BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

320 related articles for article (PubMed ID: 30399392)

  • 1. Heterozygous huntingtin promotes cadmium neurotoxicity and neurodegeneration in striatal cells via altered metal transport and protein kinase C delta dependent oxidative stress and apoptosis signaling mechanisms.
    Kwakye GF; Jiménez JA; Thomas MG; Kingsley BA; McIIvin M; Saito MA; Korley EM
    Neurotoxicology; 2019 Jan; 70():48-61. PubMed ID: 30399392
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Acute exposure to chlorpyrifos caused NADPH oxidase mediated oxidative stress and neurotoxicity in a striatal cell model of Huntington's disease.
    Dominah GA; McMinimy RA; Kallon S; Kwakye GF
    Neurotoxicology; 2017 May; 60():54-69. PubMed ID: 28300621
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Defective Mitochondrial Dynamics and Protein Degradation Pathways Underlie Cadmium-Induced Neurotoxicity and Cell Death in Huntington's Disease Striatal Cells.
    Kamitsuka PJ; Ghanem MM; Ziar R; McDonald SE; Thomas MG; Kwakye GF
    Int J Mol Sci; 2023 Apr; 24(8):. PubMed ID: 37108341
    [TBL] [Abstract][Full Text] [Related]  

  • 4. α-Synuclein Enhances Cadmium Uptake and Neurotoxicity via Oxidative Stress and Caspase Activated Cell Death Mechanisms in a Dopaminergic Cell Model of Parkinson's Disease.
    Chong W; Jiménez J; McIIvin M; Saito MA; Kwakye GF
    Neurotox Res; 2017 Aug; 32(2):231-246. PubMed ID: 28353032
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Vanadium induces dopaminergic neurotoxicity via protein kinase Cdelta dependent oxidative signaling mechanisms: relevance to etiopathogenesis of Parkinson's disease.
    Afeseh Ngwa H; Kanthasamy A; Anantharam V; Song C; Witte T; Houk R; Kanthasamy AG
    Toxicol Appl Pharmacol; 2009 Oct; 240(2):273-85. PubMed ID: 19646462
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease.
    Ju TC; Chen HM; Chen YC; Chang CP; Chang C; Chern Y
    Biochim Biophys Acta; 2014 Sep; 1842(9):1668-80. PubMed ID: 24946181
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system.
    Williams BB; Kwakye GF; Wegrzynowicz M; Li D; Aschner M; Erikson KM; Bowman AB
    Toxicol Sci; 2010 Sep; 117(1):169-79. PubMed ID: 20547568
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chronic low-dose oxidative stress induces caspase-3-dependent PKCdelta proteolytic activation and apoptosis in a cell culture model of dopaminergic neurodegeneration.
    Carvour M; Song C; Kaul S; Anantharam V; Kanthasamy A; Kanthasamy A
    Ann N Y Acad Sci; 2008 Oct; 1139():197-205. PubMed ID: 18991865
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cadmium-induced apoptosis in murine macrophages is antagonized by antioxidants and caspase inhibitors.
    Kim J; Sharma RP
    J Toxicol Environ Health A; 2006 Jun; 69(12):1181-201. PubMed ID: 16728380
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cadmium-induced heme-oxygenase-1 expression plays dual roles in autophagy and apoptosis and is regulated by both PKC-δ and PKB/Akt activation in NRK52E kidney cells.
    So KY; Oh SH
    Toxicology; 2016 Aug; 370():49-59. PubMed ID: 27658547
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FGF9 induces neurite outgrowth upon ERK signaling in knock-in striatal Huntington's disease cells.
    Yusuf IO; Chen HM; Cheng PH; Chang CY; Tsai SJ; Chuang JI; Wu CC; Huang BM; Sun HS; Chen CM; Yang SH
    Life Sci; 2021 Feb; 267():118952. PubMed ID: 33383048
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glutathione redox cycle dysregulation in Huntington's disease knock-in striatal cells.
    Ribeiro M; Rosenstock TR; Cunha-Oliveira T; Ferreira IL; Oliveira CR; Rego AC
    Free Radic Biol Med; 2012 Nov; 53(10):1857-67. PubMed ID: 22982598
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dopaminergic signaling and striatal neurodegeneration in Huntington's disease.
    Tang TS; Chen X; Liu J; Bezprozvanny I
    J Neurosci; 2007 Jul; 27(30):7899-910. PubMed ID: 17652581
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington's disease.
    Berggren KL; Chen J; Fox J; Miller J; Dodds L; Dugas B; Vargas L; Lothian A; McAllum E; Volitakis I; Roberts B; Bush AI; Fox JH
    Redox Biol; 2015; 4():363-74. PubMed ID: 25703232
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitogen- and stress-activated protein kinase-1 deficiency is involved in expanded-huntingtin-induced transcriptional dysregulation and striatal death.
    Roze E; Betuing S; Deyts C; Marcon E; Brami-Cherrier K; Pagès C; Humbert S; Mérienne K; Caboche J
    FASEB J; 2008 Apr; 22(4):1083-93. PubMed ID: 18029446
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytotoxicity of paraquat in microglial cells: Involvement of PKCdelta- and ERK1/2-dependent NADPH oxidase.
    Miller RL; Sun GY; Sun AY
    Brain Res; 2007 Sep; 1167():129-39. PubMed ID: 17662968
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reduced Expression of Foxp1 as a Contributing Factor in Huntington's Disease.
    Louis Sam Titus ASC; Yusuff T; Cassar M; Thomas E; Kretzschmar D; D'Mello SR
    J Neurosci; 2017 Jul; 37(27):6575-6587. PubMed ID: 28550168
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GLP-1 Analogue Liraglutide Attenuates Mutant Huntingtin-Induced Neurotoxicity by Restoration of Neuronal Insulin Signaling.
    Chang CC; Lin TC; Ho HL; Kuo CY; Li HH; Korolenko TA; Chen WJ; Lai TJ; Ho YJ; Lin CL
    Int J Mol Sci; 2018 Aug; 19(9):. PubMed ID: 30149534
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cadmium-induced apoptosis through the mitochondrial pathway in rainbow trout hepatocytes: involvement of oxidative stress.
    Risso-de Faverney C; Orsini N; de Sousa G; Rahmani R
    Aquat Toxicol; 2004 Aug; 69(3):247-58. PubMed ID: 15276330
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events.
    Singh N; Lawana V; Luo J; Phong P; Abdalla A; Palanisamy B; Rokad D; Sarkar S; Jin H; Anantharam V; Kanthasamy AG; Kanthasamy A
    Neurobiol Dis; 2018 Sep; 117():82-113. PubMed ID: 29859868
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.