BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

313 related articles for article (PubMed ID: 30333554)

  • 1. Translational potential of allosteric modulators targeting the cannabinoid CB
    Lu D; Immadi SS; Wu Z; Kendall DA
    Acta Pharmacol Sin; 2019 Mar; 40(3):324-335. PubMed ID: 30333554
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacological selection of cannabinoid receptor effectors: Signalling, allosteric modulation and bias.
    Manning JJ; Green HM; Glass M; Finlay DB
    Neuropharmacology; 2021 Aug; 193():108611. PubMed ID: 34000272
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Real-time characterization of cannabinoid receptor 1 (CB1 ) allosteric modulators reveals novel mechanism of action.
    Cawston EE; Redmond WJ; Breen CM; Grimsey NL; Connor M; Glass M
    Br J Pharmacol; 2013 Oct; 170(4):893-907. PubMed ID: 23937487
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Assessing Allosteric Modulation of CB
    Scott CE; Kendall DA
    Methods Enzymol; 2017; 593():317-342. PubMed ID: 28750809
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and pharmacological profiling of cannabinoid 1 receptor allosteric modulators: Preclinical efficacy of C2-group GAT211 congeners for reducing intraocular pressure.
    Garai S; Schaffer PC; Laprairie RB; Janero DR; Pertwee RG; Straiker A; Thakur GA
    Bioorg Med Chem; 2021 Nov; 50():116421. PubMed ID: 34634617
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Exploring the Ligand Efficacy of Cannabinoid Receptor 1 (CB1) using Molecular Dynamics Simulations.
    Jung SW; Cho AE; Yu W
    Sci Rep; 2018 Sep; 8(1):13787. PubMed ID: 30213978
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor.
    Nguyen T; Li JX; Thomas BF; Wiley JL; Kenakin TP; Zhang Y
    Med Res Rev; 2017 May; 37(3):441-474. PubMed ID: 27879006
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Allosteric modulators targeting cannabinoid cb1 and cb2 receptors: implications for drug discovery.
    Gado F; Meini S; Bertini S; Digiacomo M; Macchia M; Manera C
    Future Med Chem; 2019 Aug; 11(15):2019-2037. PubMed ID: 31517528
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modern approaches to the development of synthetic cannabinoid receptor probes.
    Saldaña-Shumaker SL; Grenning AJ; Cunningham CW
    Pharmacol Biochem Behav; 2021 Apr; 203():173119. PubMed ID: 33508249
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Allosteric modulation of a cannabinoid G protein-coupled receptor: binding site elucidation and relationship to G protein signaling.
    Shore DM; Baillie GL; Hurst DH; Navas F; Seltzman HH; Marcu JP; Abood ME; Ross RA; Reggio PH
    J Biol Chem; 2014 Feb; 289(9):5828-45. PubMed ID: 24366865
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities.
    Khurana L; Mackie K; Piomelli D; Kendall DA
    Neuropharmacology; 2017 Sep; 124():3-12. PubMed ID: 28527758
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthetic Cannabinoid Receptor Agonists and Antagonists: Implication in CNS Disorders.
    Manera C; Arena C; Chicca A
    Recent Pat CNS Drug Discov; 2016; 10(2):142-156. PubMed ID: 27193072
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Allosteric Modulation of Cannabinoid Receptor 1-Current Challenges and Future Opportunities.
    Hryhorowicz S; Kaczmarek-Ryś M; Andrzejewska A; Staszak K; Hryhorowicz M; Korcz A; Słomski R
    Int J Mol Sci; 2019 Nov; 20(23):. PubMed ID: 31771126
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CB
    Mielnik CA; Lam VM; Ross RA
    Prog Neuropsychopharmacol Biol Psychiatry; 2021 Mar; 106():110163. PubMed ID: 33152384
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Endocannabinoids and Their Pharmacological Actions.
    Pertwee RG
    Handb Exp Pharmacol; 2015; 231():1-37. PubMed ID: 26408156
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CB1 Cannabinoid Receptor Signaling and Biased Signaling.
    Leo LM; Abood ME
    Molecules; 2021 Sep; 26(17):. PubMed ID: 34500853
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enantiomer-specific positive allosteric modulation of CB
    Mitjavila J; Yin D; Kulkarni PM; Zanato C; Thakur GA; Ross R; Greig I; Mackie K; Straiker A
    Pharmacol Res; 2018 Mar; 129():475-481. PubMed ID: 29158048
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe.
    Laprairie RB; Kulkarni AR; Kulkarni PM; Hurst DP; Lynch D; Reggio PH; Janero DR; Pertwee RG; Stevenson LA; Kelly ME; Denovan-Wright EM; Thakur GA
    ACS Chem Neurosci; 2016 Jun; 7(6):776-98. PubMed ID: 27046127
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Multiple Binding Sites Contribute to the Mechanism of Mixed Agonistic and Positive Allosteric Modulators of the Cannabinoid CB1 Receptor.
    Saleh N; Hucke O; Kramer G; Schmidt E; Montel F; Lipinski R; Ferger B; Clark T; Hildebrand PW; Tautermann CS
    Angew Chem Int Ed Engl; 2018 Mar; 57(10):2580-2585. PubMed ID: 29314474
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Positive allosteric modulation of the type 1 cannabinoid receptor reduces the signs and symptoms of Huntington's disease in the R6/2 mouse model.
    Laprairie RB; Bagher AM; Rourke JL; Zrein A; Cairns EA; Kelly MEM; Sinal CJ; Kulkarni PM; Thakur GA; Denovan-Wright EM
    Neuropharmacology; 2019 Jun; 151():1-12. PubMed ID: 30940536
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.