BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 30361237)

  • 1. Evidence for the Validity of Pyridoxic Acid (PDA) as a Plasma-Based Endogenous Probe for OAT1 and OAT3 Function in Healthy Subjects.
    Shen H; Holenarsipur VK; Mariappan TT; Drexler DM; Cantone JL; Rajanna P; Singh Gautam S; Zhang Y; Gan J; Shipkova PA; Marathe P; Humphreys WG
    J Pharmacol Exp Ther; 2019 Jan; 368(1):136-145. PubMed ID: 30361237
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys.
    Shen H; Nelson DM; Oliveira RV; Zhang Y; Mcnaney CA; Gu X; Chen W; Su C; Reily MD; Shipkova PA; Gan J; Lai Y; Marathe P; Humphreys WG
    Drug Metab Dispos; 2018 Feb; 46(2):178-188. PubMed ID: 29162614
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of Elimination Pathways and the Feasibility of Endogenous Metabolites as Biomarkers of Organic Anion Transporter 1/3 Inhibition in Cynomolgus Monkeys.
    Liu R; Hao J; Zhao X; Lai Y
    Drug Metab Dispos; 2023 Jul; 51(7):844-850. PubMed ID: 37059471
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Population pharmacokinetic modeling and simulation to support qualification of pyridoxic acid as endogenous biomarker of OAT1/3 renal transporters.
    Ahmad A; Ogungbenro K; Kunze A; Jacobs F; Snoeys J; Rostami-Hodjegan A; Galetin A
    CPT Pharmacometrics Syst Pharmacol; 2021 May; 10(5):467-477. PubMed ID: 33704919
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Detection of Weak Organic Anion-Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans.
    Zhang Y; Holenarsipur VK; Kandoussi H; Zeng J; Mariappan TT; Sinz M; Shen H
    Drug Metab Dispos; 2020 Oct; 48(10):841-848. PubMed ID: 32723847
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Clinical Investigation on Endogenous Biomarkers to Predict Strong OAT-Mediated Drug-Drug Interactions.
    Willemin ME; Van Der Made TK; Pijpers I; Dillen L; Kunze A; Jonkers S; Steemans K; Tuytelaars A; Jacobs F; Monshouwer M; Scotcher D; Rostami-Hodjegan A; Galetin A; Snoeys J
    Clin Pharmacokinet; 2021 Sep; 60(9):1187-1199. PubMed ID: 33840062
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endogenous Plasma Kynurenic Acid in Human: A Newly Discovered Biomarker for Drug-Drug Interactions Involving Organic Anion Transporter 1 and 3 Inhibition.
    Tang J; Shen H; Zhao X; Holenarsipur VK; Mariappan TT; Zhang Y; Panfen E; Zheng J; Humphreys WG; Lai Y
    Drug Metab Dispos; 2021 Dec; 49(12):1063-1069. PubMed ID: 34599018
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of 4-Pyridoxic Acid PBPK Model to Support Biomarker-Informed Evaluation of OAT1/3 Inhibition and Effect of Chronic Kidney Disease.
    Tan SPF; Willemin ME; Snoeys J; Shen H; Rostami-Hodjegan A; Scotcher D; Galetin A
    Clin Pharmacol Ther; 2023 Dec; 114(6):1243-1253. PubMed ID: 37620246
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of probenecid on blood levels and renal elimination of furosemide and endogenous compounds in rats: Discovery of putative organic anion transporter biomarkers.
    Thakur A; Saradhi Mettu V; Singh DK; Prasad B
    Biochem Pharmacol; 2023 Dec; 218():115867. PubMed ID: 37866801
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibitory effects of p-aminohippurate and probenecid on the renal clearance of adefovir and benzylpenicillin as probe drugs for organic anion transporter (OAT) 1 and OAT3 in humans.
    Maeda K; Tian Y; Fujita T; Ikeda Y; Kumagai Y; Kondo T; Tanabe K; Nakayama H; Horita S; Kusuhara H; Sugiyama Y
    Eur J Pharm Sci; 2014 Aug; 59():94-103. PubMed ID: 24747579
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Investigation of Endogenous Compounds Applicable to Drug-Drug Interaction Studies Involving the Renal Organic Anion Transporters, OAT1 and OAT3, in Humans.
    Tsuruya Y; Kato K; Sano Y; Imamura Y; Maeda K; Kumagai Y; Sugiyama Y; Kusuhara H
    Drug Metab Dispos; 2016 Dec; 44(12):1925-1933. PubMed ID: 27638508
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel hydrophilic interaction chromatography assay characterization of 4-pyridoxic acid, an emergent renal organic anion transporter 1/3 transporter biomarker.
    Towner J; Rago B; Rodrigues D; Vourvahis M; Holliman C
    Bioanalysis; 2021 Sep; 13(18):1391-1400. PubMed ID: 34551579
    [No Abstract]   [Full Text] [Related]  

  • 13. 6β-Hydroxycortisol is an endogenous probe for evaluation of drug-drug interactions involving a multispecific renal organic anion transporter, OAT3/SLC22A8, in healthy subjects.
    Imamura Y; Tsuruya Y; Damme K; Heer D; Kumagai Y; Maeda K; Murayama N; Okudaira N; Kurihara A; Izumi T; Sugiyama Y; Kusuhara H
    Drug Metab Dispos; 2014 Apr; 42(4):685-94. PubMed ID: 24487120
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Renal expression and function of oat1 and oat3 in rats with vascular calcification.
    Bulacio R; Hazelhoff MH; Torres AM
    Pharmacology; 2012; 90(1-2):66-77. PubMed ID: 22759781
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Drugs interacting with organic anion transporter-1 affect uptake of Tc-99m-mercaptoacetyl-triglycine (MAG3) in the human kidney: therapeutic drug interaction in Tc-99m-MAG3 diagnosis of renal function and possible application of Tc-99m-MAG3 for drug development.
    Takahara N; Saga T; Inubushi M; Kusuhara H; Seki C; Ito S; Oyama N; Yokoyama O; Sugiyama Y; Fujibayashi Y
    Nucl Med Biol; 2013 Jul; 40(5):643-50. PubMed ID: 23618840
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of 1α,25-dihydroxyvitamin D3 , the natural vitamin D receptor ligand, on the pharmacokinetics of cefdinir and cefadroxil, organic anion transporter substrates, in rat.
    Kim YC; Kim IB; Noh CK; Quach HP; Yoon IS; Chow ECY; Kim M; Jin HE; Cho KH; Chung SJ; Pang KS; Maeng HJ
    J Pharm Sci; 2014 Nov; 103(11):3793-3805. PubMed ID: 25266751
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Non randomized study on the potential of nitisinone to inhibit cytochrome P450 2C9, 2D6, 2E1 and the organic anion transporters OAT1 and OAT3 in healthy volunteers.
    Huledal G; Olsson B; Önnestam K; Dalén P; Lindqvist D; Kruse M; Bröijersén A
    Eur J Clin Pharmacol; 2019 Mar; 75(3):313-320. PubMed ID: 30443705
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification and Quantitative Assessment of Uremic Solutes as Inhibitors of Renal Organic Anion Transporters, OAT1 and OAT3.
    Hsueh CH; Yoshida K; Zhao P; Meyer TW; Zhang L; Huang SM; Giacomini KM
    Mol Pharm; 2016 Sep; 13(9):3130-40. PubMed ID: 27467266
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Adaptive responses of renal organic anion transporter 3 (OAT3) during cholestasis.
    Chen J; Terada T; Ogasawara K; Katsura T; Inui K
    Am J Physiol Renal Physiol; 2008 Jul; 295(1):F247-52. PubMed ID: 18480179
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction of human organic anion transporters with various cephalosporin antibiotics.
    Takeda M; Babu E; Narikawa S; Endou H
    Eur J Pharmacol; 2002 Mar; 438(3):137-42. PubMed ID: 11909604
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.