697 related articles for article (PubMed ID: 30373799)
1. Preclinical Characterization of NVR 3-778, a First-in-Class Capsid Assembly Modulator against Hepatitis B Virus.
Lam AM; Espiritu C; Vogel R; Ren S; Lau V; Kelly M; Kuduk SD; Hartman GD; Flores OA; Klumpp K
Antimicrob Agents Chemother; 2019 Jan; 63(1):. PubMed ID: 30373799
[TBL] [Abstract][Full Text] [Related]
2. Effect of Plasma Protein Binding on the Anti-Hepatitis B Virus Activity and Pharmacokinetic Properties of NVR 3-778.
Helsen N; Vervoort T; Vandenbossche J; Lenz O; Monshouwer M; Pauwels F; Snoeys J
Antimicrob Agents Chemother; 2018 Nov; 62(11):. PubMed ID: 30181376
[TBL] [Abstract][Full Text] [Related]
3. Antiviral Activity, Safety, and Pharmacokinetics of Capsid Assembly Modulator NVR 3-778 in Patients with Chronic HBV Infection.
Yuen MF; Gane EJ; Kim DJ; Weilert F; Yuen Chan HL; Lalezari J; Hwang SG; Nguyen T; Flores O; Hartman G; Liaw S; Lenz O; Kakuda TN; Talloen W; Schwabe C; Klumpp K; Brown N
Gastroenterology; 2019 Apr; 156(5):1392-1403.e7. PubMed ID: 30625297
[TBL] [Abstract][Full Text] [Related]
4. Preclinical Profile of AB-423, an Inhibitor of Hepatitis B Virus Pregenomic RNA Encapsidation.
Mani N; Cole AG; Phelps JR; Ardzinski A; Cobarrubias KD; Cuconati A; Dorsey BD; Evangelista E; Fan K; Guo F; Guo H; Guo JT; Harasym TO; Kadhim S; Kultgen SG; Lee ACH; Li AHL; Long Q; Majeski SA; Mao R; McClintock KD; Reid SP; Rijnbrand R; Snead NM; Micolochick Steuer HM; Stever K; Tang S; Wang X; Zhao Q; Sofia MJ
Antimicrob Agents Chemother; 2018 Jun; 62(6):. PubMed ID: 29555628
[TBL] [Abstract][Full Text] [Related]
5. Capsid Assembly Modulators Have a Dual Mechanism of Action in Primary Human Hepatocytes Infected with Hepatitis B Virus.
Berke JM; Dehertogh P; Vergauwen K; Van Damme E; Mostmans W; Vandyck K; Pauwels F
Antimicrob Agents Chemother; 2017 Aug; 61(8):. PubMed ID: 28584155
[TBL] [Abstract][Full Text] [Related]
6. Hepatitis B Virus Capsid Assembly Modulators, but Not Nucleoside Analogs, Inhibit the Production of Extracellular Pregenomic RNA and Spliced RNA Variants.
Lam AM; Ren S; Espiritu C; Kelly M; Lau V; Zheng L; Hartman GD; Flores OA; Klumpp K
Antimicrob Agents Chemother; 2017 Aug; 61(8):. PubMed ID: 28559265
[TBL] [Abstract][Full Text] [Related]
7. Identification and characterization of a novel hepatitis B virus pregenomic RNA encapsidation inhibitor.
Jo E; Ryu DK; König A; Park S; Cho Y; Park SH; Kim TH; Yoon SK; Ryu WS; Cechetto J; Windisch MP
Antiviral Res; 2020 Mar; 175():104709. PubMed ID: 31940474
[TBL] [Abstract][Full Text] [Related]
8. Antiviral Properties and Mechanism of Action Studies of the Hepatitis B Virus Capsid Assembly Modulator JNJ-56136379.
Berke JM; Dehertogh P; Vergauwen K; Mostmans W; Vandyck K; Raboisson P; Pauwels F
Antimicrob Agents Chemother; 2020 Apr; 64(5):. PubMed ID: 32094138
[TBL] [Abstract][Full Text] [Related]
9. Preclinical characterization of AB-506, an inhibitor of HBV replication targeting the viral core protein.
Mani N; Cole AG; Phelps JR; Ardzinski A; Burns R; Chiu T; Cuconati A; Dorsey BD; Evangelista E; Fan K; Guo F; Harasym TO; Kadhim S; Kowalski R; Kultgen SG; Lee ACH; Li AH; Majeski SA; Miller A; Pasetka C; Reid SP; Rijnbrand R; Micolochick Steuer HM; Stever K; Tang S; Teng X; Wang X; Sofia MJ
Antiviral Res; 2022 Jan; 197():105211. PubMed ID: 34826506
[TBL] [Abstract][Full Text] [Related]
10. Novel Potent Capsid Assembly Modulators Regulate Multiple Steps of the Hepatitis B Virus Life Cycle.
Lahlali T; Berke JM; Vergauwen K; Foca A; Vandyck K; Pauwels F; Zoulim F; Durantel D
Antimicrob Agents Chemother; 2018 Oct; 62(10):. PubMed ID: 30012770
[TBL] [Abstract][Full Text] [Related]
11. Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection.
Klumpp K; Shimada T; Allweiss L; Volz T; Lütgehetmann M; Hartman G; Flores OA; Lam AM; Dandri M
Gastroenterology; 2018 Feb; 154(3):652-662.e8. PubMed ID: 29079518
[TBL] [Abstract][Full Text] [Related]
12. SAR studies in the sulfonyl carboxamide class of HBV capsid assembly modulators.
Kuduk SD; Lam AM; Espiritu C; Vogel R; Lau V; Klumpp K; Flores OA; Hartman GD
Bioorg Med Chem Lett; 2019 Aug; 29(16):2405-2409. PubMed ID: 31227344
[TBL] [Abstract][Full Text] [Related]
13. Hepatitis B Virus Core Protein Dephosphorylation Occurs during Pregenomic RNA Encapsidation.
Zhao Q; Hu Z; Cheng J; Wu S; Luo Y; Chang J; Hu J; Guo JT
J Virol; 2018 Jul; 92(13):. PubMed ID: 29669831
[TBL] [Abstract][Full Text] [Related]
14. A New Role for Capsid Assembly Modulators To Target Mature Hepatitis B Virus Capsids and Prevent Virus Infection.
Ko C; Bester R; Zhou X; Xu Z; Blossey C; Sacherl J; Vondran FWR; Gao L; Protzer U
Antimicrob Agents Chemother; 2019 Dec; 64(1):. PubMed ID: 31658963
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, and biological evaluation of novel sulfamoylbenzamide derivatives as HBV capsid assembly modulators.
Wang S; Ren Y; Li Q; Wang Y; Jiang X; Xu S; Zhang X; Zhao S; Bradley DP; Woodson ME; Zhao F; Wu S; Li Y; Tian Y; Liu X; Tavis JE; Zhan P
Bioorg Chem; 2022 Dec; 129():106192. PubMed ID: 36265355
[TBL] [Abstract][Full Text] [Related]
16. Naturally occurring core protein mutations compensate for the reduced replication fitness of a lamivudine-resistant HBV isolate.
Zhang Y; Zhang H; Zhang J; Zhang J; Guo H
Antiviral Res; 2019 May; 165():47-54. PubMed ID: 30902704
[TBL] [Abstract][Full Text] [Related]
17. Sulfamoylbenzamide derivatives inhibit the assembly of hepatitis B virus nucleocapsids.
Campagna MR; Liu F; Mao R; Mills C; Cai D; Guo F; Zhao X; Ye H; Cuconati A; Guo H; Chang J; Xu X; Block TM; Guo JT
J Virol; 2013 Jun; 87(12):6931-42. PubMed ID: 23576513
[TBL] [Abstract][Full Text] [Related]
18. Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly.
Kang JA; Kim S; Park M; Park HJ; Kim JH; Park S; Hwang JR; Kim YC; Jun Kim Y; Cho Y; Sun Jin M; Park SG
Nat Commun; 2019 May; 10(1):2184. PubMed ID: 31097716
[TBL] [Abstract][Full Text] [Related]
19. Identification of hepatitis B virus core protein residues critical for capsid assembly, pgRNA encapsidation and resistance to capsid assembly modulators.
Luo Y; Cheng J; Hu Z; Ban H; Wu S; Hwang N; Kulp J; Li Y; Du Y; Chang J; Viswanathan U; Guo JT
Antiviral Res; 2021 Jul; 191():105080. PubMed ID: 33933516
[TBL] [Abstract][Full Text] [Related]
20. Characterization of a Novel Capsid Assembly Modulator for the Treatment of Chronic Hepatitis B Virus Infection.
Burdette D; Hyrina A; Song Z; Beran RK; Cheung T; Gilmore S; Kobayashi T; Li L; Liu Y; Niedziela-Majka A; Medley J; Mehra U; Morganelli P; Novikov N; Niu C; Tam D; Tang J; Wang J; Yue Q; Fletcher SP; Holdorf MM; Delaney WE; Feierbach B; Lazerwith S
Antimicrob Agents Chemother; 2023 Jan; 67(1):e0134822. PubMed ID: 36519892
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]