187(1-3):215-9. PubMed ID: 20105433
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reactivation of organophosphate-inhibited human, Cynomolgus monkey, swine and guinea pig acetylcholinesterase by MMB-4: a modified kinetic approach.
    Worek F; Wille T; Aurbek N; Eyer P; Thiermann H
    Toxicol Appl Pharmacol; 2010 Dec; 249(3):231-7. PubMed ID: 20888357
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.