These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 30372027)

  • 1. How Does Agonist and Antagonist Binding Lead to Different Conformational Ensemble Equilibria of the κ-Opioid Receptor: Insight from Long-Time Gaussian Accelerated Molecular Dynamics Simulation.
    An X; Bai Q; Bing Z; Zhou S; Shi D; Liu H; Yao X
    ACS Chem Neurosci; 2019 Mar; 10(3):1575-1584. PubMed ID: 30372027
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of kappa opioid receptor mediated, dynorphin-stimulated [35S]GTPγS binding in mouse striatum for the evaluation of selective KOR ligands in an endogenous setting.
    Zhou L; Stahl EL; Lovell KM; Frankowski KJ; Prisinzano TE; Aubé J; Bohn LM
    Neuropharmacology; 2015 Dec; 99():131-41. PubMed ID: 26160155
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular Interaction Between Butorphanol and κ-Opioid Receptor.
    Ji J; Lin W; Vrudhula A; Xi J; Yeliseev A; Grothusen JR; Bu W; Liu R
    Anesth Analg; 2020 Sep; 131(3):935-942. PubMed ID: 32701545
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemotype-selective modes of action of κ-opioid receptor agonists.
    Vardy E; Mosier PD; Frankowski KJ; Wu H; Katritch V; Westkaemper RB; Aubé J; Stevens RC; Roth BL
    J Biol Chem; 2013 Nov; 288(48):34470-83. PubMed ID: 24121503
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor.
    Zheng Z; Huang XP; Mangano TJ; Zou R; Chen X; Zaidi SA; Roth BL; Stevens RC; Katritch V
    J Med Chem; 2017 Apr; 60(7):3070-3081. PubMed ID: 28339199
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Elucidation of conformational states, dynamics, and mechanism of binding in human κ-opioid receptor complexes.
    Leonis G; Avramopoulos A; Salmas RE; Durdagi S; Yurtsever M; Papadopoulos MG
    J Chem Inf Model; 2014 Aug; 54(8):2294-308. PubMed ID: 25060329
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Investigation of the role of βarrestin2 in kappa opioid receptor modulation in a mouse model of pruritus.
    Morgenweck J; Frankowski KJ; Prisinzano TE; Aubé J; Bohn LM
    Neuropharmacology; 2015 Dec; 99():600-9. PubMed ID: 26318102
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Docking and free energy perturbation studies of ligand binding in the kappa opioid receptor.
    Goldfeld DA; Murphy R; Kim B; Wang L; Beuming T; Abel R; Friesner RA
    J Phys Chem B; 2015 Jan; 119(3):824-35. PubMed ID: 25395044
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural Characterization of KOR Inactive and Active States for 3D Pharmacology and Drug Discovery.
    Zaidi SA; Katritch V
    Handb Exp Pharmacol; 2022; 271():41-64. PubMed ID: 33945028
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Revealing the Positive Binding Cooperativity Mechanism between the Orthosteric and the Allosteric Antagonists of CCR2 by Metadynamics and Gaussian Accelerated Molecular Dynamics Simulations.
    An X; Bai Q; Bing Z; Liu H; Zhang Q; Liu H; Yao X
    ACS Chem Neurosci; 2020 Feb; 11(4):628-637. PubMed ID: 31968162
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Current κ opioid receptor ligands and discovery of a new molecular scaffold as a κ opioid receptor antagonist using pharmacophore-based virtual screening.
    Spetea M; Asim MF; Noha S; Wolber G; Schmidhammer H
    Curr Pharm Des; 2013; 19(42):7362-72. PubMed ID: 23448472
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class of Structurally Distinct, Selective Kappa Opioid Ligands.
    Spetea M; Schmidhammer H
    Handb Exp Pharmacol; 2022; 271():163-195. PubMed ID: 33454858
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, opioid receptor binding, and bioassay of naltrindole analogues substituted in the indolic benzene moiety.
    Ananthan S; Johnson CA; Carter RL; Clayton SD; Rice KC; Xu H; Davis P; Porreca F; Rothman RB
    J Med Chem; 1998 Jul; 41(15):2872-81. PubMed ID: 9667975
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of Diphenethylamines as Selective Kappa Opioid Receptor Ligands and Their Pharmacological Activities.
    Schmidhammer H; Erli F; Guerrieri E; Spetea M
    Molecules; 2020 Nov; 25(21):. PubMed ID: 33147885
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nalfurafine is a G-protein biased agonist having significantly greater bias at the human than rodent form of the kappa opioid receptor.
    Schattauer SS; Kuhar JR; Song A; Chavkin C
    Cell Signal; 2017 Apr; 32():59-65. PubMed ID: 28088389
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacodynamic Relationships between Duration of Action of JDTic-like Kappa-Opioid Receptor Antagonists and Their Brain and Plasma Pharmacokinetics in Rats.
    Owens SM; Pollard GT; Howard JL; Fennell TR; Snyder RW; Carroll FI
    ACS Chem Neurosci; 2016 Dec; 7(12):1737-1745. PubMed ID: 27700049
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance.
    Xu M; Petraschka M; McLaughlin JP; Westenbroek RE; Caron MG; Lefkowitz RJ; Czyzyk TA; Pintar JE; Terman GW; Chavkin C
    J Neurosci; 2004 May; 24(19):4576-84. PubMed ID: 15140929
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kinase cascades and ligand-directed signaling at the kappa opioid receptor.
    Bruchas MR; Chavkin C
    Psychopharmacology (Berl); 2010 Jun; 210(2):137-47. PubMed ID: 20401607
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Agonist activity of naloxone benzoylhydrazone at recombinant and native opioid receptors.
    Olianas MC; Concas D; Onali P
    Br J Pharmacol; 2006 Feb; 147(4):360-70. PubMed ID: 16402046
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.
    Che T; Majumdar S; Zaidi SA; Ondachi P; McCorvy JD; Wang S; Mosier PD; Uprety R; Vardy E; Krumm BE; Han GW; Lee MY; Pardon E; Steyaert J; Huang XP; Strachan RT; Tribo AR; Pasternak GW; Carroll FI; Stevens RC; Cherezov V; Katritch V; Wacker D; Roth BL
    Cell; 2018 Jan; 172(1-2):55-67.e15. PubMed ID: 29307491
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.