122 related articles for article (PubMed ID: 30392427)
1. Kinetics of dextromethorphan-O-demethylase activity and distribution of CYP2D in four commonly-used subcellular fractions of rat brain.
DuBois BN; Amirrad F; Mehvar R
Xenobiotica; 2019 Oct; 49(10):1133-1142. PubMed ID: 30392427
[TBL] [Abstract][Full Text] [Related]
2. UPLC-MS/MS analysis of dextromethorphan-O-demethylation kinetics in rat brain microsomes.
DuBois BN; Mehvar R
J Chromatogr B Analyt Technol Biomed Life Sci; 2018 Oct; 1096():66-72. PubMed ID: 30149296
[TBL] [Abstract][Full Text] [Related]
3. Dextromethorphan O-demethylase activity in rat brain microsomes.
Jolivalt C; Minn A; Vincent-Viry M; Galteau MM; Siest G
Neurosci Lett; 1995 Feb; 187(1):65-8. PubMed ID: 7617305
[TBL] [Abstract][Full Text] [Related]
4. Regional and cellular distribution of CYP2D subfamily members in rat brain.
Miksys S; Rao Y; Sellers EM; Kwan M; Mendis D; Tyndale RF
Xenobiotica; 2000 Jun; 30(6):547-64. PubMed ID: 10923858
[TBL] [Abstract][Full Text] [Related]
5. Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes.
Di Marco A; Yao D; Laufer R
Eur J Biochem; 2003 Sep; 270(18):3768-77. PubMed ID: 12950260
[TBL] [Abstract][Full Text] [Related]
6. Effect of quinidine on the dextromethorphan O-demethylase activity of microsomal fractions from human liver.
Broly F; Libersa C; Lhermitte M; Bechtel P; Dupuis B
Br J Clin Pharmacol; 1989 Jul; 28(1):29-36. PubMed ID: 2775613
[TBL] [Abstract][Full Text] [Related]
7. The effect of ageing and cerebral serotonin deficit on the activity of cytochrome P450 2D (CYP2D) in the brain and liver of male rats.
Haduch A; Pukło R; Alenina N; Nikiforuk A; Popik P; Bader M; Daniel WA
Neurochem Int; 2020 Dec; 141():104884. PubMed ID: 33091481
[TBL] [Abstract][Full Text] [Related]
8. Characterization of cytochrome P-450 2D1 activity in rat brain: high-affinity kinetics for dextromethorphan.
Tyndale RF; Li Y; Li NY; Messina E; Miksys S; Sellers EM
Drug Metab Dispos; 1999 Aug; 27(8):924-30. PubMed ID: 10421620
[TBL] [Abstract][Full Text] [Related]
9. In vivo administration of H2 blockers, cimetidine and ranitidine, reduced the contents of the cytochrome P450IID (CYP2D) subfamily and their activities in rat liver microsomes.
Orishiki M; Matsuo Y; Nishioka M; Ichikawa Y
Int J Biochem; 1994 Jun; 26(6):751-8. PubMed ID: 8063004
[TBL] [Abstract][Full Text] [Related]
10. Primary and secondary oxidative metabolism of dextromethorphan. In vitro studies with female Sprague-Dawley and Dark Agouti rat liver microsomes.
Kerry NL; Somogyi AA; Mikus G; Bochner F
Biochem Pharmacol; 1993 Feb; 45(4):833-9. PubMed ID: 8452558
[TBL] [Abstract][Full Text] [Related]
11. Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities?
Yu A; Haining RL
Drug Metab Dispos; 2001 Nov; 29(11):1514-20. PubMed ID: 11602530
[TBL] [Abstract][Full Text] [Related]
12. Imipramine-induced inactivation of a cytochrome P450 2D enzyme in rat liver microsomes: in relation to covalent binding of its reactive intermediate.
Masubuchi Y; Igarashi S; Suzuki T; Horie T; Narimatsu S
J Pharmacol Exp Ther; 1996 Nov; 279(2):724-31. PubMed ID: 8930177
[TBL] [Abstract][Full Text] [Related]
13. Consequences of daily corticosteroid dosing with or without pre-treatment with quinidine on the in vivo cytochrome P450 2D (CYP2D) enzyme in rats: effect on O-demethylation activity of dextromethorphan and expression levels of CYP2D1 mRNA.
Giri P; Delvadia P; Gupta L; Patel N; Trivedi P; Lad K; Patel HM; Srinivas NR
Xenobiotica; 2018 Jan; 48(1):1-10. PubMed ID: 28010169
[TBL] [Abstract][Full Text] [Related]
14. High-performance liquid chromatographic assays for bufuralol 1'-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver.
Kronbach T; Mathys D; Gut J; Catin T; Meyer UA
Anal Biochem; 1987 Apr; 162(1):24-32. PubMed ID: 3605590
[TBL] [Abstract][Full Text] [Related]
15. Brain cytochrome P450 and testosterone metabolism by rat brain subcellular fractions: presence of cytochrome P450 3A immunoreactive protein in rat brain mitochondria.
Jayyosi Z; Cooper KO; Thomas PE
Arch Biochem Biophys; 1992 Oct; 298(1):265-70. PubMed ID: 1524436
[TBL] [Abstract][Full Text] [Related]
16. The activity of brain and liver cytochrome P450 2D (CYP2D) is differently affected by antidepressants in the chronic mild stress (CMS) model of depression in the rat.
Haduch A; Rysz M; Papp M; Daniel WA
Biochem Pharmacol; 2018 Oct; 156():398-405. PubMed ID: 30195732
[TBL] [Abstract][Full Text] [Related]
17. The effect of cimetidine on dextromethorphan O-demethylase activity of human liver microsomes and recombinant CYP2D6.
Madeira M; Levine M; Chang TK; Mirfazaelian A; Bellward GD
Drug Metab Dispos; 2004 Apr; 32(4):460-7. PubMed ID: 16680870
[TBL] [Abstract][Full Text] [Related]
18. Sigmoidal kinetics of CYP3A substrates: an approach for scaling dextromethorphan metabolism in hepatic microsomes and isolated hepatocytes to predict in vivo clearance in rat.
Witherow LE; Houston JB
J Pharmacol Exp Ther; 1999 Jul; 290(1):58-65. PubMed ID: 10381760
[TBL] [Abstract][Full Text] [Related]
19. Brain mitochondrial cytochromes P450: xenobiotic metabolism, presence of multiple forms and their selective inducibility.
Bhagwat SV; Boyd MR; Ravindranath V
Arch Biochem Biophys; 1995 Jun; 320(1):73-83. PubMed ID: 7793987
[TBL] [Abstract][Full Text] [Related]
20. The potential for CYP2D6 inhibition screening using a novel scintillation proximity assay-based approach.
Delaporte E; Slaughter DE; Egan MA; Gatto GJ; Santos A; Shelley J; Price E; Howells L; Dean DC; Rodrigues AD
J Biomol Screen; 2001 Aug; 6(4):225-31. PubMed ID: 11689122
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
