172 related articles for article (PubMed ID: 30398879)
1. Peripherally Restricted, Highly Potent, Selective, Aqueous-Soluble EP2 Antagonist with Anti-Inflammatory Properties.
Ganesh T; Banik A; Dingledine R; Wang W; Amaradhi R
Mol Pharm; 2018 Dec; 15(12):5809-5817. PubMed ID: 30398879
[TBL] [Abstract][Full Text] [Related]
2. Potent, Selective, Water Soluble, Brain-Permeable EP2 Receptor Antagonist for Use in Central Nervous System Disease Models.
Amaradhi R; Banik A; Mohammed S; Patro V; Rojas A; Wang W; Motati DR; Dingledine R; Ganesh T
J Med Chem; 2020 Feb; 63(3):1032-1050. PubMed ID: 31904232
[TBL] [Abstract][Full Text] [Related]
3. Lead optimization studies of cinnamic amide EP2 antagonists.
Ganesh T; Jiang J; Yang MS; Dingledine R
J Med Chem; 2014 May; 57(10):4173-84. PubMed ID: 24773616
[TBL] [Abstract][Full Text] [Related]
4. Differential expression of E-type prostanoid receptors 2 and 4 in microglia stimulated with lipopolysaccharide.
Bonfill-Teixidor E; Otxoa-de-Amezaga A; Font-Nieves M; Sans-Fons MG; Planas AM
J Neuroinflammation; 2017 Jan; 14(1):3. PubMed ID: 28086956
[TBL] [Abstract][Full Text] [Related]
5. A Novel Second-Generation EP2 Receptor Antagonist Reduces Neuroinflammation and Gliosis After Status Epilepticus in Rats.
Rojas A; Amaradhi R; Banik A; Jiang C; Abreu-Melon J; Wang S; Dingledine R; Ganesh T
Neurotherapeutics; 2021 Apr; 18(2):1207-1225. PubMed ID: 33410110
[TBL] [Abstract][Full Text] [Related]
6. Expression of trophoblast derived prostaglandin E2 receptor 2 (EP2) is reduced in patients with recurrent miscarriage and EP2 regulates cell proliferation and expression of inflammatory cytokines.
Peng L; Ye Y; Mullikin H; Lin L; Kuhn C; Rahmeh M; Mahner S; Jeschke U; von Schönfeldt V
J Reprod Immunol; 2020 Nov; 142():103210. PubMed ID: 33011635
[TBL] [Abstract][Full Text] [Related]
7. Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2.
Jiang J; Ganesh T; Du Y; Quan Y; Serrano G; Qui M; Speigel I; Rojas A; Lelutiu N; Dingledine R
Proc Natl Acad Sci U S A; 2012 Feb; 109(8):3149-54. PubMed ID: 22323596
[TBL] [Abstract][Full Text] [Related]
8. Prostanoid receptors EP2, EP4, and FP are regulated by estradiol in bovine oviductal smooth muscle.
Huang N; Liu B; Dong Z; Mao W; Zhang N; Li C; Cao J
Prostaglandins Other Lipid Mediat; 2015 Sep; 121(Pt B):170-5. PubMed ID: 26319698
[TBL] [Abstract][Full Text] [Related]
9. Characterization of the EP receptor subtype that mediates the inhibitory effects of prostaglandin E2 on IgE-dependent secretion from human lung mast cells.
Kay LJ; Gilbert M; Pullen N; Skerratt S; Farrington J; Seward EP; Peachell PT
Clin Exp Allergy; 2013 Jul; 43(7):741-51. PubMed ID: 23786281
[TBL] [Abstract][Full Text] [Related]
10. EP
Bradbury P; Rumzhum NN; Ammit AJ
J Cell Physiol; 2019 Jul; 234(7):11070-11077. PubMed ID: 30536718
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: involvement of protein kinase C-θ activation.
Takahashi T; Uehara H; Ogawa H; Umemoto H; Bando Y; Izumi K
Oncotarget; 2015 Mar; 6(7):4829-44. PubMed ID: 25638159
[TBL] [Abstract][Full Text] [Related]
12. Second-Generation Prostaglandin Receptor EP2 Antagonist, TG8-260, with High Potency, Selectivity, Oral Bioavailability, and Anti-Inflammatory Properties.
Amaradhi R; Mohammed S; Banik A; Franklin R; Dingledine R; Ganesh T
ACS Pharmacol Transl Sci; 2022 Feb; 5(2):118-133. PubMed ID: 35187419
[TBL] [Abstract][Full Text] [Related]
13. CD40 engagement on dendritic cells induces cyclooxygenase-2 and EP2 receptor via p38 and ERK MAPKs.
Harizi H; Limem I; Gualde N
Immunol Cell Biol; 2011 Feb; 89(2):275-82. PubMed ID: 20697426
[TBL] [Abstract][Full Text] [Related]
14. Prostaglandin E2-induced inflammation: Relevance of prostaglandin E receptors.
Kawahara K; Hohjoh H; Inazumi T; Tsuchiya S; Sugimoto Y
Biochim Biophys Acta; 2015 Apr; 1851(4):414-21. PubMed ID: 25038274
[TBL] [Abstract][Full Text] [Related]
15. Prostaglandin E2 inhibits mast cell-dependent bronchoconstriction in human small airways through the E prostanoid subtype 2 receptor.
Säfholm J; Manson ML; Bood J; Delin I; Orre AC; Bergman P; Al-Ameri M; Dahlén SE; Adner M
J Allergy Clin Immunol; 2015 Nov; 136(5):1232-9.e1. PubMed ID: 25962903
[TBL] [Abstract][Full Text] [Related]
16. Prostaglandin E2 represses interleukin 1 beta-induced inflammatory mediator output from pregnant human myometrial cells through the EP2 and EP4 receptors.
Mosher AA; Rainey KJ; Giembycz MA; Wood S; Slater DM
Biol Reprod; 2012 Jul; 87(1):7, 1-10. PubMed ID: 22517618
[TBL] [Abstract][Full Text] [Related]
17. Prostaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotection.
Jiang J; Dingledine R
Trends Pharmacol Sci; 2013 Jul; 34(7):413-23. PubMed ID: 23796953
[TBL] [Abstract][Full Text] [Related]
18. Concerted EP2 and EP4 Receptor Signaling Stimulates Autocrine Prostaglandin E
Mangelsen E; Rothe M; Schulz A; Kourpa A; Panáková D; Kreutz R; Bolbrinker J
Cells; 2020 May; 9(5):. PubMed ID: 32438662
[TBL] [Abstract][Full Text] [Related]
19. Selective inhibition of prostaglandin E2 receptors EP2 and EP4 modulates DNA methylation and histone modification machinery proteins in human endometriotic cells.
Arosh JA; Lee J; Starzinski-Powitz A; Banu SK
Mol Cell Endocrinol; 2015 Jul; 409():51-8. PubMed ID: 25843056
[TBL] [Abstract][Full Text] [Related]
20. Molecular and preclinical basis to inhibit PGE2 receptors EP2 and EP4 as a novel nonsteroidal therapy for endometriosis.
Arosh JA; Lee J; Balasubbramanian D; Stanley JA; Long CR; Meagher MW; Osteen KG; Bruner-Tran KL; Burghardt RC; Starzinski-Powitz A; Banu SK
Proc Natl Acad Sci U S A; 2015 Aug; 112(31):9716-21. PubMed ID: 26199416
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
