BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 30320358)

  • 1. Hypoxia increases chemoresistance in human medulloblastoma DAOY cells via hypoxia‑inducible factor 1α‑mediated downregulation of the CYP2B6, CYP3A4 and CYP3A5 enzymes and inhibition of cell proliferation.
    Valencia-Cervantes J; Huerta-Yepez S; Aquino-Jarquín G; Rodríguez-Enríquez S; Martínez-Fong D; Arias-Montaño JA; Dávila-Borja VM
    Oncol Rep; 2019 Jan; 41(1):178-190. PubMed ID: 30320358
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Downregulation of CYP1A2, CYP2B6, and CYP3A4 in Human Hepatocytes by Prolyl Hydroxylase Domain 2 Inhibitors via Hypoxia-Inducible Factor-
    Takano H; Yamaguchi JI; Kato S; Hamada M; Tada M; Endo H
    Drug Metab Dispos; 2021 Jan; 49(1):20-30. PubMed ID: 33087449
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enantioselective metabolism and cytotoxicity of R-ifosfamide and S-ifosfamide by tumor cell-expressed cytochromes P450.
    Chen CS; Jounaidi Y; Waxman DJ
    Drug Metab Dispos; 2005 Sep; 33(9):1261-7. PubMed ID: 15919850
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of the anticancer drugs cyclophosphamide and ifosfamide by cytochrome P450 BM3 mutants.
    Vredenburg G; den Braver-Sewradj S; van Vugt-Lussenburg BM; Vermeulen NP; Commandeur JN; Vos JC
    Toxicol Lett; 2015 Jan; 232(1):182-92. PubMed ID: 25448283
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles.
    Roy P; Yu LJ; Crespi CL; Waxman DJ
    Drug Metab Dispos; 1999 Jun; 27(6):655-66. PubMed ID: 10348794
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Combination of clotam and vincristine enhances anti-proliferative effect in medulloblastoma cells.
    Patil S; Sankpal UT; Hurtado M; Bowman WP; Murray J; Borgmann K; Ghorpade A; Sutphin R; Eslin D; Basha R
    Gene; 2019 Jul; 705():67-76. PubMed ID: 30991098
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ginsenoside Rh2 inhibits proliferation and migration of medulloblastoma Daoy by down-regulation of microRNA-31.
    Chen Y; Shang H; Zhang S; Zhang X
    J Cell Biochem; 2018 Aug; 119(8):6527-6534. PubMed ID: 29377269
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [MicroRNA383 regulates expression of PRDX3 in human medulloblastomas].
    Wang XM; Zhang SF; Cheng ZQ; Peng QZ; Hu JT; Gao LK; Xu J; Jin HT; Liu HY
    Zhonghua Bing Li Xue Za Zhi; 2012 Aug; 41(8):547-52. PubMed ID: 23157748
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Retroviral transfer of human cytochrome P450 genes for oxazaphosphorine-based cancer gene therapy.
    Jounaidi Y; Hecht JE; Waxman DJ
    Cancer Res; 1998 Oct; 58(19):4391-401. PubMed ID: 9766669
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The effect of alpha-v integrin inhibition on the malignant characteristics of medulloblastoma.
    Thompson EM; Whitney NL; Wu YJ; Neuwelt EA
    J Neurosurg Pediatr; 2013 Jan; 11(1):60-7. PubMed ID: 23082872
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sensitization of human breast cancer cells to cyclophosphamide and ifosfamide by transfer of a liver cytochrome P450 gene.
    Chen L; Waxman DJ; Chen D; Kufe DW
    Cancer Res; 1996 Mar; 56(6):1331-40. PubMed ID: 8640822
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lutein inhibits proliferation, invasion and migration of hypoxic breast cancer cells via downregulation of HES1.
    Li Y; Zhang Y; Liu X; Wang M; Wang P; Yang J; Zhang S
    Int J Oncol; 2018 Jun; 52(6):2119-2129. PubMed ID: 29620169
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hypoxia‑inducible factor 1α and ROCK1 regulate proliferation and collagen synthesis in hepatic stellate cells under hypoxia.
    Hu Y; Hu D; Yu H; Xu W; Fu R
    Mol Med Rep; 2018 Oct; 18(4):3997-4003. PubMed ID: 30132575
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stereoselective metabolism of ifosfamide by human P-450s 3A4 and 2B6. Favorable metabolic properties of R-enantiomer.
    Roy P; Tretyakov O; Wright J; Waxman DJ
    Drug Metab Dispos; 1999 Nov; 27(11):1309-18. PubMed ID: 10534317
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HIF1A is Overexpressed in Medulloblastoma and its Inhibition Reduces Proliferation and Increases EPAS1 and ATG16L1 Methylation.
    Cruzeiro GAV; Dos Reis MB; Silveira VS; Lira RCP; Carlotti CG; Neder L; Oliveira RS; Yunes JA; Brandalise SR; Aguiar S; Eterovic AK; Tone LG; Scrideli CA; Valera ET
    Curr Cancer Drug Targets; 2018; 18(3):287-294. PubMed ID: 28302031
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The hypoxia-mimetic agent CoCl₂ induces chemotherapy resistance in LOVO colorectal cancer cells.
    Yang G; Xu S; Peng L; Li H; Zhao Y; Hu Y
    Mol Med Rep; 2016 Mar; 13(3):2583-9. PubMed ID: 26846577
    [TBL] [Abstract][Full Text] [Related]  

  • 17. All-trans-retinoic acid induces cell growth arrest in a human medulloblastoma cell line.
    Chang Q; Chen Z; You J; McNutt MA; Zhang T; Han Z; Zhang X; Gong E; Gu J
    J Neurooncol; 2007 Sep; 84(3):263-7. PubMed ID: 17453147
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antidepressant hyperforin up-regulates VEGF in CNS tumour cells.
    Tassone E; Maran C; Masola V; Bradaschia A; Garbisa S; Onisto M
    Pharmacol Res; 2011 Jan; 63(1):37-43. PubMed ID: 20883786
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Drug-metabolising enzymes are down-regulated by hypoxia in differentiated human hepatoma HepaRG cells: HIF-1alpha involvement in CYP3A4 repression.
    Legendre C; Hori T; Loyer P; Aninat C; Ishida S; Glaise D; Lucas-Clerc C; Boudjema K; Guguen-Guillouzo C; Corlu A; Morel F
    Eur J Cancer; 2009 Nov; 45(16):2882-92. PubMed ID: 19695866
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Downregulation of hypoxia‑inducible factor-1α inhibits growth, invasion, and angiogenesis of human salivary adenoid cystic carcinoma cells under hypoxia.
    Xiao C; Pan Y; Zeng X; Wang L; Li Z; Yan S; Wang H
    Oncol Rep; 2018 Sep; 40(3):1675-1683. PubMed ID: 30015895
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.