645 related articles for article (PubMed ID: 30340601)
1. Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.
Ma Q; Zhao Z; Sagare AP; Wu Y; Wang M; Owens NC; Verghese PB; Herz J; Holtzman DM; Zlokovic BV
Mol Neurodegener; 2018 Oct; 13(1):57. PubMed ID: 30340601
[TBL] [Abstract][Full Text] [Related]
2. Apolipoprotein E isoform-specific effects on lipoprotein receptor processing.
Bachmeier C; Shackleton B; Ojo J; Paris D; Mullan M; Crawford F
Neuromolecular Med; 2014 Dec; 16(4):686-96. PubMed ID: 25015123
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.
Shackleton B; Crawford F; Bachmeier C
Fluids Barriers CNS; 2016 Aug; 13(1):14. PubMed ID: 27503326
[TBL] [Abstract][Full Text] [Related]
4. apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain.
Deane R; Sagare A; Hamm K; Parisi M; Lane S; Finn MB; Holtzman DM; Zlokovic BV
J Clin Invest; 2008 Dec; 118(12):4002-13. PubMed ID: 19033669
[TBL] [Abstract][Full Text] [Related]
5. Differences in amyloid-β clearance across mouse and human blood-brain barrier models: kinetic analysis and mechanistic modeling.
Qosa H; Abuasal BS; Romero IA; Weksler B; Couraud PO; Keller JN; Kaddoumi A
Neuropharmacology; 2014 Apr; 79():668-78. PubMed ID: 24467845
[TBL] [Abstract][Full Text] [Related]
6. Amyloid-β protein modulates the perivascular clearance of neuronal apolipoprotein E in mouse models of Alzheimer's disease.
Rolyan H; Feike AC; Upadhaya AR; Waha A; Van Dooren T; Haass C; Birkenmeier G; Pietrzik CU; Van Leuven F; Thal DR
J Neural Transm (Vienna); 2011 May; 118(5):699-712. PubMed ID: 21210284
[TBL] [Abstract][Full Text] [Related]
7. APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
Tachibana M; Holm ML; Liu CC; Shinohara M; Aikawa T; Oue H; Yamazaki Y; Martens YA; Murray ME; Sullivan PM; Weyer K; Glerup S; Dickson DW; Bu G; Kanekiyo T
J Clin Invest; 2019 Mar; 129(3):1272-1277. PubMed ID: 30741718
[TBL] [Abstract][Full Text] [Related]
8. 1,25-Dihydroxyvitamin D3 regulates expression of LRP1 and RAGE in vitro and in vivo, enhancing Aβ1-40 brain-to-blood efflux and peripheral uptake transport.
Guo YX; He LY; Zhang M; Wang F; Liu F; Peng WX
Neuroscience; 2016 May; 322():28-38. PubMed ID: 26820600
[TBL] [Abstract][Full Text] [Related]
9. Apolipoprotein E increases cell association of amyloid-β 40 through heparan sulfate and LRP1 dependent pathways.
O'Callaghan P; Noborn F; Sehlin D; Li JP; Lannfelt L; Lindahl U; Zhang X
Amyloid; 2014 Jun; 21(2):76-87. PubMed ID: 24491019
[TBL] [Abstract][Full Text] [Related]
10. The role of LRP1 in Aβ efflux transport across the blood-brain barrier and cognitive dysfunction in diabetes mellitus.
P X; Zz L; Gg J; Lp W; Cm B; Yl W; Chen MF; W L
Neurochem Int; 2022 Nov; 160():105417. PubMed ID: 36067928
[TBL] [Abstract][Full Text] [Related]
11. Apolipoprotein E regulates the integrity of tight junctions in an isoform-dependent manner in an in vitro blood-brain barrier model.
Nishitsuji K; Hosono T; Nakamura T; Bu G; Michikawa M
J Biol Chem; 2011 May; 286(20):17536-42. PubMed ID: 21471207
[TBL] [Abstract][Full Text] [Related]
12. Apolipoprotein E/Amyloid-β Complex Accumulates in Alzheimer Disease Cortical Synapses via Apolipoprotein E Receptors and Is Enhanced by APOE4.
Bilousova T; Melnik M; Miyoshi E; Gonzalez BL; Poon WW; Vinters HV; Miller CA; Corrada MM; Kawas C; Hatami A; Albay R; Glabe C; Gylys KH
Am J Pathol; 2019 Aug; 189(8):1621-1636. PubMed ID: 31108099
[TBL] [Abstract][Full Text] [Related]
13. The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM.
Storck SE; Hartz AMS; Bernard J; Wolf A; Kachlmeier A; Mahringer A; Weggen S; Pahnke J; Pietrzik CU
Brain Behav Immun; 2018 Oct; 73():21-33. PubMed ID: 30041013
[TBL] [Abstract][Full Text] [Related]
14. LRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β.
Kanekiyo T; Liu CC; Shinohara M; Li J; Bu G
J Neurosci; 2012 Nov; 32(46):16458-65. PubMed ID: 23152628
[TBL] [Abstract][Full Text] [Related]
15. Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition.
Liu CC; Hu J; Zhao N; Wang J; Wang N; Cirrito JR; Kanekiyo T; Holtzman DM; Bu G
J Neurosci; 2017 Apr; 37(15):4023-4031. PubMed ID: 28275161
[TBL] [Abstract][Full Text] [Related]
16. Pericyte implantation in the brain enhances cerebral blood flow and reduces amyloid-β pathology in amyloid model mice.
Tachibana M; Yamazaki Y; Liu CC; Bu G; Kanekiyo T
Exp Neurol; 2018 Feb; 300():13-21. PubMed ID: 29106980
[TBL] [Abstract][Full Text] [Related]
17. Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system.
Bell RD; Sagare AP; Friedman AE; Bedi GS; Holtzman DM; Deane R; Zlokovic BV
J Cereb Blood Flow Metab; 2007 May; 27(5):909-18. PubMed ID: 17077814
[TBL] [Abstract][Full Text] [Related]
18. Functional role of lipoprotein receptors in Alzheimer's disease.
Jaeger S; Pietrzik CU
Curr Alzheimer Res; 2008 Feb; 5(1):15-25. PubMed ID: 18288927
[TBL] [Abstract][Full Text] [Related]
19. In vitro discrimination of the role of LRP1 at the BBB cellular level: focus on brain capillary endothelial cells and brain pericytes.
Candela P; Saint-Pol J; Kuntz M; Boucau MC; Lamartiniere Y; Gosselet F; Fenart L
Brain Res; 2015 Jan; 1594():15-26. PubMed ID: 25451130
[TBL] [Abstract][Full Text] [Related]
20. Amylin Enhances Amyloid-β Peptide Brain to Blood Efflux Across the Blood-Brain Barrier.
Mohamed LA; Zhu H; Mousa YM; Wang E; Qiu WQ; Kaddoumi A
J Alzheimers Dis; 2017; 56(3):1087-1099. PubMed ID: 28059785
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
