These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 30362380)

  • 1. Computer-aided molecular design of pyrazolotriazines targeting glycogen synthase kinase 3.
    Sciú ML; Sebastián-Pérez V; Martinez-Gonzalez L; Benitez R; Perez DI; Pérez C; Campillo NE; Martinez A; Moyano EL
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):87-96. PubMed ID: 30362380
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and biological evaluation of harmine derivatives as potent GSK-3β/DYRK1A dual inhibitors for the treatment of Alzheimer's disease.
    Liu W; Liu X; Tian L; Gao Y; Liu W; Chen H; Jiang X; Xu Z; Ding H; Zhao Q
    Eur J Med Chem; 2021 Oct; 222():113554. PubMed ID: 34098466
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors.
    Gandini A; Bartolini M; Tedesco D; Martinez-Gonzalez L; Roca C; Campillo NE; Zaldivar-Diez J; Perez C; Zuccheri G; Miti A; Feoli A; Castellano S; Petralla S; Monti B; Rossi M; Moda F; Legname G; Martinez A; Bolognesi ML
    J Med Chem; 2018 Sep; 61(17):7640-7656. PubMed ID: 30078314
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small molecules targeting glycogen synthase kinase 3 as potential drug candidates for the treatment of retinitis pigmentosa.
    Marchena M; Villarejo-Zori B; Zaldivar-Diez J; Palomo V; Gil C; Hernández-Sánchez C; Martínez A; de la Rosa EJ
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):522-526. PubMed ID: 28114834
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Triazolotriazine-Based Dual GSK-3β/CK-1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition.
    Redenti S; Marcovich I; De Vita T; Pérez C; De Zorzi R; Demitri N; Perez DI; Bottegoni G; Bisignano P; Bissaro M; Moro S; Martinez A; Storici P; Spalluto G; Cavalli A; Federico S
    ChemMedChem; 2019 Feb; 14(3):310-314. PubMed ID: 30548443
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of Selective, Substrate-Competitive, and Passive Membrane Permeable Glycogen Synthase Kinase-3β Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling of New C-Glycosylflavones.
    Liang Z; Li QX
    ACS Chem Neurosci; 2018 May; 9(5):1166-1183. PubMed ID: 29381861
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-based optimization of oxadiazole-based GSK-3 inhibitors.
    Lo Monte F; Kramer T; Gu J; Brodrecht M; Pilakowski J; Fuertes A; Dominguez JM; Plotkin B; Eldar-Finkelman H; Schmidt B
    Eur J Med Chem; 2013 Mar; 61():26-40. PubMed ID: 22749643
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, and biological evaluation of 1-phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as new glycogen synthase kinase-3β inhibitors.
    La Pietra V; La Regina G; Coluccia A; Famiglini V; Pelliccia S; Plotkin B; Eldar-Finkelman H; Brancale A; Ballatore C; Crowe A; Brunden KR; Marinelli L; Novellino E; Silvestri R
    J Med Chem; 2013 Dec; 56(24):10066-78. PubMed ID: 24295046
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SLM, a novel carbazole-based fluorophore attenuates okadaic acid-induced tau hyperphosphorylation via down-regulating GSK-3β activity in SH-SY5Y cells.
    Wu X; Kosaraju J; Tam KY
    Eur J Pharm Sci; 2017 Dec; 110():101-108. PubMed ID: 28359686
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of novel glycogen synthase kinase-3α inhibitors: Structure-based virtual screening, preliminary SAR and biological evaluation for treatment of acute myeloid leukemia.
    Wang Y; Dou X; Jiang L; Jin H; Zhang L; Zhang L; Liu Z
    Eur J Med Chem; 2019 Jun; 171():221-234. PubMed ID: 30925338
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glucagon-like peptide-1 protects hippocampal neurons against advanced glycation end product-induced tau hyperphosphorylation.
    Chen S; An FM; Yin L; Liu AR; Yin DK; Yao WB; Gao XD
    Neuroscience; 2014 Jan; 256():137-46. PubMed ID: 24183963
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Temsirolimus attenuates tauopathy in vitro and in vivo by targeting tau hyperphosphorylation and autophagic clearance.
    Jiang T; Yu JT; Zhu XC; Zhang QQ; Cao L; Wang HF; Tan MS; Gao Q; Qin H; Zhang YD; Tan L
    Neuropharmacology; 2014 Oct; 85():121-30. PubMed ID: 24880087
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging.
    Liang SH; Chen JM; Normandin MD; Chang JS; Chang GC; Taylor CK; Trapa P; Plummer MS; Para KS; Conn EL; Lopresti-Morrow L; Lanyon LF; Cook JM; Richter KE; Nolan CE; Schachter JB; Janat F; Che Y; Shanmugasundaram V; Lefker BA; Enerson BE; Livni E; Wang L; Guehl NJ; Patnaik D; Wagner FF; Perlis R; Holson EB; Haggarty SJ; El Fakhri G; Kurumbail RG; Vasdev N
    Angew Chem Int Ed Engl; 2016 Aug; 55(33):9601-5. PubMed ID: 27355874
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase-3α.
    Lo Monte F; Kramer T; Gu J; Anumala UR; Marinelli L; La Pietra V; Novellino E; Franco B; Demedts D; Van Leuven F; Fuertes A; Dominguez JM; Plotkin B; Eldar-Finkelman H; Schmidt B
    J Med Chem; 2012 May; 55(9):4407-24. PubMed ID: 22533818
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core.
    Sivaprakasam P; Han X; Civiello RL; Jacutin-Porte S; Kish K; Pokross M; Lewis HA; Ahmed N; Szapiel N; Newitt JA; Baldwin ET; Xiao H; Krause CM; Park H; Nophsker M; Lippy JS; Burton CR; Langley DR; Macor JE; Dubowchik GM
    Bioorg Med Chem Lett; 2015 May; 25(9):1856-63. PubMed ID: 25845281
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glycogen synthase kinase-3 and its inhibitors: Potential target for various therapeutic conditions.
    Saraswati AP; Ali Hussaini SM; Krishna NH; Babu BN; Kamal A
    Eur J Med Chem; 2018 Jan; 144():843-858. PubMed ID: 29306837
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and evaluation of 8-amino-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives as glycogen synthase kinase-3 (GSK-3) inhibitors.
    Chun K; Park JS; Lee HC; Kim YH; Ye IH; Kim KJ; Ku IW; Noh MY; Cho GW; Kim H; Kim SH; Kim J
    Bioorg Med Chem Lett; 2013 Jul; 23(13):3983-7. PubMed ID: 23683591
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β).
    Zhang P; Hu HR; Bian SH; Huang ZH; Chu Y; Ye DY
    Eur J Med Chem; 2013 Mar; 61():95-103. PubMed ID: 23047001
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanism of zinc-induced phosphorylation of p70 S6 kinase and glycogen synthase kinase 3beta in SH-SY5Y neuroblastoma cells.
    An WL; Bjorkdahl C; Liu R; Cowburn RF; Winblad B; Pei JJ
    J Neurochem; 2005 Mar; 92(5):1104-15. PubMed ID: 15715661
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and biological evaluation of thieno[3,2-c]pyrazol-urea derivatives as potent glycogen synthase kinase 3β inhibitors based on the DFG-out conformation.
    Yan N; Liu HY; Kong TT; Kong ZH; Li LY; Ma X; Zeng YL; Wang MJ; Tang LQ; Zhang CM; Liu ZP; Liu C
    Bioorg Med Chem Lett; 2024 Nov; 112():129932. PubMed ID: 39182737
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.