323 related articles for article (PubMed ID: 3032421)
1. Role of metabolism and oxidation-reduction cycling in the cytotoxicity of antitumor quinoneimines and quinonediimines.
Powis G; Hodnett EM; Santone KS; See KL; Melder DC
Cancer Res; 1987 May; 47(9):2363-70. PubMed ID: 3032421
[TBL] [Abstract][Full Text] [Related]
2. Quinoneimines as substrates for quinone reductase (NAD(P)H: (quinone-acceptor)oxidoreductase) and the effect of dicumarol on their cytotoxicity.
Powis G; See KL; Santone KS; Melder DC; Hodnett EM
Biochem Pharmacol; 1987 Aug; 36(15):2473-9. PubMed ID: 2440444
[TBL] [Abstract][Full Text] [Related]
3. Comparative cytotoxic effects of N-acetyl-p-benzoquinone imine and two dimethylated analogues.
Rundgren M; Porubek DJ; Harvison PJ; Cotgreave IA; Moldéus P; Nelson SD
Mol Pharmacol; 1988 Oct; 34(4):566-72. PubMed ID: 3173335
[TBL] [Abstract][Full Text] [Related]
4. Reduction and glutathione conjugation reactions of N-acetyl-p-benzoquinone imine and two dimethylated analogues.
Rosen GM; Rauckman EJ; Ellington SP; Dahlin DC; Christie JL; Nelson SD
Mol Pharmacol; 1984 Jan; 25(1):151-7. PubMed ID: 6323948
[TBL] [Abstract][Full Text] [Related]
5. Nicotinamide adenine dinucleotide (phosphate): quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumor quinones: quinone cytotoxicity and selectivity in human lung and breast cancer cell lines.
Beall HD; Murphy AM; Siegel D; Hargreaves RH; Butler J; Ross D
Mol Pharmacol; 1995 Sep; 48(3):499-504. PubMed ID: 7565631
[TBL] [Abstract][Full Text] [Related]
6. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
Beland FA
Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
[TBL] [Abstract][Full Text] [Related]
7. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
Fourie J; Oleschuk CJ; Guziec F; Guziec L; Fiterman DJ; Monterrosa C; Begleiter A
Cancer Chemother Pharmacol; 2002 Feb; 49(2):101-10. PubMed ID: 11862423
[TBL] [Abstract][Full Text] [Related]
8. Modulation of trenimon-induced cytotoxicity by DT-diaphorase in isolated rat hepatocytes under aerobic versus hypoxic conditions.
Silva JM; Rao DN; O'Brien PJ
Cancer Res; 1992 Jun; 52(11):3015-21. PubMed ID: 1375532
[TBL] [Abstract][Full Text] [Related]
9. Mechanism for the hepatotoxicity of the antiandrogen, nilutamide. Evidence suggesting that redox cycling of this nitroaromatic drug leads to oxidative stress in isolated hepatocytes.
Fau D; Berson A; Eugene D; Fromenty B; Fisch C; Pessayre D
J Pharmacol Exp Ther; 1992 Oct; 263(1):69-77. PubMed ID: 1403804
[TBL] [Abstract][Full Text] [Related]
10. Generation of free radicals during the reductive metabolism of the nitroaromatic compound, nilutamide.
Berson A; Wolf C; Berger V; Fau D; Chachaty C; Fromenty B; Pessayre D
J Pharmacol Exp Ther; 1991 May; 257(2):714-9. PubMed ID: 1851835
[TBL] [Abstract][Full Text] [Related]
11. The metabolism of N-acetyl-3,5-dimethyl-p-benzoquinone imine in isolated hepatocytes involves N-deacetylation.
Rossi L; McGirr LG; Silva J; O'Brien PJ
Mol Pharmacol; 1988 Nov; 34(5):674-81. PubMed ID: 3193958
[TBL] [Abstract][Full Text] [Related]
12. Oxidative metabolism of combretastatin A-1 produces quinone intermediates with the potential to bind to nucleophiles and to enhance oxidative stress via free radicals.
Folkes LK; Christlieb M; Madej E; Stratford MR; Wardman P
Chem Res Toxicol; 2007 Dec; 20(12):1885-94. PubMed ID: 17941699
[TBL] [Abstract][Full Text] [Related]
13. The role of NAD(P)H:quinone oxidoreductase in quinone-mediated p21 induction in human colon carcinoma cells.
Qiu XB; Cadenas E
Arch Biochem Biophys; 1997 Oct; 346(2):241-51. PubMed ID: 9343371
[TBL] [Abstract][Full Text] [Related]
14. Benzo[a]pyrene dione-benzo[a]pyrene diol oxidation-reduction couples; involvement in DNA damage, cellular toxicity, and carcinogenesis.
Lesko SA; Lorentzen RJ
J Toxicol Environ Health; 1985; 16(5):679-91. PubMed ID: 3005601
[TBL] [Abstract][Full Text] [Related]
15. Free radicals in quinone-containing antitumor agents. Electrochemical reduction of diaziquone (2,5-diaziridine-3,6-bis(carboethoxyamino)-1,4 -benzoquinone) and two analogues.
Gutierrez PL; Fox BM; Mossoba MM; Bachur NR
Mol Pharmacol; 1984 Nov; 26(3):582-6. PubMed ID: 6092903
[TBL] [Abstract][Full Text] [Related]
16. An examination of quinone toxicity using the yeast Saccharomyces cerevisiae model system.
Rodriguez CE; Shinyashiki M; Froines J; Yu RC; Fukuto JM; Cho AK
Toxicology; 2004 Sep; 201(1-3):185-96. PubMed ID: 15297032
[TBL] [Abstract][Full Text] [Related]
17. Oxygen consumption and oxyradical production from microsomal reduction of aqueous extracts of cigarette tar.
Winston GW; Church DF; Cueto R; Pryor WA
Arch Biochem Biophys; 1993 Aug; 304(2):371-8. PubMed ID: 8394056
[TBL] [Abstract][Full Text] [Related]
18. NRH:quinone oxidoreductase 2 (NQO2) catalyzes metabolic activation of quinones and anti-tumor drugs.
Celli CM; Tran N; Knox R; Jaiswal AK
Biochem Pharmacol; 2006 Jul; 72(3):366-76. PubMed ID: 16765324
[TBL] [Abstract][Full Text] [Related]
19. Novel quinolinequinone antitumor agents: structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1).
Fryatt T; Pettersson HI; Gardipee WT; Bray KC; Green SJ; Slawin AM; Beall HD; Moody CJ
Bioorg Med Chem; 2004 Apr; 12(7):1667-87. PubMed ID: 15028260
[TBL] [Abstract][Full Text] [Related]
20. Characterization of a set of Chinese hamster ovary variant cell lines demonstrating differing sensitivity to mitomycin C.
Kuehl BL; Buchwald M; Rauth AM
Oncol Res; 1993; 5(6-7):213-21. PubMed ID: 8123941
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
