392 related articles for article (PubMed ID: 30336023)
21. The Lipophilic Purine Nucleoside-Tdp1 Inhibitor-Enhances DNA Damage Induced by Topotecan In Vitro and Potentiates the Antitumor Effect of Topotecan In Vivo.
Chernyshova IA; Zakharenko AL; Kurochkin NN; Dyrkheeva NS; Kornienko TE; Popova NA; Nikolin VP; Ilina ES; Zharkov TD; Kupryushkin MS; Oslovsky VE; Drenichev MS; Lavrik OI
Molecules; 2022 Dec; 28(1):. PubMed ID: 36615517
[TBL] [Abstract][Full Text] [Related]
22. Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment.
Beretta GL; Cossa G; Gatti L; Zunino F; Perego P
Curr Med Chem; 2010; 17(15):1500-8. PubMed ID: 20166932
[TBL] [Abstract][Full Text] [Related]
23. 4-Pregnen-21-ol-3,20-dione-21-(4-bromobenzenesulfonate) (NSC 88915) and related novel steroid derivatives as tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors.
Dexheimer TS; Gediya LK; Stephen AG; Weidlich I; Antony S; Marchand C; Interthal H; Nicklaus M; Fisher RJ; Njar VC; Pommier Y
J Med Chem; 2009 Nov; 52(22):7122-31. PubMed ID: 19883083
[TBL] [Abstract][Full Text] [Related]
24. Topoisomerase I activity and sensitivity to camptothecin in breast cancer-derived cells: a comparative study.
Tesauro C; Simonsen AK; Andersen MB; Petersen KW; Kristoffersen EL; Algreen L; Hansen NY; Andersen AB; Jakobsen AK; Stougaard M; Gromov P; Knudsen BR; Gromova I
BMC Cancer; 2019 Nov; 19(1):1158. PubMed ID: 31783818
[TBL] [Abstract][Full Text] [Related]
25. Synthesis, anti-cancer screening and tyrosyl-DNA phosphodiesterase 1 (Tdp1) inhibition activity of novel piperidinyl sulfamides.
Jun JH; Kumar V; Dexheimer TS; Wedlich I; Nicklaus MC; Pommier Y; Malhotra SV
Eur J Pharm Sci; 2018 Jan; 111():337-348. PubMed ID: 29037996
[TBL] [Abstract][Full Text] [Related]
26. Synthesis and biological evaluation of 5-aminoethyl benzophenanthridone derivatives as DNA topoisomerase IB inhibitors.
Tang WL; Zhang Y; Hu DX; Yang H; Yu Q; Chen JW; Agama K; Pommier Y; An LK
Eur J Med Chem; 2019 Sep; 178():81-92. PubMed ID: 31176097
[TBL] [Abstract][Full Text] [Related]
27. TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.
Zeng Z; Sharma A; Ju L; Murai J; Umans L; Vermeire L; Pommier Y; Takeda S; Huylebroeck D; Caldecott KW; El-Khamisy SF
Nucleic Acids Res; 2012 Sep; 40(17):8371-80. PubMed ID: 22740648
[TBL] [Abstract][Full Text] [Related]
28. Correlation between topoisomerase I and tyrosyl-DNA phosphodiesterase 1 activities in non-small cell lung cancer tissue.
Jakobsen AK; Lauridsen KL; Samuel EB; Proszek J; Knudsen BR; Hager H; Stougaard M
Exp Mol Pathol; 2015 Aug; 99(1):56-64. PubMed ID: 25987486
[TBL] [Abstract][Full Text] [Related]
29. Design and Synthesis of Chlorinated and Fluorinated 7-Azaindenoisoquinolines as Potent Cytotoxic Anticancer Agents That Inhibit Topoisomerase I.
Elsayed MSA; Su Y; Wang P; Sethi T; Agama K; Ravji A; Redon CE; Kiselev E; Horzmann KA; Freeman JL; Pommier Y; Cushman M
J Med Chem; 2017 Jul; 60(13):5364-5376. PubMed ID: 28657311
[TBL] [Abstract][Full Text] [Related]
30. Synthesis and biological evaluation of novel tyrosyl-DNA phosphodiesterase 1 inhibitors with a benzopentathiepine moiety.
Zakharenko A; Khomenko T; Zhukova S; Koval O; Zakharova O; Anarbaev R; Lebedeva N; Korchagina D; Komarova N; Vasiliev V; Reynisson J; Volcho K; Salakhutdinov N; Lavrik O
Bioorg Med Chem; 2015 May; 23(9):2044-52. PubMed ID: 25819333
[TBL] [Abstract][Full Text] [Related]
31. The First Berberine-Based Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), an Important DNA Repair Enzyme.
Gladkova ED; Nechepurenko IV; Bredikhin RA; Chepanova AA; Zakharenko AL; Luzina OA; Ilina ES; Dyrkheeva NS; Mamontova EM; Anarbaev RO; Reynisson J; Volcho KP; Salakhutdinov NF; Lavrik OI
Int J Mol Sci; 2020 Sep; 21(19):. PubMed ID: 32998385
[TBL] [Abstract][Full Text] [Related]
32. Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy.
Khomenko TM; Zakharenko AL; Chepanova AA; Ilina ES; Zakharova OD; Kaledin VI; Nikolin VP; Popova NA; Korchagina DV; Reynisson J; Chand R; Ayine-Tora DM; Patel J; Leung IKH; Volcho KP; Salakhutdinov NF; Lavrik OI
Int J Mol Sci; 2019 Dec; 21(1):. PubMed ID: 31878088
[TBL] [Abstract][Full Text] [Related]
33. Synthesis, cytotoxicity and structure-activity relationship of indolizinoquinolinedione derivatives as DNA topoisomerase IB catalytic inhibitors.
Yu Q; Yang H; Zhu TW; Yu LM; Chen JW; Gu LQ; Huang ZS; An LK
Eur J Med Chem; 2018 May; 152():195-207. PubMed ID: 29705710
[TBL] [Abstract][Full Text] [Related]
34. New strategies in the discovery of novel non-camptothecin topoisomerase I inhibitors.
Sheng C; Miao Z; Zhang W
Curr Med Chem; 2011; 18(28):4389-409. PubMed ID: 21861816
[TBL] [Abstract][Full Text] [Related]
35. Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models.
Zakharenko AL; Luzina OA; Sokolov DN; Kaledin VI; Nikolin VP; Popova NA; Patel J; Zakharova OD; Chepanova AA; Zafar A; Reynisson J; Leung E; Leung IKH; Volcho KP; Salakhutdinov NF; Lavrik OI
Eur J Med Chem; 2019 Jan; 161():581-593. PubMed ID: 30396105
[TBL] [Abstract][Full Text] [Related]
36. TDP1-independent pathways in the process and repair of TOP1-induced DNA damage.
Zhang H; Xiong Y; Su D; Wang C; Srivastava M; Tang M; Feng X; Huang M; Chen Z; Chen J
Nat Commun; 2022 Jul; 13(1):4240. PubMed ID: 35869071
[TBL] [Abstract][Full Text] [Related]
37. A Novel Class of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Contains the Octahydro-2
Li-Zhulanov NS; Zakharenko AL; Chepanova AA; Patel J; Zafar A; Volcho KP; Salakhutdinov NF; Reynisson J; Leung IKH; Lavrik OI
Molecules; 2018 Sep; 23(10):. PubMed ID: 30261631
[TBL] [Abstract][Full Text] [Related]
38. New Deoxycholic Acid Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitors Also Inhibit Tyrosyl-DNA Phosphodiesterase 2.
Salomatina OV; Dyrkheeva NS; Popadyuk II; Zakharenko AL; Ilina ES; Komarova NI; Reynisson J; Salakhutdinov NF; Lavrik OI; Volcho KP
Molecules; 2021 Dec; 27(1):. PubMed ID: 35011303
[TBL] [Abstract][Full Text] [Related]
39. PARP1-TDP1 coupling for the repair of topoisomerase I-induced DNA damage.
Das BB; Huang SY; Murai J; Rehman I; Amé JC; Sengupta S; Das SK; Majumdar P; Zhang H; Biard D; Majumder HK; Schreiber V; Pommier Y
Nucleic Acids Res; 2014 Apr; 42(7):4435-49. PubMed ID: 24493735
[TBL] [Abstract][Full Text] [Related]
40. Repair of topoisomerase 1-induced DNA damage by tyrosyl-DNA phosphodiesterase 2 (TDP2) is dependent on its magnesium binding.
Shimizu N; Hamada Y; Morozumi R; Yamamoto J; Iwai S; Sugiyama KI; Ide H; Tsuda M
J Biol Chem; 2023 Aug; 299(8):104988. PubMed ID: 37392847
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
