These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 30409834)

  • 1. Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol.
    Teitelbaum AM; McDonald MG; Kowalski JP; Parkinson OT; Scian M; Whittington D; Roellecke K; Hanenberg H; Wiek C; Rettie AE
    J Pharmacol Exp Ther; 2019 Feb; 368(2):308-316. PubMed ID: 30409834
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity.
    Parkinson OT; Teitelbaum AM; Whittington D; Kelly EJ; Rettie AE
    Drug Metab Dispos; 2016 Oct; 44(10):1598-602. PubMed ID: 27468999
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.
    Ma L; Sun J; Peng Y; Zhang R; Shao F; Hu X; Zhu J; Wang X; Cheng X; Zhu Y; Wan P; Feng D; Wu H; Wang G
    Drug Metab Dispos; 2012 Apr; 40(4):734-41. PubMed ID: 22238289
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Generation and characterization of a Cyp4b1 null mouse and the role of CYP4B1 in the activation and toxicity of Ipomeanol.
    Parkinson OT; Liggitt HD; Rettie AE; Kelly EJ
    Toxicol Sci; 2013 Aug; 134(2):243-50. PubMed ID: 23748241
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of human UDP-glucuronosyltransferases involved in N-carbamoyl glucuronidation of lorcaserin.
    Sadeque AJ; Usmani KA; Palamar S; Cerny MA; Chen WG
    Drug Metab Dispos; 2012 Apr; 40(4):772-8. PubMed ID: 22259019
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9.
    Court MH; Duan SX; Guillemette C; Journault K; Krishnaswamy S; Von Moltke LL; Greenblatt DJ
    Drug Metab Dispos; 2002 Nov; 30(11):1257-65. PubMed ID: 12386133
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform.
    Kaji H; Kume T
    Drug Metab Dispos; 2005 Mar; 33(3):403-12. PubMed ID: 15608137
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of amino acid determinants in CYP4B1 for optimal catalytic processing of 4-ipomeanol.
    Wiek C; Schmidt EM; Roellecke K; Freund M; Nakano M; Kelly EJ; Kaisers W; Yarov-Yarovoy V; Kramm CM; Rettie AE; Hanenberg H
    Biochem J; 2015 Jan; 465(1):103-14. PubMed ID: 25247810
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of benzo(a)pyrene-trans-7,8-dihydrodiol glucuronidation by human tissue microsomes and overexpressed UDP-glucuronosyltransferase enzymes.
    Fang JL; Beland FA; Doerge DR; Wiener D; Guillemette C; Marques MM; Lazarus P
    Cancer Res; 2002 Apr; 62(7):1978-86. PubMed ID: 11929814
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bioactivation of 4-ipomeanol by CYP4B1: adduct characterization and evidence for an enedial intermediate.
    Baer BR; Rettie AE; Henne KR
    Chem Res Toxicol; 2005 May; 18(5):855-64. PubMed ID: 15892579
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes.
    Yamanaka H; Nakajima M; Katoh M; Kanoh A; Tamura O; Ishibashi H; Yokoi T
    Drug Metab Dispos; 2005 Jan; 33(1):23-30. PubMed ID: 15470160
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Non-steroidal anti-inflammatory drugs interact with testosterone glucuronidation.
    Sten T; Finel M; Ask B; Rane A; Ekström L
    Steroids; 2009 Nov; 74(12):971-7. PubMed ID: 19643121
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glucuronidation of fenamates: kinetic studies using human kidney cortical microsomes and recombinant UDP-glucuronosyltransferase (UGT) 1A9 and 2B7.
    Gaganis P; Miners JO; Knights KM
    Biochem Pharmacol; 2007 May; 73(10):1683-91. PubMed ID: 17343829
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7.
    Innocenti F; Iyer L; Ramírez J; Green MD; Ratain MJ
    Drug Metab Dispos; 2001 May; 29(5):686-92. PubMed ID: 11302935
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-Activity Relationships for CYP4B1 Bioactivation of 4-Ipomeanol Congeners: Direct Correlation between Cytotoxicity and Trapped Reactive Intermediates.
    Kowalski JP; McDonald MG; Whittington D; Guttman M; Scian M; Girhard M; Hanenberg H; Wiek C; Rettie AE
    Chem Res Toxicol; 2019 Dec; 32(12):2488-2498. PubMed ID: 31799839
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stereoselective glucuronidation of propranolol in human and cynomolgus monkey liver microsomes: role of human hepatic UDP-glucuronosyltransferase isoforms, UGT1A9, UGT2B4 and UGT2B7.
    Hanioka N; Hayashi K; Shimizudani T; Nagaoka K; Koeda A; Naito S; Narimatsu S
    Pharmacology; 2008; 82(4):293-303. PubMed ID: 18936551
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stereoselective glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin by human UDP-glucuronosyltransferase (UGT) 1A1, UGT1A9, and UGT2B15: effects of UGT-UGT interactions.
    Nakajima M; Yamanaka H; Fujiwara R; Katoh M; Yokoi T
    Drug Metab Dispos; 2007 Sep; 35(9):1679-86. PubMed ID: 17576806
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver.
    Mano Y; Usui T; Kamimura H
    Drug Metab Dispos; 2007 Jul; 35(7):1182-7. PubMed ID: 17446261
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N-glucuronidation of nicotine and cotinine in human: formation of cotinine glucuronide in liver microsomes and lack of catalysis by 10 examined UDP-glucuronosyltransferases.
    Ghosheh O; Hawes EM
    Drug Metab Dispos; 2002 Sep; 30(9):991-6. PubMed ID: 12167564
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stereoselective glucuronidation of ornidazole in humans: predominant contribution of UDP-glucuronosyltransferases 1A9 and 2B7.
    Du J; You T; Chen X; Zhong D
    Drug Metab Dispos; 2013 Jul; 41(7):1306-18. PubMed ID: 23571427
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.