These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 30321816)

  • 1. Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model.
    Luo F; Xie Y; Wang Z; Huang J; Tan Q; Sun X; Li F; Li C; Liu M; Zhang D; Xu M; Su N; Ni Z; Jiang W; Chang J; Chen H; Chen S; Xu X; Deng C; Wang Z; Du X; Chen L
    Mol Ther Nucleic Acids; 2018 Dec; 13():291-302. PubMed ID: 30321816
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis.
    Yin L; Du X; Li C; Xu X; Chen Z; Su N; Zhao L; Qi H; Li F; Xue J; Yang J; Jin M; Deng C; Chen L
    Bone; 2008 Apr; 42(4):631-43. PubMed ID: 18242159
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2(+P253R) mice.
    Wang Y; Sun M; Uhlhorn VL; Zhou X; Peter I; Martinez-Abadias N; Hill CA; Percival CJ; Richtsmeier JT; Huso DL; Jabs EW
    BMC Dev Biol; 2010 Feb; 10():22. PubMed ID: 20175913
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deformed Skull Morphology Is Caused by the Combined Effects of the Maldevelopment of Calvarias, Cranial Base and Brain in FGFR2-P253R Mice Mimicking Human Apert Syndrome.
    Luo F; Xie Y; Xu W; Huang J; Zhou S; Wang Z; Luo X; Liu M; Chen L; Du X
    Int J Biol Sci; 2017; 13(1):32-45. PubMed ID: 28123344
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activating (P253R, C278F) and dominant negative mutations of FGFR2: differential effects on calvarial bone cell proliferation, differentiation, and mineralization.
    Ratisoontorn C; Fan GF; McEntee K; Nah HD
    Connect Tissue Res; 2003; 44 Suppl 1():292-7. PubMed ID: 12952211
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Exosome-mediated small interfering RNA delivery inhibits aberrant osteoblast differentiation in Apert syndrome model mice.
    Myo AC; Kobayashi Y; Niki Y; Kamimoto H; Moriyama K
    Arch Oral Biol; 2023 Sep; 153():105753. PubMed ID: 37348363
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dynamic morphological changes in the skulls of mice mimicking human Apert syndrome resulting from gain-of-function mutation of FGFR2 (P253R).
    Du X; Weng T; Sun Q; Su N; Chen Z; Qi H; Jin M; Yin L; He Q; Chen L
    J Anat; 2010 Aug; 217(2):97-105. PubMed ID: 20557404
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Negative autoregulation of fibroblast growth factor receptor 2 expression characterizing cranial development in cases of Apert (P253R mutation) and Pfeiffer (C278F mutation) syndromes and suggesting a basis for differences in their cranial phenotypes.
    Britto JA; Moore RL; Evans RD; Hayward RD; Jones BM
    J Neurosurg; 2001 Oct; 95(4):660-73. PubMed ID: 11596961
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dura in the pathogenesis of syndromic craniosynostosis: fibroblast growth factor receptor 2 mutations in dural cells promote osteogenic proliferation and differentiation of osteoblasts.
    Ang BU; Spivak RM; Nah HD; Kirschner RE
    J Craniofac Surg; 2010 Mar; 21(2):462-7. PubMed ID: 20489451
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Beyond the closed suture in apert syndrome mouse models: evidence of primary effects of FGFR2 signaling on facial shape at birth.
    Martínez-Abadías N; Percival C; Aldridge K; Hill CA; Ryan T; Sirivunnabood S; Wang Y; Jabs EW; Richtsmeier JT
    Dev Dyn; 2010 Nov; 239(11):3058-71. PubMed ID: 20842696
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis.
    Shukla V; Coumoul X; Wang RH; Kim HS; Deng CX
    Nat Genet; 2007 Sep; 39(9):1145-50. PubMed ID: 17694057
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Soluble form of FGFR2 with S252W partially prevents craniosynostosis of the apert mouse model.
    Morita J; Nakamura M; Kobayashi Y; Deng CX; Funato N; Moriyama K
    Dev Dyn; 2014 Apr; 243(4):560-7. PubMed ID: 24259495
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mandibular dysmorphology due to abnormal embryonic osteogenesis in FGFR2-related craniosynostosis mice.
    Motch Perrine SM; Wu M; Stephens NB; Kriti D; van Bakel H; Jabs EW; Richtsmeier JT
    Dis Model Mech; 2019 May; 12(5):. PubMed ID: 31064775
    [TBL] [Abstract][Full Text] [Related]  

  • 14. From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome.
    Martínez-Abadías N; Holmes G; Pankratz T; Wang Y; Zhou X; Jabs EW; Richtsmeier JT
    Dis Model Mech; 2013 May; 6(3):768-79. PubMed ID: 23519026
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis.
    Yokota M; Kobayashi Y; Morita J; Suzuki H; Hashimoto Y; Sasaki Y; Akiyoshi K; Moriyama K
    PLoS One; 2014; 9(7):e101693. PubMed ID: 25003957
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tripod-shaped Syndactyly in Apert Syndrome with FGFR2 p.P253R Mutation.
    Singh CB; Mishra B; Patel R; Kumar A; Ali A
    Indian J Plast Surg; 2021 Sep; 54(3):370-372. PubMed ID: 34667527
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Ser252Trp [corrected] substitution in mouse fibroblast growth factor receptor 2 (Fgfr2) results in craniosynostosis.
    Chen L; Li D; Li C; Engel A; Deng CX
    Bone; 2003 Aug; 33(2):169-78. PubMed ID: 14499350
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PIN1 Attenuation Improves Midface Hypoplasia in a Mouse Model of Apert Syndrome.
    Kim B; Shin H; Kim W; Kim H; Cho Y; Yoon H; Baek J; Woo K; Lee Y; Ryoo H
    J Dent Res; 2020 Feb; 99(2):223-232. PubMed ID: 31869252
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts.
    Mansukhani A; Bellosta P; Sahni M; Basilico C
    J Cell Biol; 2000 Jun; 149(6):1297-308. PubMed ID: 10851026
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The primary site of the acrocephalic feature in Apert Syndrome is a dwarf cranial base with accelerated chondrocytic differentiation due to aberrant activation of the FGFR2 signaling.
    Nagata M; Nuckolls GH; Wang X; Shum L; Seki Y; Kawase T; Takahashi K; Nonaka K; Takahashi I; Noman AA; Suzuki K; Slavkin HC
    Bone; 2011 Apr; 48(4):847-56. PubMed ID: 21129456
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.