184 related articles for article (PubMed ID: 30335983)
1. Structural Basis for Isoform Selective Nitric Oxide Synthase Inhibition by Thiophene-2-carboximidamides.
Li H; Evenson RJ; Chreifi G; Silverman RB; Poulos TL
Biochemistry; 2018 Nov; 57(44):6319-6325. PubMed ID: 30335983
[TBL] [Abstract][Full Text] [Related]
2. Structural basis for isoform-selective inhibition in nitric oxide synthase.
Poulos TL; Li H
Acc Chem Res; 2013 Feb; 46(2):390-8. PubMed ID: 23030042
[TBL] [Abstract][Full Text] [Related]
3. Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Flinspach ML; Li H; Jamal J; Yang W; Huang H; Hah JM; Gómez-Vidal JA; Litzinger EA; Silverman RB; Poulos TL
Nat Struct Mol Biol; 2004 Jan; 11(1):54-9. PubMed ID: 14718923
[TBL] [Abstract][Full Text] [Related]
4. Recent advances toward improving the bioavailability of neuronal nitric oxide synthase inhibitors.
Huang H; Silverman RB
Curr Top Med Chem; 2013; 13(7):803-12. PubMed ID: 23578024
[TBL] [Abstract][Full Text] [Related]
5. Design of selective neuronal nitric oxide synthase inhibitors for the prevention and treatment of neurodegenerative diseases.
Silverman RB
Acc Chem Res; 2009 Mar; 42(3):439-51. PubMed ID: 19154146
[TBL] [Abstract][Full Text] [Related]
6. Potent and selective double-headed thiophene-2-carboximidamide inhibitors of neuronal nitric oxide synthase for the treatment of melanoma.
Huang H; Li H; Yang S; Chreifi G; Martásek P; Roman LJ; Meyskens FL; Poulos TL; Silverman RB
J Med Chem; 2014 Feb; 57(3):686-700. PubMed ID: 24447275
[TBL] [Abstract][Full Text] [Related]
7. Insights into the structural determinants for selective inhibition of nitric oxide synthase isoforms.
Oliveira BL; Moreira IS; Fernandes PA; Ramos MJ; Santos I; Correia JD
J Mol Model; 2013 Apr; 19(4):1537-51. PubMed ID: 23263357
[TBL] [Abstract][Full Text] [Related]
8. Crystallographic and Computational Insights into Isoform-Selective Dynamics in Nitric Oxide Synthase.
Li H; Hardy CD; Reidl CT; Jing Q; Xue F; Cinelli M; Silverman RB; Poulos TL
Biochemistry; 2024 Mar; 63(6):788-796. PubMed ID: 38417024
[TBL] [Abstract][Full Text] [Related]
9. Screening of novel and selective inhibitors for neuronal nitric oxide synthase (nNOS) via structure-based drug design techniques.
Boumezber S; Yelekçi K
J Biomol Struct Dyn; 2023 May; 41(8):3607-3629. PubMed ID: 35322764
[TBL] [Abstract][Full Text] [Related]
10. Structures of human constitutive nitric oxide synthases.
Li H; Jamal J; Plaza C; Pineda SH; Chreifi G; Jing Q; Cinelli MA; Silverman RB; Poulos TL
Acta Crystallogr D Biol Crystallogr; 2014 Oct; 70(Pt 10):2667-74. PubMed ID: 25286850
[TBL] [Abstract][Full Text] [Related]
11. Electrostatic Control of Isoform Selective Inhibitor Binding in Nitric Oxide Synthase.
Li H; Wang HY; Kang S; Silverman RB; Poulos TL
Biochemistry; 2016 Jul; 55(26):3702-7. PubMed ID: 27250740
[TBL] [Abstract][Full Text] [Related]
12. Exploring the binding conformations of bulkier dipeptide amide inhibitors in constitutive nitric oxide synthases.
Li H; Flinspach ML; Igarashi J; Jamal J; Yang W; Gómez-Vidal JA; Litzinger EA; Huang H; Erdal EP; Silverman RB; Poulos TL
Biochemistry; 2005 Nov; 44(46):15222-9. PubMed ID: 16285725
[TBL] [Abstract][Full Text] [Related]
13. Peripheral but crucial: a hydrophobic pocket (Tyr(706), Leu(337), and Met(336)) for potent and selective inhibition of neuronal nitric oxide synthase.
Xue F; Li H; Fang J; Roman LJ; Martásek P; Poulos TL; Silverman RB
Bioorg Med Chem Lett; 2010 Nov; 20(21):6258-61. PubMed ID: 20833542
[TBL] [Abstract][Full Text] [Related]
14. Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model.
Delker SL; Ji H; Li H; Jamal J; Fang J; Xue F; Silverman RB; Poulos TL
J Am Chem Soc; 2010 Apr; 132(15):5437-42. PubMed ID: 20337441
[TBL] [Abstract][Full Text] [Related]
15. Role of zinc in isoform-selective inhibitor binding to neuronal nitric oxide synthase .
Delker SL; Xue F; Li H; Jamal J; Silverman RB; Poulos TL
Biochemistry; 2010 Dec; 49(51):10803-10. PubMed ID: 21138269
[TBL] [Abstract][Full Text] [Related]
16. Structure-guided design of selective inhibitors of neuronal nitric oxide synthase.
Huang H; Li H; Martásek P; Roman LJ; Poulos TL; Silverman RB
J Med Chem; 2013 Apr; 56(7):3024-32. PubMed ID: 23451760
[TBL] [Abstract][Full Text] [Related]
17. Hydroxyethylene isosteres of selective neuronal nitric oxide synthase inhibitors.
Erdal EP; Martásek P; Roman LJ; Silverman RB
Bioorg Med Chem; 2007 Sep; 15(18):6096-108. PubMed ID: 17614291
[TBL] [Abstract][Full Text] [Related]
18. First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate.
Cinelli MA; Reidl CT; Li H; Chreifi G; Poulos TL; Silverman RB
J Med Chem; 2020 May; 63(9):4528-4554. PubMed ID: 32302123
[TBL] [Abstract][Full Text] [Related]
19. Nitric oxide synthase inhibitors that interact with both heme propionate and tetrahydrobiopterin show high isoform selectivity.
Kang S; Tang W; Li H; Chreifi G; Martásek P; Roman LJ; Poulos TL; Silverman RB
J Med Chem; 2014 May; 57(10):4382-96. PubMed ID: 24758147
[TBL] [Abstract][Full Text] [Related]
20. Crystal structures of constitutive nitric oxide synthases in complex with de novo designed inhibitors.
Igarashi J; Li H; Jamal J; Ji H; Fang J; Lawton GR; Silverman RB; Poulos TL
J Med Chem; 2009 Apr; 52(7):2060-6. PubMed ID: 19296678
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]