BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

464 related articles for article (PubMed ID: 30404819)

  • 1. Phosphorylation of Parkin at serine 65 is essential for its activation
    McWilliams TG; Barini E; Pohjolan-Pirhonen R; Brooks SP; Singh F; Burel S; Balk K; Kumar A; Montava-Garriga L; Prescott AR; Hassoun SM; Mouton-Liger F; Ball G; Hills R; Knebel A; Ulusoy A; Di Monte DA; Tamjar J; Antico O; Fears K; Smith L; Brambilla R; Palin E; Valori M; Eerola-Rautio J; Tienari P; Corti O; Dunnett SB; Ganley IG; Suomalainen A; Muqit MMK
    Open Biol; 2018 Nov; 8(11):. PubMed ID: 30404819
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.
    Kazlauskaite A; Kondapalli C; Gourlay R; Campbell DG; Ritorto MS; Hofmann K; Alessi DR; Knebel A; Trost M; Muqit MM
    Biochem J; 2014 May; 460(1):127-39. PubMed ID: 24660806
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.
    Kazlauskaite A; Martínez-Torres RJ; Wilkie S; Kumar A; Peltier J; Gonzalez A; Johnson C; Zhang J; Hope AG; Peggie M; Trost M; van Aalten DM; Alessi DR; Prescott AR; Knebel A; Walden H; Muqit MM
    EMBO Rep; 2015 Aug; 16(8):939-54. PubMed ID: 26116755
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy.
    Shiba-Fukushima K; Imai Y; Yoshida S; Ishihama Y; Kanao T; Sato S; Hattori N
    Sci Rep; 2012; 2():1002. PubMed ID: 23256036
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nix restores mitophagy and mitochondrial function to protect against PINK1/Parkin-related Parkinson's disease.
    Koentjoro B; Park JS; Sue CM
    Sci Rep; 2017 Mar; 7():44373. PubMed ID: 28281653
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models.
    Martinez A; Sanchez-Martinez A; Pickering JT; Twyning MJ; Terriente-Felix A; Chen PL; Chen CH; Whitworth AJ
    Mol Neurodegener; 2024 Jan; 19(1):12. PubMed ID: 38273330
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LRRK2 impairs PINK1/Parkin-dependent mitophagy via its kinase activity: pathologic insights into Parkinson's disease.
    Bonello F; Hassoun SM; Mouton-Liger F; Shin YS; Muscat A; Tesson C; Lesage S; Beart PM; Brice A; Krupp J; Corvol JC; Corti O
    Hum Mol Genet; 2019 May; 28(10):1645-1660. PubMed ID: 30629163
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy.
    Ordureau A; Heo JM; Duda DM; Paulo JA; Olszewski JL; Yanishevski D; Rinehart J; Schulman BA; Harper JW
    Proc Natl Acad Sci U S A; 2015 May; 112(21):6637-42. PubMed ID: 25969509
    [TBL] [Abstract][Full Text] [Related]  

  • 9. N-degron-mediated degradation and regulation of mitochondrial PINK1 kinase.
    Eldeeb MA; Ragheb MA
    Curr Genet; 2020 Aug; 66(4):693-701. PubMed ID: 32157382
    [TBL] [Abstract][Full Text] [Related]  

  • 10. S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models.
    Oh CK; Sultan A; Platzer J; Dolatabadi N; Soldner F; McClatchy DB; Diedrich JK; Yates JR; Ambasudhan R; Nakamura T; Jaenisch R; Lipton SA
    Cell Rep; 2017 Nov; 21(8):2171-2182. PubMed ID: 29166608
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications.
    Durcan TM; Fon EA
    Genes Dev; 2015 May; 29(10):989-99. PubMed ID: 25995186
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nitric oxide induction of Parkin translocation in PTEN-induced putative kinase 1 (PINK1) deficiency: functional role of neuronal nitric oxide synthase during mitophagy.
    Han JY; Kang MJ; Kim KH; Han PL; Kim HS; Ha JY; Son JH
    J Biol Chem; 2015 Apr; 290(16):10325-35. PubMed ID: 25716315
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation by mitophagy.
    Hattori N; Saiki S; Imai Y
    Int J Biochem Cell Biol; 2014 Aug; 53():147-50. PubMed ID: 24842103
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy.
    Imberechts D; Kinnart I; Wauters F; Terbeek J; Manders L; Wierda K; Eggermont K; Madeiro RF; Sue C; Verfaillie C; Vandenberghe W
    Brain; 2022 Dec; 145(12):4368-4384. PubMed ID: 36039535
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The PINK1, synphilin-1 and SIAH-1 complex constitutes a novel mitophagy pathway.
    Szargel R; Shani V; Abd Elghani F; Mekies LN; Liani E; Rott R; Engelender S
    Hum Mol Genet; 2016 Aug; 25(16):3476-3490. PubMed ID: 27334109
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PINK1/PARKIN signalling in neurodegeneration and neuroinflammation.
    Quinn PMJ; Moreira PI; Ambrósio AF; Alves CH
    Acta Neuropathol Commun; 2020 Nov; 8(1):189. PubMed ID: 33168089
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations.
    Geisler S; Holmström KM; Treis A; Skujat D; Weber SS; Fiesel FC; Kahle PJ; Springer W
    Autophagy; 2010 Oct; 6(7):871-8. PubMed ID: 20798600
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PINK1 and Parkin: team players in stress-induced mitophagy.
    Bader V; Winklhofer KF
    Biol Chem; 2020 May; 401(6-7):891-899. PubMed ID: 32297878
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PINK1/Parkin mitophagy and neurodegeneration-what do we really know in vivo?
    Whitworth AJ; Pallanck LJ
    Curr Opin Genet Dev; 2017 Jun; 44():47-53. PubMed ID: 28213158
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Parkin recruitment to impaired mitochondria for nonselective ubiquitylation is facilitated by MITOL.
    Koyano F; Yamano K; Kosako H; Tanaka K; Matsuda N
    J Biol Chem; 2019 Jun; 294(26):10300-10314. PubMed ID: 31110043
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 24.