84 related articles for article (PubMed ID: 30377696)
1. [Research progress on pathophysiological function of SOS1 protein].
Hao PQ; Zhang XY; Guo H; Yang Y; An S; Liu Y; Guo XX; Xu TR; Hao Q
Sheng Li Xue Bao; 2018 Oct; 70(5):565-570. PubMed ID: 30377696
[TBL] [Abstract][Full Text] [Related]
2. Understanding SOS (Son of Sevenless).
Pierre S; Bats AS; Coumoul X
Biochem Pharmacol; 2011 Nov; 82(9):1049-56. PubMed ID: 21787760
[TBL] [Abstract][Full Text] [Related]
3. SOS1 over-expression in genital skin fibroblasts from hirsute women: a putative role of the SOS1/RAS pathway in the pathogenesis of hirsutism.
Minella D; Wannenes F; Biancolella M; Amati F; Testa B; Nardone A; Bueno S; Fabbri A; Lauro D; Novelli G; Moretti C
J Biol Regul Homeost Agents; 2011; 25(4):615-26. PubMed ID: 22217993
[TBL] [Abstract][Full Text] [Related]
4. Development of Son of Sevenless Homologue 1 (SOS1) Modulators To Treat Cancers by Regulating RAS Signaling.
Luo G; Wang B; Hou Q; Wu X
J Med Chem; 2023 Apr; 66(7):4324-4341. PubMed ID: 36987571
[TBL] [Abstract][Full Text] [Related]
5. SOS2 Comes to the Fore: Differential Functionalities in Physiology and Pathology.
Baltanás FC; García-Navas R; Santos E
Int J Mol Sci; 2021 Jun; 22(12):. PubMed ID: 34205562
[TBL] [Abstract][Full Text] [Related]
6. CIIA negatively regulates the Ras-Erk1/2 signaling pathway through inhibiting the Ras-specific GEF activity of SOS1.
Hwang HS; Hwang SG; Yoon KW; Yoon JH; Roh KH; Choi EJ
J Cell Sci; 2014 Apr; 127(Pt 8):1640-6. PubMed ID: 24522193
[TBL] [Abstract][Full Text] [Related]
7. Small molecule Son of Sevenless 1 (SOS1) inhibitors: a review of the patent literature.
Thompson SK; Buckl A; Dossetter AG; Griffen E; Gill A
Expert Opin Ther Pat; 2021 Dec; 31(12):1189-1204. PubMed ID: 34253125
[No Abstract] [Full Text] [Related]
8. Structural characterization of 14-3-3ζ in complex with the human Son of sevenless homolog 1 (SOS1).
Ballone A; Centorrino F; Wolter M; Ottmann C
J Struct Biol; 2018 Jun; 202(3):210-215. PubMed ID: 29408703
[TBL] [Abstract][Full Text] [Related]
9. A novel SOS1 mutation in Costello/CFC syndrome affects signaling in both RAS and PI3K pathways.
Tumurkhuu M; Saitoh M; Takita J; Mizuno Y; Mizuguchi M
J Recept Signal Transduct Res; 2013 Apr; 33(2):124-8. PubMed ID: 23528009
[TBL] [Abstract][Full Text] [Related]
10. The two hats of SOS.
Nimnual A; Bar-Sagi D
Sci STKE; 2002 Aug; 2002(145):pe36. PubMed ID: 12177507
[TBL] [Abstract][Full Text] [Related]
11. Sos1 disruption impairs cellular proliferation and viability through an increase in mitochondrial oxidative stress in primary MEFs.
Liceras-Boillos P; García-Navas R; Ginel-Picardo A; Anta B; Pérez-Andrés M; Lillo C; Gómez C; Jimeno D; Fernández-Medarde A; Baltanás FC; Santos E
Oncogene; 2016 Dec; 35(50):6389-6402. PubMed ID: 27157612
[TBL] [Abstract][Full Text] [Related]
12. Targeting Son of Sevenless 1: The pacemaker of KRAS.
Kessler D; Gerlach D; Kraut N; McConnell DB
Curr Opin Chem Biol; 2021 Jun; 62():109-118. PubMed ID: 33848766
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of Son of Sevenless Homologue 1 (SOS1): Promising therapeutic treatment for KRAS-mutant cancers.
Chen T; Tang X; Wang Z; Feng F; Xu C; Zhao Q; Wu Y; Sun H; Chen Y
Eur J Med Chem; 2023 Dec; 261():115828. PubMed ID: 37778239
[TBL] [Abstract][Full Text] [Related]
14. SOS1-inspired hydrocarbon-stapled peptide as a pan-Ras inhibitor.
Li A; Li X; Zou J; Zhuo X; Chen S; Chai X; Gai C; Xu W; Zhao Q; Zou Y
Bioorg Chem; 2023 Jun; 135():106500. PubMed ID: 37003134
[TBL] [Abstract][Full Text] [Related]
15. Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling.
Oh-hora M; Johmura S; Hashimoto A; Hikida M; Kurosaki T
J Exp Med; 2003 Dec; 198(12):1841-51. PubMed ID: 14676298
[TBL] [Abstract][Full Text] [Related]
16. Current advances and development strategies of targeting son of sevenless 1 (SOS1) in drug discovery.
Wu J; Li X; Wu C; Wang Y; Zhang J
Eur J Med Chem; 2024 Mar; 268():116282. PubMed ID: 38430853
[TBL] [Abstract][Full Text] [Related]
17. Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices.
Leshchiner ES; Parkhitko A; Bird GH; Luccarelli J; Bellairs JA; Escudero S; Opoku-Nsiah K; Godes M; Perrimon N; Walensky LD
Proc Natl Acad Sci U S A; 2015 Feb; 112(6):1761-6. PubMed ID: 25624485
[TBL] [Abstract][Full Text] [Related]
18. Induction of the Ras activator Son of Sevenless 1 by environmental pollutants mediates their effects on cellular proliferation.
Pierre S; Bats AS; Chevallier A; Bui LC; Ambolet-Camoit A; Garlatti M; Aggerbeck M; Barouki R; Coumoul X
Biochem Pharmacol; 2011 Jan; 81(2):304-13. PubMed ID: 20950586
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and biological evaluation of quinazoline SOS1 inhibitors.
Jiang H; Fan Y; Wang X; Wang J; Yang H; Fan W; Tang C
Bioorg Med Chem Lett; 2023 May; 88():129265. PubMed ID: 37011767
[TBL] [Abstract][Full Text] [Related]
20. Sos1 rapidly associates with Grb2 and is hypophosphorylated when complexed with the EGF receptor after EGF stimulation.
Hu Y; Bowtell DD
Oncogene; 1996 May; 12(9):1865-72. PubMed ID: 8649846
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
