354 related articles for article (PubMed ID: 30401714)
1. Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis.
Yan X; Zhang X; Wang L; Zhang R; Pu X; Wu S; Li L; Tong P; Wang J; Meng QH; Jensen VB; Girard L; Minna JD; Roth JA; Swisher SG; Heymach JV; Fang B
Cancer Res; 2019 Jan; 79(1):125-132. PubMed ID: 30401714
[TBL] [Abstract][Full Text] [Related]
2. GSR is not essential for the maintenance of antioxidant defenses in mouse cochlea: Possible role of the thioredoxin system as a functional backup for GSR.
Han C; Kim MJ; Ding D; Park HJ; White K; Walker L; Gu T; Tanokura M; Yamasoba T; Linser P; Salvi R; Someya S
PLoS One; 2017; 12(7):e0180817. PubMed ID: 28686716
[TBL] [Abstract][Full Text] [Related]
3. Auranofin-mediated inhibition of PI3K/AKT/mTOR axis and anticancer activity in non-small cell lung cancer cells.
Li H; Hu J; Wu S; Wang L; Cao X; Zhang X; Dai B; Cao M; Shao R; Zhang R; Majidi M; Ji L; Heymach JV; Wang M; Pan S; Minna J; Mehran RJ; Swisher SG; Roth JA; Fang B
Oncotarget; 2016 Jan; 7(3):3548-58. PubMed ID: 26657290
[TBL] [Abstract][Full Text] [Related]
4. KEAP1-dependent synthetic lethality induced by AKT and TXNRD1 inhibitors in lung cancer.
Dai B; Yoo SY; Bartholomeusz G; Graham RA; Majidi M; Yan S; Meng J; Ji L; Coombes K; Minna JD; Fang B; Roth JA
Cancer Res; 2013 Sep; 73(17):5532-43. PubMed ID: 23824739
[TBL] [Abstract][Full Text] [Related]
5. Methionine restriction exposes a targetable redox vulnerability of triple-negative breast cancer cells by inducing thioredoxin reductase.
Malin D; Lee Y; Chepikova O; Strekalova E; Carlson A; Cryns VL
Breast Cancer Res Treat; 2021 Dec; 190(3):373-387. PubMed ID: 34553295
[TBL] [Abstract][Full Text] [Related]
6. Dual pharmacological inhibition of glutathione and thioredoxin systems synergizes to kill colorectal carcinoma stem cells.
Tanaka G; Inoue K; Shimizu T; Akimoto K; Kubota K
Cancer Med; 2016 Sep; 5(9):2544-57. PubMed ID: 27485632
[TBL] [Abstract][Full Text] [Related]
7. Enhancement of Radiation Response in Breast Cancer Stem Cells by Inhibition of Thioredoxin- and Glutathione-Dependent Metabolism.
Rodman SN; Spence JM; Ronnfeldt TJ; Zhu Y; Solst SR; O'Neill RA; Allen BG; Guan X; Spitz DR; Fath MA
Radiat Res; 2016 Oct; 186(4):385-395. PubMed ID: 27643875
[TBL] [Abstract][Full Text] [Related]
8. Simultaneous inhibition of glutathione- and thioredoxin-dependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress.
Scarbrough PM; Mapuskar KA; Mattson DM; Gius D; Watson WH; Spitz DR
Free Radic Biol Med; 2012 Jan; 52(2):436-43. PubMed ID: 22100505
[TBL] [Abstract][Full Text] [Related]
9. The Thioredoxin Reductase Inhibitor Auranofin Suppresses Pulmonary Metastasis of Osteosarcoma, But Not Local Progression.
Kinoshita H; Shimozato O; Ishii T; Kamoda H; Hagiwara Y; Tsukanishi T; Ohtori S; Yonemoto T
Anticancer Res; 2021 Oct; 41(10):4947-4955. PubMed ID: 34593442
[TBL] [Abstract][Full Text] [Related]
10. Glutathione reductase (
Baity M; Wang L; Correa AM; Zhang X; Zhang R; Pataer A; Wu S; Meng QH; Antonoff MB; Hofstetter WL; Mehran RJ; Rice DC; Roth JA; Sepesi B; Swisher SG; Vaporciyan AA; Walsh GL; Zhao M; Gu J; Fang B
Am J Cancer Res; 2019; 9(6):1201-1211. PubMed ID: 31285952
[TBL] [Abstract][Full Text] [Related]
11. Susceptibility of human head and neck cancer cells to combined inhibition of glutathione and thioredoxin metabolism.
Sobhakumari A; Love-Homan L; Fletcher EV; Martin SM; Parsons AD; Spitz DR; Knudson CM; Simons AL
PLoS One; 2012; 7(10):e48175. PubMed ID: 23118946
[TBL] [Abstract][Full Text] [Related]
12. The subunits of glutamate cysteine ligase enhance cisplatin resistance in human non-small cell lung cancer xenografts in vivo.
Fujimori S; Abe Y; Nishi M; Hamamoto A; Inoue Y; Ohnishi Y; Nishime C; Matsumoto H; Yamazaki H; Kijima H; Ueyama Y; Inoue H; Nakamura M
Int J Oncol; 2004 Aug; 25(2):413-8. PubMed ID: 15254739
[TBL] [Abstract][Full Text] [Related]
13. Epigallocatechin-3-gallate enhances key enzymatic activities of hepatic thioredoxin and glutathione systems in selenium-optimal mice but activates hepatic Nrf2 responses in selenium-deficient mice.
Dong R; Wang D; Wang X; Zhang K; Chen P; Yang CS; Zhang J
Redox Biol; 2016 Dec; 10():221-232. PubMed ID: 27810737
[TBL] [Abstract][Full Text] [Related]
14. Targeting of the Glutathione, Thioredoxin, and Nrf2 Antioxidant Systems in Head and Neck Cancer.
Roh JL; Jang H; Kim EH; Shin D
Antioxid Redox Signal; 2017 Jul; 27(2):106-114. PubMed ID: 27733046
[TBL] [Abstract][Full Text] [Related]
15. Non-reciprocal regulation of the redox state of the glutathione-glutaredoxin and thioredoxin systems.
Trotter EW; Grant CM
EMBO Rep; 2003 Feb; 4(2):184-8. PubMed ID: 12612609
[TBL] [Abstract][Full Text] [Related]
16. Dual targeting of the thioredoxin and glutathione antioxidant systems in malignant B cells: a novel synergistic therapeutic approach.
Kiebala M; Skalska J; Casulo C; Brookes PS; Peterson DR; Hilchey SP; Dai Y; Grant S; Maggirwar SB; Bernstein SH
Exp Hematol; 2015 Feb; 43(2):89-99. PubMed ID: 25448488
[TBL] [Abstract][Full Text] [Related]
17. Glutathione reductase mediates drug resistance in glioblastoma cells by regulating redox homeostasis.
Zhu Z; Du S; Du Y; Ren J; Ying G; Yan Z
J Neurochem; 2018 Jan; 144(1):93-104. PubMed ID: 29105080
[TBL] [Abstract][Full Text] [Related]
18. X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action.
Parsonage D; Sheng F; Hirata K; Debnath A; McKerrow JH; Reed SL; Abagyan R; Poole LB; Podust LM
J Struct Biol; 2016 May; 194(2):180-90. PubMed ID: 26876147
[TBL] [Abstract][Full Text] [Related]
19. Glutathione reductase gsr-1 is an essential gene required for Caenorhabditis elegans early embryonic development.
Mora-Lorca JA; Sáenz-Narciso B; Gaffney CJ; Naranjo-Galindo FJ; Pedrajas JR; Guerrero-Gómez D; Dobrzynska A; Askjaer P; Szewczyk NJ; Cabello J; Miranda-Vizuete A
Free Radic Biol Med; 2016 Jul; 96():446-61. PubMed ID: 27117030
[TBL] [Abstract][Full Text] [Related]
20. Methylglyoxal-Induced Protection Response and Toxicity: Role of Glutathione Reductase and Thioredoxin Systems.
Schmitz AE; de Souza LF; Dos Santos B; Maher P; Lopes FM; Londero GF; Klamt F; Dafre AL
Neurotox Res; 2017 Oct; 32(3):340-350. PubMed ID: 28478530
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]