These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 30366018)

  • 1. Efficient RNA interference-based knockdown of mutant torsinA reveals reversibility of PERK-eIF2α pathway dysregulation in DYT1 transgenic rats in vivo.
    Beauvais G; Watson JL; Aguirre JA; Tecedor L; Ehrlich ME; Gonzalez-Alegre P
    Brain Res; 2019 Mar; 1706():24-31. PubMed ID: 30366018
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Decreased number of striatal cholinergic interneurons and motor deficits in dopamine receptor 2-expressing-cell-specific Dyt1 conditional knockout mice.
    Yokoi F; Oleas J; Xing H; Liu Y; Dexter KM; Misztal C; Gerard M; Efimenko I; Lynch P; Villanueva M; Alsina R; Krishnaswamy S; Vaillancourt DE; Li Y
    Neurobiol Dis; 2020 Feb; 134():104638. PubMed ID: 31618684
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Exploring the Interaction Between eIF2α Dysregulation, Acute Endoplasmic Reticulum Stress and DYT1 Dystonia in the Mammalian Brain.
    Beauvais G; Rodriguez-Losada N; Ying L; Zakirova Z; Watson JL; Readhead B; Gadue P; French DL; Ehrlich ME; Gonzalez-Alegre P
    Neuroscience; 2018 Feb; 371():455-468. PubMed ID: 29289717
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis.
    Beauvais G; Bode NM; Watson JL; Wen H; Glenn KA; Kawano H; Harata NC; Ehrlich ME; Gonzalez-Alegre P
    J Neurosci; 2016 Oct; 36(40):10245-10256. PubMed ID: 27707963
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of the direct pathway in Dyt1 ΔGAG heterozygous knock-in mice and dopamine receptor 1-expressing-cell-specific Dyt1 conditional knockout mice.
    Yokoi F; Chen HX; Oleas J; Dang MT; Xing H; Dexter KM; Li Y
    Behav Brain Res; 2021 Aug; 411():113381. PubMed ID: 34038798
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transcriptional and proteomic profiling in a cellular model of DYT1 dystonia.
    Martin JN; Bair TB; Bode N; Dauer WT; Gonzalez-Alegre P
    Neuroscience; 2009 Dec; 164(2):563-72. PubMed ID: 19665049
    [TBL] [Abstract][Full Text] [Related]  

  • 7. siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells.
    Hewett JW; Nery FC; Niland B; Ge P; Tan P; Hadwiger P; Tannous BA; Sah DW; Breakefield XO
    Hum Mol Genet; 2008 May; 17(10):1436-45. PubMed ID: 18258738
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cell-specific effects of Dyt1 knock-out on sensory processing, network-level connectivity, and motor deficits.
    Wilkes BJ; DeSimone JC; Liu Y; Chu WT; Coombes SA; Li Y; Vaillancourt DE
    Exp Neurol; 2021 Sep; 343():113783. PubMed ID: 34119482
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Altered responses to dopaminergic D2 receptor activation and N-type calcium currents in striatal cholinergic interneurons in a mouse model of DYT1 dystonia.
    Pisani A; Martella G; Tscherter A; Bonsi P; Sharma N; Bernardi G; Standaert DG
    Neurobiol Dis; 2006 Nov; 24(2):318-25. PubMed ID: 16934985
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutant torsinA, which causes early-onset primary torsion dystonia, is redistributed to membranous structures enriched in vesicular monoamine transporter in cultured human SH-SY5Y cells.
    Misbahuddin A; Placzek MR; Taanman JW; Gschmeissner S; Schiavo G; Cooper JM; Warner TT
    Mov Disord; 2005 Apr; 20(4):432-440. PubMed ID: 15593317
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aberrant cellular behavior of mutant torsinA implicates nuclear envelope dysfunction in DYT1 dystonia.
    Gonzalez-Alegre P; Paulson HL
    J Neurosci; 2004 Mar; 24(11):2593-601. PubMed ID: 15028751
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cholinergic dysregulation produced by selective inactivation of the dystonia-associated protein torsinA.
    Sciamanna G; Hollis R; Ball C; Martella G; Tassone A; Marshall A; Parsons D; Li X; Yokoi F; Zhang L; Li Y; Pisani A; Standaert DG
    Neurobiol Dis; 2012 Sep; 47(3):416-27. PubMed ID: 22579992
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dopamine release is impaired in a mouse model of DYT1 dystonia.
    Balcioglu A; Kim MO; Sharma N; Cha JH; Breakefield XO; Standaert DG
    J Neurochem; 2007 Aug; 102(3):783-8. PubMed ID: 17550429
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Membrane defects and genetic redundancy: Are we at a turning point for DYT1 dystonia?
    Cascalho A; Jacquemyn J; Goodchild RE
    Mov Disord; 2017 Mar; 32(3):371-381. PubMed ID: 27911022
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biochemical and cellular analysis of human variants of the DYT1 dystonia protein, TorsinA/TOR1A.
    Hettich J; Ryan SD; de Souza ON; Saraiva Macedo Timmers LF; Tsai S; Atai NA; da Hora CC; Zhang X; Kothary R; Snapp E; Ericsson M; Grundmann K; Breakefield XO; Nery FC
    Hum Mutat; 2014 Sep; 35(9):1101-13. PubMed ID: 24930953
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pre-synaptic release deficits in a DYT1 dystonia mouse model.
    Yokoi F; Cheetham CC; Campbell SL; Sweatt JD; Li Y
    PLoS One; 2013; 8(8):e72491. PubMed ID: 23967309
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The BiP molecular chaperone plays multiple roles during the biogenesis of torsinA, an AAA+ ATPase associated with the neurological disease early-onset torsion dystonia.
    Zacchi LF; Wu HC; Bell SL; Millen L; Paton AW; Paton JC; Thomas PJ; Zolkiewski M; Brodsky JL
    J Biol Chem; 2014 May; 289(18):12727-47. PubMed ID: 24627482
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mislocalization to the nuclear envelope: an effect of the dystonia-causing torsinA mutation.
    Goodchild RE; Dauer WT
    Proc Natl Acad Sci U S A; 2004 Jan; 101(3):847-52. PubMed ID: 14711988
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of endoplasmic reticulum stress reverses synaptic plasticity deficits in striatum of DYT1 dystonia mice.
    Cai H; Ni L; Hu X; Ding X
    Aging (Albany NY); 2021 Aug; 13(16):20319-20334. PubMed ID: 34398825
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel conditional knock-in approach defines molecular and circuit effects of the DYT1 dystonia mutation.
    Weisheit CE; Dauer WT
    Hum Mol Genet; 2015 Nov; 24(22):6459-72. PubMed ID: 26370418
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.