These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
8. Mutation-dependent aggregation and toxicity in a Drosophila model for UBQLN2-associated ALS. Kim SH; Stiles SG; Feichtmeier JM; Ramesh N; Zhan L; Scalf MA; Smith LM; Pandey UB; Tibbetts RS Hum Mol Genet; 2018 Jan; 27(2):322-337. PubMed ID: 29161404 [TBL] [Abstract][Full Text] [Related]
9. Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations. Le NT; Chang L; Kovlyagina I; Georgiou P; Safren N; Braunstein KE; Kvarta MD; Van Dyke AM; LeGates TA; Philips T; Morrison BM; Thompson SM; Puche AC; Gould TD; Rothstein JD; Wong PC; Monteiro MJ Proc Natl Acad Sci U S A; 2016 Nov; 113(47):E7580-E7589. PubMed ID: 27834214 [TBL] [Abstract][Full Text] [Related]
10. Spinal inhibitory interneuron pathology follows motor neuron degeneration independent of glial mutant superoxide dismutase 1 expression in SOD1-ALS mice. Hossaini M; Cardona Cano S; van Dis V; Haasdijk ED; Hoogenraad CC; Holstege JC; Jaarsma D J Neuropathol Exp Neurol; 2011 Aug; 70(8):662-77. PubMed ID: 21760539 [TBL] [Abstract][Full Text] [Related]
11. Damaged DNA Is an Early Event of Neurodegeneration in Induced Pluripotent Stem Cell-Derived Motoneurons with UBQLN2 Zhang Y; Zeng B; Gu A; Kang Q; Zhao M; Peng G; Zhou M; Liu W; Liu M; Ding L; Liang D; Liu X; Liu M Int J Mol Sci; 2022 Sep; 23(19):. PubMed ID: 36232630 [No Abstract] [Full Text] [Related]
12. Mutant TDP-43 in motor neurons promotes the onset and progression of ALS in rats. Huang C; Tong J; Bi F; Zhou H; Xia XG J Clin Invest; 2012 Jan; 122(1):107-18. PubMed ID: 22156203 [TBL] [Abstract][Full Text] [Related]
13. A robust TDP-43 knock-in mouse model of ALS. Huang SL; Wu LS; Lee M; Chang CW; Cheng WC; Fang YS; Chen YR; Cheng PL; Shen CJ Acta Neuropathol Commun; 2020 Jan; 8(1):3. PubMed ID: 31964415 [TBL] [Abstract][Full Text] [Related]
14. Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Deng HX; Chen W; Hong ST; Boycott KM; Gorrie GH; Siddique N; Yang Y; Fecto F; Shi Y; Zhai H; Jiang H; Hirano M; Rampersaud E; Jansen GH; Donkervoort S; Bigio EH; Brooks BR; Ajroud K; Sufit RL; Haines JL; Mugnaini E; Pericak-Vance MA; Siddique T Nature; 2011 Aug; 477(7363):211-5. PubMed ID: 21857683 [TBL] [Abstract][Full Text] [Related]
15. Mutant PFN1 causes ALS phenotypes and progressive motor neuron degeneration in mice by a gain of toxicity. Yang C; Danielson EW; Qiao T; Metterville J; Brown RH; Landers JE; Xu Z Proc Natl Acad Sci U S A; 2016 Oct; 113(41):E6209-E6218. PubMed ID: 27681617 [TBL] [Abstract][Full Text] [Related]
16. Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons. Castillo K; Nassif M; Valenzuela V; Rojas F; Matus S; Mercado G; Court FA; van Zundert B; Hetz C Autophagy; 2013 Sep; 9(9):1308-20. PubMed ID: 23851366 [TBL] [Abstract][Full Text] [Related]
17. Disturbance of proteasomal and autophagic protein degradation pathways by amyotrophic lateral sclerosis-linked mutations in ubiquilin 2. Osaka M; Ito D; Suzuki N Biochem Biophys Res Commun; 2016 Apr; 472(2):324-31. PubMed ID: 26944018 [TBL] [Abstract][Full Text] [Related]
18. ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function. Wu JJ; Cai A; Greenslade JE; Higgins NR; Fan C; Le NTT; Tatman M; Whiteley AM; Prado MA; Dieriks BV; Curtis MA; Shaw CE; Siddique T; Faull RLM; Scotter EL; Finley D; Monteiro MJ Proc Natl Acad Sci U S A; 2020 Jun; 117(26):15230-15241. PubMed ID: 32513711 [TBL] [Abstract][Full Text] [Related]
19. Impaired 26S Proteasome Assembly Precedes Neuronal Loss in Mutant UBQLN2 Rats. Zhang W; Huang B; Gao L; Huang C Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33919255 [TBL] [Abstract][Full Text] [Related]
20. Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis. Osaka M; Ito D; Yagi T; Nihei Y; Suzuki N Hum Mol Genet; 2015 Mar; 24(6):1617-29. PubMed ID: 25398946 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]