BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

303 related articles for article (PubMed ID: 30404068)

  • 1. Inhibition of mTORC2/RICTOR Impairs Melanoma Hepatic Metastasis.
    Schmidt KM; Dietrich P; Hackl C; Guenzle J; Bronsert P; Wagner C; Fichtner-Feigl S; Schlitt HJ; Geissler EK; Hellerbrand C; Lang SA
    Neoplasia; 2018 Dec; 20(12):1198-1208. PubMed ID: 30404068
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
    Morrison Joly M; Williams MM; Hicks DJ; Jones B; Sanchez V; Young CD; Sarbassov DD; Muller WJ; Brantley-Sieders D; Cook RS
    Breast Cancer Res; 2017 Jun; 19(1):74. PubMed ID: 28666462
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rictor regulates the vasculogenic mimicry of melanoma via the AKT-MMP-2/9 pathway.
    Liang X; Sun R; Zhao X; Zhang Y; Gu Q; Dong X; Zhang D; Sun J; Sun B
    J Cell Mol Med; 2017 Dec; 21(12):3579-3591. PubMed ID: 28699701
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of mTORC2 component RICTOR impairs tumor growth in pancreatic cancer models.
    Schmidt KM; Hellerbrand C; Ruemmele P; Michalski CW; Kong B; Kroemer A; Hackl C; Schlitt HJ; Geissler EK; Lang SA
    Oncotarget; 2017 Apr; 8(15):24491-24505. PubMed ID: 28445935
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Down-regulation of Rictor enhances cell sensitivity to PI3K inhibitor LY294002 by blocking mTORC2-medicated phosphorylation of Akt/PRAS40 in esophageal squamous cell carcinoma.
    Hou G; Zhao Q; Zhang M; Fan T; Liu M; Shi X; Ren Y; Wang Y; Zhou J; Lu Z
    Biomed Pharmacother; 2018 Oct; 106():1348-1356. PubMed ID: 30119206
    [TBL] [Abstract][Full Text] [Related]  

  • 6. mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma.
    Holmes B; Benavides-Serrato A; Freeman RS; Landon KA; Bashir T; Nishimura RN; Gera J
    Oncogene; 2018 Feb; 37(6):732-743. PubMed ID: 29059166
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RICTOR/mTORC2 downregulation in BRAF
    Ponzone L; Audrito V; Landi C; Moiso E; Levra Levron C; Ferrua S; Savino A; Vitale N; Gasparrini M; Avalle L; Vantaggiato L; Shaba E; Tassone B; Saoncella S; Orso F; Viavattene D; Marina E; Fiorilla I; Burrone G; Abili Y; Altruda F; Bini L; Deaglio S; Defilippi P; Menga A; Poli V; Porporato PE; Provero P; Raffaelli N; Riganti C; Taverna D; Cavallo F; Calautti E
    Mol Cancer; 2024 May; 23(1):105. PubMed ID: 38755661
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential roles and activation of mammalian target of rapamycin complexes 1 and 2 during cell migration in prostate cancer cells.
    Venugopal SV; Caggia S; Gambrell-Sanders D; Khan SA
    Prostate; 2020 Apr; 80(5):412-423. PubMed ID: 31995655
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition.
    Ruicci KM; Plantinga P; Pinto N; Khan MI; Stecho W; Dhaliwal SS; Yoo J; Fung K; MacNeil D; Mymryk JS; Barrett JW; Howlett CJ; Nichols AC
    Mol Oncol; 2019 Oct; 13(10):2160-2177. PubMed ID: 31393061
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual inhibition of the PI3K/AKT/mTOR pathway suppresses the growth of leiomyosarcomas but leads to ERK activation through mTORC2: biological and clinical implications.
    Fourneaux B; Chaire V; Lucchesi C; Karanian M; Pineau R; Laroche-Clary A; Italiano A
    Oncotarget; 2017 Jan; 8(5):7878-7890. PubMed ID: 28002802
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MFN2 suppresses cancer progression through inhibition of mTORC2/Akt signaling.
    Xu K; Chen G; Li X; Wu X; Chang Z; Xu J; Zhu Y; Yin P; Liang X; Dong L
    Sci Rep; 2017 Feb; 7():41718. PubMed ID: 28176801
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Quantitative Proteomics Implicates Rictor/mTORC2 in Cell Adhesion.
    Wang H; Shao X; He Q; Wang C; Xia L; Yue D; Qin G; Jia C; Chen R
    J Proteome Res; 2018 Oct; 17(10):3360-3369. PubMed ID: 30156101
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TELO2 induced progression of colorectal cancer by binding with RICTOR through mTORC2.
    Guo Z; Zhang X; Zhu H; Zhong N; Luo X; Zhang Y; Tu F; Zhong J; Wang X; He J; Huang L
    Oncol Rep; 2021 Feb; 45(2):523-534. PubMed ID: 33416177
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased Levels of Rictor Prevent Mutant Huntingtin-Induced Neuronal Degeneration.
    Creus-Muncunill J; Rué L; Alcalá-Vida R; Badillos-Rodríguez R; Romaní-Aumedes J; Marco S; Alberch J; Perez-Otaño I; Malagelada C; Pérez-Navarro E
    Mol Neurobiol; 2018 Oct; 55(10):7728-7742. PubMed ID: 29460266
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rictor/mTORC2 involves mitochondrial function in ES cells derived cardiomyocytes via mitochondrial Connexin 43.
    Wang JD; Shao Y; Liu D; Liu NY; Zhu DY
    Acta Pharmacol Sin; 2021 Nov; 42(11):1790-1797. PubMed ID: 33547375
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Two conserved glycine residues in mammalian and
    Pergolizzi B; Panuzzo C; Ali MS; Lo Iacono M; Levra Levron C; Ponzone L; Prelli M; Cilloni D; Calautti E; Bozzaro S; Bracco E
    J Cell Sci; 2019 Nov; 132(22):. PubMed ID: 31653780
    [TBL] [Abstract][Full Text] [Related]  

  • 17. mTORC2/Rictor is essential for coelomocyte endocytosis in Apostichopus japonicus.
    Lv Z; Yue Z; Shao Y; Li C; Zhao X; Guo M
    Dev Comp Immunol; 2021 May; 118():104000. PubMed ID: 33444645
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Unmasking the impact of Rictor in cancer: novel insights of mTORC2 complex.
    Gkountakos A; Pilotto S; Mafficini A; Vicentini C; Simbolo M; Milella M; Tortora G; Scarpa A; Bria E; Corbo V
    Carcinogenesis; 2018 Jul; 39(8):971-980. PubMed ID: 29955840
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rapamycin-insensitive companion of mTOR (RICTOR) amplification defines a subset of advanced gastric cancer and is sensitive to AZD2014-mediated mTORC1/2 inhibition.
    Kim ST; Kim SY; Klempner SJ; Yoon J; Kim N; Ahn S; Bang H; Kim KM; Park W; Park SH; Park JO; Park YS; Lim HY; Lee SH; Park K; Kang WK; Lee J
    Ann Oncol; 2017 Mar; 28(3):547-554. PubMed ID: 28028034
    [TBL] [Abstract][Full Text] [Related]  

  • 20. mTORC2 negatively controls the maturation process of medullary thymic epithelial cells by inhibiting the LTβR/RANK-NF-κB axis.
    Liang Z; Zhang Q; Dong X; Zhang Z; Wang H; Zhang J; Zhao Y
    J Cell Physiol; 2021 Jun; 236(6):4725-4737. PubMed ID: 33269476
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.