638 related articles for article (PubMed ID: 30327977)
1. Calpain Inhibition Increases SMN Protein in Spinal Cord Motoneurons and Ameliorates the Spinal Muscular Atrophy Phenotype in Mice.
de la Fuente S; Sansa A; Periyakaruppiah A; Garcera A; Soler RM
Mol Neurobiol; 2019 Jun; 56(6):4414-4427. PubMed ID: 30327977
[TBL] [Abstract][Full Text] [Related]
2. Calpain system is altered in survival motor neuron-reduced cells from in vitro and in vivo spinal muscular atrophy models.
de la Fuente S; Sansa A; Hidalgo I; Vivancos N; Romero-Guevara R; Garcera A; Soler RM
Cell Death Dis; 2020 Jun; 11(6):487. PubMed ID: 32587237
[TBL] [Abstract][Full Text] [Related]
3. The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy.
Monani UR; Sendtner M; Coovert DD; Parsons DW; Andreassi C; Le TT; Jablonka S; Schrank B; Rossoll W; Prior TW; Morris GE; Burghes AH
Hum Mol Genet; 2000 Feb; 9(3):333-9. PubMed ID: 10655541
[TBL] [Abstract][Full Text] [Related]
4. Survival motor neuron protein reduction deregulates autophagy in spinal cord motoneurons in vitro.
Garcera A; Bahi N; Periyakaruppiah A; Arumugam S; Soler RM
Cell Death Dis; 2013 Jun; 4(6):e686. PubMed ID: 23788043
[TBL] [Abstract][Full Text] [Related]
5. Loganin possesses neuroprotective properties, restores SMN protein and activates protein synthesis positive regulator Akt/mTOR in experimental models of spinal muscular atrophy.
Tseng YT; Chen CS; Jong YJ; Chang FR; Lo YC
Pharmacol Res; 2016 Sep; 111():58-75. PubMed ID: 27241020
[TBL] [Abstract][Full Text] [Related]
6. Modeling the differential phenotypes of spinal muscular atrophy with high-yield generation of motor neurons from human induced pluripotent stem cells.
Lin X; Li JJ; Qian WJ; Zhang QJ; Wang ZF; Lu YQ; Dong EL; He J; Wang N; Ma LX; Chen WJ
Oncotarget; 2017 Jun; 8(26):42030-42042. PubMed ID: 28159932
[TBL] [Abstract][Full Text] [Related]
7. Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model.
Hua Y; Sahashi K; Rigo F; Hung G; Horev G; Bennett CF; Krainer AR
Nature; 2011 Oct; 478(7367):123-6. PubMed ID: 21979052
[TBL] [Abstract][Full Text] [Related]
8. A new model to study spinal muscular atrophy: neurite degeneration and cell death is counteracted by BCL-X(L) Overexpression in motoneurons.
Garcera A; Mincheva S; Gou-Fabregas M; Caraballo-Miralles V; Lladó J; Comella JX; Soler RM
Neurobiol Dis; 2011 Jun; 42(3):415-26. PubMed ID: 21333739
[TBL] [Abstract][Full Text] [Related]
9. SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy.
Riessland M; Ackermann B; Förster A; Jakubik M; Hauke J; Garbes L; Fritzsche I; Mende Y; Blumcke I; Hahnen E; Wirth B
Hum Mol Genet; 2010 Apr; 19(8):1492-506. PubMed ID: 20097677
[TBL] [Abstract][Full Text] [Related]
10. The zinc finger protein ZPR1 is a potential modifier of spinal muscular atrophy.
Ahmad S; Wang Y; Shaik GM; Burghes AH; Gangwani L
Hum Mol Genet; 2012 Jun; 21(12):2745-58. PubMed ID: 22422766
[TBL] [Abstract][Full Text] [Related]
11. ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy.
Kannan A; Jiang X; He L; Ahmad S; Gangwani L
Brain; 2020 Jan; 143(1):69-93. PubMed ID: 31828288
[TBL] [Abstract][Full Text] [Related]
12. Reduced survival of motor neuron (SMN) protein in motor neuronal progenitors functions cell autonomously to cause spinal muscular atrophy in model mice expressing the human centromeric (SMN2) gene.
Park GH; Maeno-Hikichi Y; Awano T; Landmesser LT; Monani UR
J Neurosci; 2010 Sep; 30(36):12005-19. PubMed ID: 20826664
[TBL] [Abstract][Full Text] [Related]
13. Hypothermia improves disease manifestations in SMA mice via SMN augmentation.
Tsai LK; Chen CL; Tsai YC; Ting CH; Chien YH; Lee NC; Hwu WL
Hum Mol Genet; 2016 Feb; 25(4):631-41. PubMed ID: 26647309
[TBL] [Abstract][Full Text] [Related]
14. Chronic treatment with lithium does not improve neuromuscular phenotype in a mouse model of severe spinal muscular atrophy.
Dachs E; Piedrafita L; Hereu M; Esquerda JE; Calderó J
Neuroscience; 2013 Oct; 250():417-33. PubMed ID: 23876328
[TBL] [Abstract][Full Text] [Related]
15. Spinal motor neuron loss occurs through a p53-and-p21-independent mechanism in the Smn
Reedich EJ; Kalski M; Armijo N; Cox GA; DiDonato CJ
Exp Neurol; 2021 Mar; 337():113587. PubMed ID: 33382987
[TBL] [Abstract][Full Text] [Related]
16. Intracellular pathways involved in cell survival are deregulated in mouse and human spinal muscular atrophy motoneurons.
Sansa A; de la Fuente S; Comella JX; Garcera A; Soler RM
Neurobiol Dis; 2021 Jul; 155():105366. PubMed ID: 33845129
[TBL] [Abstract][Full Text] [Related]
17. IPLEX administration improves motor neuron survival and ameliorates motor functions in a severe mouse model of spinal muscular atrophy.
Murdocca M; Malgieri A; Luchetti A; Saieva L; Dobrowolny G; de Leonibus E; Filareto A; Quitadamo MC; Novelli G; Musarò A; Sangiuolo F
Mol Med; 2012 Sep; 18(1):1076-85. PubMed ID: 22669476
[TBL] [Abstract][Full Text] [Related]
18. Interaction between alpha-COP and SMN ameliorates disease phenotype in a mouse model of spinal muscular atrophy.
Custer SK; Astroski JW; Li HX; Androphy EJ
Biochem Biophys Res Commun; 2019 Jun; 514(2):530-537. PubMed ID: 31060774
[TBL] [Abstract][Full Text] [Related]
19. A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology.
Bowerman M; Murray LM; Beauvais A; Pinheiro B; Kothary R
Neuromuscul Disord; 2012 Mar; 22(3):263-76. PubMed ID: 22071333
[TBL] [Abstract][Full Text] [Related]
20. The water extract of Liuwei dihuang possesses multi-protective properties on neurons and muscle tissue against deficiency of survival motor neuron protein.
Tseng YT; Jong YJ; Liang WF; Chang FR; Lo YC
Phytomedicine; 2017 Oct; 34():97-105. PubMed ID: 28899515
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]