BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 30349052)

  • 1. APP promotes osteoblast survival and bone formation by regulating mitochondrial function and preventing oxidative stress.
    Pan JX; Tang F; Xiong F; Xiong L; Zeng P; Wang B; Zhao K; Guo H; Shun C; Xia WF; Mei L; Xiong WC
    Cell Death Dis; 2018 Oct; 9(11):1077. PubMed ID: 30349052
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Swedish mutant APP suppresses osteoblast differentiation and causes osteoporotic deficit, which are ameliorated by N-acetyl-L-cysteine.
    Xia WF; Jung JU; Shun C; Xiong S; Xiong L; Shi XM; Mei L; Xiong WC
    J Bone Miner Res; 2013 Oct; 28(10):2122-35. PubMed ID: 23649480
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The mitochondria-targeted small molecule SS31 delays progression of behavioral deficits by attenuating β-amyloid plaque formation and mitochondrial/synaptic deterioration in APP/PS1 mice.
    Jia YL; Wang W; Han N; Sun HL; Dong FM; Song YX; Feng RF; Wang JH
    Biochem Biophys Res Commun; 2023 May; 658():36-43. PubMed ID: 37018887
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Iron Chelation Inhibits Osteoclastic Differentiation In Vitro and in Tg2576 Mouse Model of Alzheimer's Disease.
    Guo JP; Pan JX; Xiong L; Xia WF; Cui S; Xiong WC
    PLoS One; 2015; 10(11):e0139395. PubMed ID: 26575486
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ligustilide-loaded liposome ameliorates mitochondrial impairments and improves cognitive function via the PKA/AKAP1 signaling pathway in a mouse model of Alzheimer's disease.
    Zhang Q; Zhang X; Yang B; Li Y; Sun XH; Li X; Sui P; Wang YB; Tian SY; Wang CY
    CNS Neurosci Ther; 2024 Mar; 30(3):e14460. PubMed ID: 37718506
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Aging-related increase in oxidative stress correlates with developmental pattern of beta-secretase activity and beta-amyloid plaque formation in transgenic Tg2576 mice with Alzheimer-like pathology.
    Apelt J; Bigl M; Wunderlich P; Schliebs R
    Int J Dev Neurosci; 2004 Nov; 22(7):475-84. PubMed ID: 15465277
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amyloid-β plaque formation and reactive gliosis are required for induction of cognitive deficits in App knock-in mouse models of Alzheimer's disease.
    Sakakibara Y; Sekiya M; Saito T; Saido TC; Iijima KM
    BMC Neurosci; 2019 Mar; 20(1):13. PubMed ID: 30894120
    [TBL] [Abstract][Full Text] [Related]  

  • 8. APP/PS1 mice overexpressing SREBP-2 exhibit combined Aβ accumulation and tau pathology underlying Alzheimer's disease.
    Barbero-Camps E; Fernández A; Martínez L; Fernández-Checa JC; Colell A
    Hum Mol Genet; 2013 Sep; 22(17):3460-76. PubMed ID: 23648430
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice.
    Aliev G; Seyidova D; Lamb BT; Obrenovich ME; Siedlak SL; Vinters HV; Friedland RP; LaManna JC; Smith MA; Perry G
    Neurol Res; 2003 Sep; 25(6):665-74. PubMed ID: 14503022
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression.
    Manczak M; Anekonda TS; Henson E; Park BS; Quinn J; Reddy PH
    Hum Mol Genet; 2006 May; 15(9):1437-49. PubMed ID: 16551656
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A neuronal model of Alzheimer's disease: an insight into the mechanisms of oxidative stress-mediated mitochondrial injury.
    Sompol P; Ittarat W; Tangpong J; Chen Y; Doubinskaia I; Batinic-Haberle I; Abdul HM; Butterfield DA; St Clair DK
    Neuroscience; 2008 Apr; 153(1):120-30. PubMed ID: 18353561
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Potential in vivo amelioration by N-acetyl-L-cysteine of oxidative stress in brain in human double mutant APP/PS-1 knock-in mice: toward therapeutic modulation of mild cognitive impairment.
    Huang Q; Aluise CD; Joshi G; Sultana R; St Clair DK; Markesbery WR; Butterfield DA
    J Neurosci Res; 2010 Sep; 88(12):2618-29. PubMed ID: 20648652
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease.
    Dutescu RM; Li QX; Crowston J; Masters CL; Baird PN; Culvenor JG
    Graefes Arch Clin Exp Ophthalmol; 2009 Sep; 247(9):1213-21. PubMed ID: 19271231
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitochondrial vulnerability to oxidation in human brain organoids modelling Alzheimer's disease.
    Holubiec MI; Alloatti M; Bianchelli J; Greloni F; Arnaiz C; Gonzalez Prinz M; Fernandez Bessone I; Pozo Devoto V; Falzone TL
    Free Radic Biol Med; 2023 Nov; 208():394-401. PubMed ID: 37657763
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An early dysregulation of FAK and MEK/ERK signaling pathways precedes the β-amyloid deposition in the olfactory bulb of APP/PS1 mouse model of Alzheimer's disease.
    Lachén-Montes M; González-Morales A; de Morentin XM; Pérez-Valderrama E; Ausín K; Zelaya MV; Serna A; Aso E; Ferrer I; Fernández-Irigoyen J; Santamaría E
    J Proteomics; 2016 Oct; 148():149-58. PubMed ID: 27498392
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate.
    Dixit S; Fessel JP; Harrison FE
    Free Radic Biol Med; 2017 Nov; 112():515-523. PubMed ID: 28863942
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Geniposide attenuates mitochondrial dysfunction and memory deficits in APP/PS1 transgenic mice.
    Lv C; Liu X; Liu H; Chen T; Zhang W
    Curr Alzheimer Res; 2014; 11(6):580-7. PubMed ID: 25034042
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Osteoblastic Swedish mutant APP expedites brain deficits by inducing endoplasmic reticulum stress-driven senescence.
    Pan JX; Sun D; Lee D; Xiong L; Ren X; Guo HH; Yao LL; Lu Y; Jung C; Xiong WC
    Commun Biol; 2021 Nov; 4(1):1326. PubMed ID: 34824365
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease.
    Manczak M; Reddy PH
    Hum Mol Genet; 2012 Dec; 21(23):5131-46. PubMed ID: 22926141
    [TBL] [Abstract][Full Text] [Related]  

  • 20. APPswe/Aβ regulation of osteoclast activation and RAGE expression in an age-dependent manner.
    Cui S; Xiong F; Hong Y; Jung JU; Li XS; Liu JZ; Yan R; Mei L; Feng X; Xiong WC
    J Bone Miner Res; 2011 May; 26(5):1084-98. PubMed ID: 21542009
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.