These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 30371865)

  • 1. Heavy Metal Neurotoxicants Induce ALS-Linked TDP-43 Pathology.
    Ash PEA; Dhawan U; Boudeau S; Lei S; Carlomagno Y; Knobel M; Al Mohanna LFA; Boomhower SR; Newland MC; Sherr DH; Wolozin B
    Toxicol Sci; 2019 Jan; 167(1):105-115. PubMed ID: 30371865
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase Separation.
    Wang C; Duan Y; Duan G; Wang Q; Zhang K; Deng X; Qian B; Gu J; Ma Z; Zhang S; Guo L; Liu C; Fang Y
    Mol Cell; 2020 Aug; 79(3):443-458.e7. PubMed ID: 32649883
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inorganic mercury within motor neurons does not cause the TDP-43 changes seen in sporadic ALS.
    Pamphlett R; Kum Jew S
    Toxicol Lett; 2011 Feb; 201(1):58-61. PubMed ID: 21167262
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS.
    Mitchell JC; Constable R; So E; Vance C; Scotter E; Glover L; Hortobagyi T; Arnold ES; Ling SC; McAlonis M; Da Cruz S; Polymenidou M; Tessarolo L; Cleveland DW; Shaw CE
    Acta Neuropathol Commun; 2015 Jun; 3():36. PubMed ID: 26108367
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43.
    Arnold ES; Ling SC; Huelga SC; Lagier-Tourenne C; Polymenidou M; Ditsworth D; Kordasiewicz HB; McAlonis-Downes M; Platoshyn O; Parone PA; Da Cruz S; Clutario KM; Swing D; Tessarollo L; Marsala M; Shaw CE; Yeo GW; Cleveland DW
    Proc Natl Acad Sci U S A; 2013 Feb; 110(8):E736-45. PubMed ID: 23382207
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis.
    Estes PS; Daniel SG; McCallum AP; Boehringer AV; Sukhina AS; Zwick RA; Zarnescu DC
    Dis Model Mech; 2013 May; 6(3):721-33. PubMed ID: 23471911
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43.
    Walker AK; Spiller KJ; Ge G; Zheng A; Xu Y; Zhou M; Tripathy K; Kwong LK; Trojanowski JQ; Lee VM
    Acta Neuropathol; 2015 Nov; 130(5):643-60. PubMed ID: 26197969
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U.
    Tsai KJ; Yang CH; Fang YH; Cho KH; Chien WL; Wang WT; Wu TW; Lin CP; Fu WM; Shen CK
    J Exp Med; 2010 Aug; 207(8):1661-73. PubMed ID: 20660618
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy.
    Turner BJ; Bäumer D; Parkinson NJ; Scaber J; Ansorge O; Talbot K
    BMC Neurosci; 2008 Oct; 9():104. PubMed ID: 18957104
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PABPN1 suppresses TDP-43 toxicity in ALS disease models.
    Chou CC; Alexeeva OM; Yamada S; Pribadi A; Zhang Y; Mo B; Williams KR; Zarnescu DC; Rossoll W
    Hum Mol Genet; 2015 Sep; 24(18):5154-73. PubMed ID: 26130692
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Non-genetically modified models exhibit TARDBP mRNA increase due to perturbed TDP-43 autoregulation.
    Sugai A; Kato T; Koyama A; Koike Y; Konno T; Ishihara T; Onodera O
    Neurobiol Dis; 2019 Oct; 130():104534. PubMed ID: 31310801
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
    Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
    Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Loss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones.
    Highley JR; Kirby J; Jansweijer JA; Webb PS; Hewamadduma CA; Heath PR; Higginbottom A; Raman R; Ferraiuolo L; Cooper-Knock J; McDermott CJ; Wharton SB; Shaw PJ; Ince PG
    Neuropathol Appl Neurobiol; 2014 Oct; 40(6):670-85. PubMed ID: 24750229
    [TBL] [Abstract][Full Text] [Related]  

  • 14. p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS.
    Al-Sarraj S; King A; Troakes C; Smith B; Maekawa S; Bodi I; Rogelj B; Al-Chalabi A; Hortobágyi T; Shaw CE
    Acta Neuropathol; 2011 Dec; 122(6):691-702. PubMed ID: 22101323
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Heterogeneity of cerebral TDP-43 pathology in sporadic amyotrophic lateral sclerosis: Evidence for clinico-pathologic subtypes.
    Takeuchi R; Tada M; Shiga A; Toyoshima Y; Konno T; Sato T; Nozaki H; Kato T; Horie M; Shimizu H; Takebayashi H; Onodera O; Nishizawa M; Kakita A; Takahashi H
    Acta Neuropathol Commun; 2016 Jun; 4(1):61. PubMed ID: 27338935
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies.
    Cascella R; Capitini C; Fani G; Dobson CM; Cecchi C; Chiti F
    J Biol Chem; 2016 Sep; 291(37):19437-48. PubMed ID: 27445339
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis.
    Ishihara T; Ariizumi Y; Shiga A; Kato T; Tan CF; Sato T; Miki Y; Yokoo M; Fujino T; Koyama A; Yokoseki A; Nishizawa M; Kakita A; Takahashi H; Onodera O
    Hum Mol Genet; 2013 Oct; 22(20):4136-47. PubMed ID: 23740936
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An MND/ALS phenotype associated with C9orf72 repeat expansion: abundant p62-positive, TDP-43-negative inclusions in cerebral cortex, hippocampus and cerebellum but without associated cognitive decline.
    Troakes C; Maekawa S; Wijesekera L; Rogelj B; Siklós L; Bell C; Smith B; Newhouse S; Vance C; Johnson L; Hortobágyi T; Shatunov A; Al-Chalabi A; Leigh N; Shaw CE; King A; Al-Sarraj S
    Neuropathology; 2012 Oct; 32(5):505-14. PubMed ID: 22181065
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ALS-linked mutations enlarge TDP-43-enriched neuronal RNA granules in the dendritic arbor.
    Liu-Yesucevitz L; Lin AY; Ebata A; Boon JY; Reid W; Xu YF; Kobrin K; Murphy GJ; Petrucelli L; Wolozin B
    J Neurosci; 2014 Mar; 34(12):4167-74. PubMed ID: 24647938
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The molecular link between inefficient GluA2 Q/R site-RNA editing and TDP-43 pathology in motor neurons of sporadic amyotrophic lateral sclerosis patients.
    Yamashita T; Kwak S
    Brain Res; 2014 Oct; 1584():28-38. PubMed ID: 24355598
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.