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2. DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis. Enriquez-Rios V; Dumitrache LC; Downing SM; Li Y; Brown EJ; Russell HR; McKinnon PJ J Neurosci; 2017 Jan; 37(4):893-905. PubMed ID: 28123024 [TBL] [Abstract][Full Text] [Related]
3. ATR-dependent phosphorylation of DNA-dependent protein kinase catalytic subunit in response to UV-induced replication stress. Yajima H; Lee KJ; Chen BP Mol Cell Biol; 2006 Oct; 26(20):7520-8. PubMed ID: 16908529 [TBL] [Abstract][Full Text] [Related]
4. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Falck J; Coates J; Jackson SP Nature; 2005 Mar; 434(7033):605-11. PubMed ID: 15758953 [TBL] [Abstract][Full Text] [Related]
5. A synthetic lethal screen reveals enhanced sensitivity to ATR inhibitor treatment in mantle cell lymphoma with ATM loss-of-function. Menezes DL; Holt J; Tang Y; Feng J; Barsanti P; Pan Y; Ghoddusi M; Zhang W; Thomas G; Holash J; Lees E; Taricani L Mol Cancer Res; 2015 Jan; 13(1):120-9. PubMed ID: 25232030 [TBL] [Abstract][Full Text] [Related]
6. Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition. Middleton FK; Patterson MJ; Elstob CJ; Fordham S; Herriott A; Wade MA; McCormick A; Edmondson R; May FE; Allan JM; Pollard JR; Curtin NJ Oncotarget; 2015 Oct; 6(32):32396-409. PubMed ID: 26486089 [TBL] [Abstract][Full Text] [Related]
7. Synthetic Lethality through the Lens of Medicinal Chemistry. Myers SH; Ortega JA; Cavalli A J Med Chem; 2020 Dec; 63(23):14151-14183. PubMed ID: 33135887 [TBL] [Abstract][Full Text] [Related]
8. Therapeutic targeting of a robust non-oncogene addiction to PRKDC in ATM-defective tumors. Riabinska A; Daheim M; Herter-Sprie GS; Winkler J; Fritz C; Hallek M; Thomas RK; Kreuzer KA; Frenzel LP; Monfared P; Martins-Boucas J; Chen S; Reinhardt HC Sci Transl Med; 2013 Jun; 5(189):189ra78. PubMed ID: 23761041 [TBL] [Abstract][Full Text] [Related]
9. The ATM and Rad3-Related (ATR) Protein Kinase Pathway Is Activated by Herpes Simplex Virus 1 and Required for Efficient Viral Replication. Edwards TG; Bloom DC; Fisher C J Virol; 2018 Mar; 92(6):. PubMed ID: 29263259 [TBL] [Abstract][Full Text] [Related]
10. Targeting the replication stress response through synthetic lethal strategies in cancer medicine. Ngoi NYL; Pham MM; Tan DSP; Yap TA Trends Cancer; 2021 Oct; 7(10):930-957. PubMed ID: 34215565 [TBL] [Abstract][Full Text] [Related]
11. Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase. Wang H; Guan J; Wang H; Perrault AR; Wang Y; Iliakis G Cancer Res; 2001 Dec; 61(23):8554-63. PubMed ID: 11731442 [TBL] [Abstract][Full Text] [Related]
12. Targeting DNA repair mechanisms in cancer. Furgason JM; Bahassi el M Pharmacol Ther; 2013 Mar; 137(3):298-308. PubMed ID: 23107892 [TBL] [Abstract][Full Text] [Related]
13. Targeting ATR as Cancer Therapy: A new era for synthetic lethality and synergistic combinations? Bradbury A; Hall S; Curtin N; Drew Y Pharmacol Ther; 2020 Mar; 207():107450. PubMed ID: 31836456 [TBL] [Abstract][Full Text] [Related]
14. Both ATM and DNA-PK Are the Main Regulators of HIV-1 Post-Integrational DNA Repair. Anisenko A; Nefedova A; Agapkina Y; Gottikh M Int J Mol Sci; 2023 Feb; 24(3):. PubMed ID: 36769109 [TBL] [Abstract][Full Text] [Related]
15. The development of ataxia telangiectasia mutated kinase inhibitors. Andrs M; Korabecny J; Nepovimova E; Jun D; Hodny Z; Moravcova S; Hanzlikova H; Kuca K Mini Rev Med Chem; 2014; 14(10):805-11. PubMed ID: 25138084 [TBL] [Abstract][Full Text] [Related]
16. DNA-activated protein kinase functions in a newly observed S phase checkpoint that links histone mRNA abundance with DNA replication. Müller B; Blackburn J; Feijoo C; Zhao X; Smythe C J Cell Biol; 2007 Dec; 179(7):1385-98. PubMed ID: 18158334 [TBL] [Abstract][Full Text] [Related]
17. Inactivation of PRIM1 Function Sensitizes Cancer Cells to ATR and CHK1 Inhibitors. Job A; Schmitt LM; von Wenserski L; Lankat-Buttgereit B; Gress TM; Buchholz M; Gallmeier E Neoplasia; 2018 Nov; 20(11):1135-1143. PubMed ID: 30257222 [TBL] [Abstract][Full Text] [Related]
18. [Potentials of DNA-PKcs, Ku80, and ATM in enhancing radiosensitivity of cervical carcinoma cells]. Zhuang L; Yu SY; Huang XY; Cao Y; Xiong HH Ai Zheng; 2007 Jul; 26(7):724-9. PubMed ID: 17626748 [TBL] [Abstract][Full Text] [Related]
19. ATM and ATR as therapeutic targets in cancer. Weber AM; Ryan AJ Pharmacol Ther; 2015 May; 149():124-38. PubMed ID: 25512053 [TBL] [Abstract][Full Text] [Related]
20. DNA damage sensors ATM, ATR, DNA-PKcs, and PARP-1 are dispensable for human immunodeficiency virus type 1 integration. Ariumi Y; Turelli P; Masutani M; Trono D J Virol; 2005 Mar; 79(5):2973-8. PubMed ID: 15709017 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]