243 related articles for article (PubMed ID: 30366617)
21. Arginine methyltransferase inhibitor 1 inhibits gastric cancer by downregulating eIF4E and targeting PRMT5.
Zhang B; Zhang S; Zhu L; Chen X; Zhao Y; Chao L; Zhou J; Wang X; Zhang X; Ma N
Toxicol Appl Pharmacol; 2017 Dec; 336():1-7. PubMed ID: 28987382
[TBL] [Abstract][Full Text] [Related]
22. Validation of protein arginine methyltransferase 5 (PRMT5) as a candidate therapeutic target in the spontaneous canine model of non-Hodgkin lymphoma.
Sloan SL; Renaldo KA; Long M; Chung JH; Courtney LE; Shilo K; Youssef Y; Schlotter S; Brown F; Klamer BG; Zhang X; Yilmaz AS; Ozer HG; Valli VE; Vaddi K; Scherle P; Alinari L; Kisseberth WC; Baiocchi RA
PLoS One; 2021; 16(5):e0250839. PubMed ID: 33989303
[TBL] [Abstract][Full Text] [Related]
23. Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors.
Zhang WY; Lu WC; Jiang H; Lv ZB; Xie YQ; Lian FL; Liang ZJ; Jiang YX; Wang DJ; Luo C; Jin J; Ye F
Chem Biol Drug Des; 2017 Dec; 90(6):1260-1270. PubMed ID: 28636189
[TBL] [Abstract][Full Text] [Related]
24. Interaction assessments of the first S-adenosylmethionine competitive inhibitor and the essential interacting partner methylosome protein 50 with protein arginine methyltransferase 5 by combined computational methods.
Zhu K; Jiang CS; Hu J; Liu X; Yan X; Tao H; Luo C; Zhang H
Biochem Biophys Res Commun; 2018 Jan; 495(1):721-727. PubMed ID: 29154828
[TBL] [Abstract][Full Text] [Related]
25. The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer.
Quiroz RV; Reutershan MH; Schneider SE; Sloman D; Lacey BM; Swalm BM; Yeung CS; Gibeau C; Spellman DS; Rankic DA; Chen D; Witter D; Linn D; Munsell E; Feng G; Xu H; Hughes JME; Lim J; Saurí J; Geddes K; Wan M; Mansueto MS; Follmer NE; Fier PS; Siliphaivanh P; Daublain P; Palte RL; Hayes RP; Lee S; Kawamura S; Silverman S; Sanyal S; Henderson TJ; Ye Y; Gao Y; Nicholson B; Machacek MR
J Med Chem; 2021 Apr; 64(7):3911-3939. PubMed ID: 33755451
[TBL] [Abstract][Full Text] [Related]
26. Development of an AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases.
Prabhu L; Chen L; Wei H; Demir Ö; Safa A; Zeng L; Amaro RE; O'Neil BH; Zhang ZY; Lu T
Mol Biosyst; 2017 Nov; 13(12):2509-2520. PubMed ID: 29099132
[TBL] [Abstract][Full Text] [Related]
27. Synthesis and Activity of Triazole-Adenosine Analogs as Protein Arginine Methyltransferase 5 Inhibitors.
Brown T; Cao M; Zheng YG
Molecules; 2022 Jun; 27(12):. PubMed ID: 35744905
[TBL] [Abstract][Full Text] [Related]
28. Nucleoside protein arginine methyltransferase 5 (PRMT5) inhibitors.
Lin H; Luengo JI
Bioorg Med Chem Lett; 2019 Jun; 29(11):1264-1269. PubMed ID: 30956011
[TBL] [Abstract][Full Text] [Related]
29. Design and synthesis of novel PRMT1 inhibitors and investigation of their binding preferences using molecular modelling.
Yang H; Ouyang Y; Ma H; Cong H; Zhuang C; Lok WT; Wang Z; Zhu X; Sun Y; Hong W; Wang H
Bioorg Med Chem Lett; 2017 Oct; 27(20):4635-4642. PubMed ID: 28927791
[TBL] [Abstract][Full Text] [Related]
30. Targeting protein arginine methyltransferase 5 in cancers: Roles, inhibitors and mechanisms.
Chen Y; Shao X; Zhao X; Ji Y; Liu X; Li P; Zhang M; Wang Q
Biomed Pharmacother; 2021 Dec; 144():112252. PubMed ID: 34619493
[TBL] [Abstract][Full Text] [Related]
31. Discovery of First-in-Class Protein Arginine Methyltransferase 5 (PRMT5) Degraders.
Shen Y; Gao G; Yu X; Kim H; Wang L; Xie L; Schwarz M; Chen X; Guccione E; Liu J; Bedford MT; Jin J
J Med Chem; 2020 Sep; 63(17):9977-9989. PubMed ID: 32787082
[TBL] [Abstract][Full Text] [Related]
32. Selective small-chemical inhibitors of protein arginine methyltransferase 5 with anti-lung cancer activity.
Kong GM; Yu M; Gu Z; Chen Z; Xu RM; O'Bryant D; Wang Z
PLoS One; 2017; 12(8):e0181601. PubMed ID: 28806746
[TBL] [Abstract][Full Text] [Related]
33. Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation.
Wang C; Jiang H; Jin J; Xie Y; Chen Z; Zhang H; Lian F; Liu YC; Zhang C; Ding H; Chen S; Zhang N; Zhang Y; Jiang H; Chen K; Ye F; Yao Z; Luo C
J Med Chem; 2017 Nov; 60(21):8888-8905. PubMed ID: 29019697
[TBL] [Abstract][Full Text] [Related]
34. Structure-Aided Design, Synthesis, and Biological Evaluation of Potent and Selective Non-Nucleoside Inhibitors Targeting Protein Arginine Methyltransferase 5.
Rong D; Zhou K; Fang W; Yang H; Zhang Y; Shi Q; Huang Y; Li J; Dong H; Li L; Ding J; Huang X; Wang Y
J Med Chem; 2022 Jun; 65(11):7854-7875. PubMed ID: 35612488
[TBL] [Abstract][Full Text] [Related]
35. PRMT1 loss sensitizes cells to PRMT5 inhibition.
Gao G; Zhang L; Villarreal OD; He W; Su D; Bedford E; Moh P; Shen J; Shi X; Bedford MT; Xu H
Nucleic Acids Res; 2019 Jun; 47(10):5038-5048. PubMed ID: 30916320
[TBL] [Abstract][Full Text] [Related]
36. Discovery of tetrahydroisoquinolineindole derivatives as first dual PRMT5 inhibitors/hnRNP E1 upregulators: Design, synthesis and biological evaluation.
Chu WH; Yang N; Zhang JH; Li Y; Song JL; Deng ZP; Meng N; Zhang J; Zhu KK; Jiang CS
Eur J Med Chem; 2023 Oct; 258():115625. PubMed ID: 37429083
[TBL] [Abstract][Full Text] [Related]
37. Research Progress on Small-molecule Inhibitors of Protein Arginine Methyltransferase 5 (PRMT5) for Treating Cancer.
Guo C; Wu L; Zheng X; Zhao L; Hou X; Wang Z; Han C
Curr Top Med Chem; 2023; 23(21):2048-2074. PubMed ID: 37438905
[TBL] [Abstract][Full Text] [Related]
38. EPZ015666, a selective protein arginine methyltransferase 5 (PRMT5) inhibitor with an antitumour effect in retinoblastoma.
Liu X; He J; Mao L; Zhang Y; Cui W; Duan S; Jiang A; Gao Y; Sang Y; Huang G
Exp Eye Res; 2021 Jan; 202():108286. PubMed ID: 33035554
[TBL] [Abstract][Full Text] [Related]
39. PRMT5 Selective Inhibitor Enhances Therapeutic Efficacy of Cisplatin in Lung Cancer Cells.
Bajbouj K; Ramakrishnan RK; Saber-Ayad M; Omar HA; Saheb Sharif-Askari N; Shafarin J; Elmoselhi AB; Ihmaid A; AlHaj Ali S; Alalool A; Abdullah R; Hamid Q
Int J Mol Sci; 2021 Jun; 22(11):. PubMed ID: 34200178
[TBL] [Abstract][Full Text] [Related]
40. Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers.
Prabhu L; Wei H; Chen L; Demir Ö; Sandusky G; Sun E; Wang J; Mo J; Zeng L; Fishel M; Safa A; Amaro R; Korc M; Zhang ZY; Lu T
Oncotarget; 2017 Jun; 8(25):39963-39977. PubMed ID: 28591716
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]