BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

284 related articles for article (PubMed ID: 30405628)

  • 1. Pharmacological Inhibition of Toll-Like Receptor-4 Signaling by TAK242 Prevents and Induces Regression of Experimental Organ Fibrosis.
    Bhattacharyya S; Wang W; Tamaki Z; Shi B; Yeldandi A; Tsukimi Y; Yamasaki M; Varga J
    Front Immunol; 2018; 9():2434. PubMed ID: 30405628
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Amelioration of tissue fibrosis by toll-like receptor 4 knockout in murine models of systemic sclerosis.
    Takahashi T; Asano Y; Ichimura Y; Toyama T; Taniguchi T; Noda S; Akamata K; Tada Y; Sugaya M; Kadono T; Sato S
    Arthritis Rheumatol; 2015 Jan; 67(1):254-65. PubMed ID: 25302613
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TLR4-dependent fibroblast activation drives persistent organ fibrosis in skin and lung.
    Bhattacharyya S; Wang W; Qin W; Cheng K; Coulup S; Chavez S; Jiang S; Raparia K; De Almeida LMV; Stehlik C; Tamaki Z; Yin H; Varga J
    JCI Insight; 2018 Jul; 3(13):. PubMed ID: 29997297
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma.
    Bhattacharyya S; Kelley K; Melichian DS; Tamaki Z; Fang F; Su Y; Feng G; Pope RM; Budinger GR; Mutlu GM; Lafyatis R; Radstake T; Feghali-Bostwick C; Varga J
    Am J Pathol; 2013 Jan; 182(1):192-205. PubMed ID: 23141927
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A profibrotic role for thymic stromal lymphopoietin in systemic sclerosis.
    Usategui A; Criado G; Izquierdo E; Del Rey MJ; Carreira PE; Ortiz P; Leonard WJ; Pablos JL
    Ann Rheum Dis; 2013 Dec; 72(12):2018-23. PubMed ID: 23413283
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacological inhibition of TAK1 prevents and induces regression of experimental organ fibrosis.
    Bale S; Verma P; Yalavarthi B; Scarneo SA; Hughes P; Amin MA; Tsou PS; Khanna D; Haystead TA; Bhattacharyya S; Varga J
    JCI Insight; 2023 Jul; 8(14):. PubMed ID: 37306632
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis.
    Tomcik M; Zerr P; Pitkowski J; Palumbo-Zerr K; Avouac J; Distler O; Becvar R; Senolt L; Schett G; Distler JH
    Ann Rheum Dis; 2014 Jun; 73(6):1215-22. PubMed ID: 23661493
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tenascin-C drives persistence of organ fibrosis.
    Bhattacharyya S; Wang W; Morales-Nebreda L; Feng G; Wu M; Zhou X; Lafyatis R; Lee J; Hinchcliff M; Feghali-Bostwick C; Lakota K; Budinger GR; Raparia K; Tamaki Z; Varga J
    Nat Commun; 2016 Jun; 7():11703. PubMed ID: 27256716
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Toll-like Receptor 9 Signaling Is Augmented in Systemic Sclerosis and Elicits Transforming Growth Factor β-Dependent Fibroblast Activation.
    Fang F; Marangoni RG; Zhou X; Yang Y; Ye B; Shangguang A; Qin W; Wang W; Bhattacharyya S; Wei J; Tourtellotte WG; Varga J
    Arthritis Rheumatol; 2016 Aug; 68(8):1989-2002. PubMed ID: 26946325
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Blockade of CCL24 with a monoclonal antibody ameliorates experimental dermal and pulmonary fibrosis.
    Mor A; Segal Salto M; Katav A; Barashi N; Edelshtein V; Manetti M; Levi Y; George J; Matucci-Cerinic M
    Ann Rheum Dis; 2019 Sep; 78(9):1260-1268. PubMed ID: 31129606
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FibronectinEDA promotes chronic cutaneous fibrosis through Toll-like receptor signaling.
    Bhattacharyya S; Tamaki Z; Wang W; Hinchcliff M; Hoover P; Getsios S; White ES; Varga J
    Sci Transl Med; 2014 Apr; 6(232):232ra50. PubMed ID: 24739758
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Th17 cells and IL-17 promote the skin and lung inflammation and fibrosis process in a bleomycin-induced murine model of systemic sclerosis.
    Lei L; Zhao C; Qin F; He ZY; Wang X; Zhong XN
    Clin Exp Rheumatol; 2016; 34 Suppl 100(5):14-22. PubMed ID: 26750756
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis.
    Avouac J; Palumbo-Zerr K; Ruzehaji N; Tomcik M; Zerr P; Dees C; Distler A; Beyer C; Schneider H; Distler O; Schett G; Allanore Y; Distler JH
    Arthritis Rheumatol; 2014 Nov; 66(11):3140-50. PubMed ID: 25155144
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc.
    Liang R; Šumová B; Cordazzo C; Mallano T; Zhang Y; Wohlfahrt T; Dees C; Ramming A; Krasowska D; Michalska-Jakubus M; Distler O; Schett G; Šenolt L; Distler JH
    Ann Rheum Dis; 2017 Apr; 76(4):756-764. PubMed ID: 27793816
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis.
    Zhang Y; Dees C; Beyer C; Lin NY; Distler A; Zerr P; Palumbo K; Susok L; Kreuter A; Distler O; Schett G; Distler JH
    Ann Rheum Dis; 2015 May; 74(5):936-43. PubMed ID: 24431397
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Elevated frequencies of CD4(+) IL-21(+) T, CD4(+) IL-21R(+) T and IL-21(+) Th17 cells, and increased levels of IL-21 in bleomycin-induced mice may be associated with dermal and pulmonary inflammation and fibrosis.
    Lei L; He ZY; Zhao C; Sun XJ; Zhong XN
    Int J Rheum Dis; 2016 Apr; 19(4):392-404. PubMed ID: 25545680
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vivo investigations on anti-fibrotic potential of proteasome inhibition in lung and skin fibrosis.
    Fineschi S; Bongiovanni M; Donati Y; Djaafar S; Naso F; Goffin L; Argiroffo CB; Pache JC; Dayer JM; Ferrari-Lacraz S; Chizzolini C
    Am J Respir Cell Mol Biol; 2008 Oct; 39(4):458-65. PubMed ID: 18458239
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ATRA ameliorates fibrosis by suppressing the pro-fibrotic molecule Fra2/AP-1 in systemic sclerosis.
    Pi Z; Liu J; Xiao Y; He X; Zhu R; Tang R; Qiu X; Zhan Y; Zeng Z; Shi Y; Xiao R
    Int Immunopharmacol; 2023 Aug; 121():110420. PubMed ID: 37331293
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma?
    Wei J; Melichian D; Komura K; Hinchcliff M; Lam AP; Lafyatis R; Gottardi CJ; MacDougald OA; Varga J
    Arthritis Rheum; 2011 Jun; 63(6):1707-17. PubMed ID: 21370225
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A synthetic PPAR-γ agonist triterpenoid ameliorates experimental fibrosis: PPAR-γ-independent suppression of fibrotic responses.
    Wei J; Zhu H; Komura K; Lord G; Tomcik M; Wang W; Doniparthi S; Tamaki Z; Hinchcliff M; Distler JH; Varga J
    Ann Rheum Dis; 2014 Feb; 73(2):446-54. PubMed ID: 23515440
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.