BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 30409980)

  • 1. FXR agonist obeticholic acid induces liver growth but exacerbates biliary injury in rats with obstructive cholestasis.
    van Golen RF; Olthof PB; Lionarons DA; Reiniers MJ; Alles LK; Uz Z; de Haan L; Ergin B; de Waart DR; Maas A; Verheij J; Jansen PL; Damink SWO; Schaap FG; van Gulik TM; Heger M
    Sci Rep; 2018 Nov; 8(1):16529. PubMed ID: 30409980
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Unaltered Liver Regeneration in Post-Cholestatic Rats Treated with the FXR Agonist Obeticholic Acid.
    de Haan LR; Verheij J; van Golen RF; Horneffer-van der Sluis V; Lewis MR; Beuers UHW; van Gulik TM; Olde Damink SWM; Schaap FG; Heger M; Olthof PB
    Biomolecules; 2021 Feb; 11(2):. PubMed ID: 33578971
    [No Abstract]   [Full Text] [Related]  

  • 3. Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis.
    Carino A; Biagioli M; Marchianò S; Fiorucci C; Bordoni M; Roselli R; Di Giorgio C; Baldoni M; Ricci P; Monti MC; Morretta E; Zampella A; Distrutti E; Fiorucci S
    Biochim Biophys Acta Mol Cell Biol Lipids; 2020 Sep; 1865(9):158733. PubMed ID: 32371093
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effect of obeticholic acid on liver regeneration following portal vein embolization in an experimental model.
    Olthof PB; Huisman F; Schaap FG; van Lienden KP; Bennink RJ; van Golen RF; Heger M; Verheij J; Jansen PL; Olde Damink SW; van Gulik TM
    Br J Surg; 2017 Apr; 104(5):590-599. PubMed ID: 28195307
    [TBL] [Abstract][Full Text] [Related]  

  • 5. miR-199a-5p inhibits the expression of ABCB11 in obstructive cholestasis.
    Balasubramaniyan N; Devereaux MW; Orlicky DJ; Sokol RJ; Suchy FJ
    J Biol Chem; 2021 Dec; 297(6):101400. PubMed ID: 34774795
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BRD4 inhibition and FXR activation, individually beneficial in cholestasis, are antagonistic in combination.
    Jung H; Chen J; Hu X; Sun H; Wu SY; Chiang CM; Kemper B; Chen LF; Kemper JK
    JCI Insight; 2020 Dec; 6(1):. PubMed ID: 33290278
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Obeticholic acid improves fetal bile acid profile in a mouse model of gestational hypercholanemia.
    Pataia V; McIlvride S; Papacleovoulou G; Ovadia C; McDonald JAK; Wahlström A; Jansen E; Adorini L; Shapiro D; Marchesi JR; Marschall HU; Williamson C
    Am J Physiol Gastrointest Liver Physiol; 2020 Aug; 319(2):G197-G211. PubMed ID: 32597707
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Obeticholic acid protects mice against lipopolysaccharide-induced liver injury and inflammation.
    Xiong X; Ren Y; Cui Y; Li R; Wang C; Zhang Y
    Biomed Pharmacother; 2017 Dec; 96():1292-1298. PubMed ID: 29174575
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gene expression profiling in human precision cut liver slices in response to the FXR agonist obeticholic acid.
    Ijssennagger N; Janssen AWF; Milona A; Ramos Pittol JM; Hollman DAA; Mokry M; Betzel B; Berends FJ; Janssen IM; van Mil SWC; Kersten S
    J Hepatol; 2016 May; 64(5):1158-1166. PubMed ID: 26812075
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis.
    Panzitt K; Jungwirth E; Krones E; Lee JM; Pollheimer M; Thallinger GG; Kolb-Lenz D; Xiao R; Thorell A; Trauner M; Fickert P; Marschall HU; Moore DD; Wagner M
    J Hepatol; 2020 Jun; 72(6):1122-1131. PubMed ID: 32001325
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Yangonin protects against cholestasis and hepatotoxity via activation of farnesoid X receptor in vivo and in vitro.
    Gao X; Fu T; Wang C; Ning C; Liu K; Liu Z; Sun H; Ma X; Huo X; Yang X; Zou M; Meng Q
    Toxicol Appl Pharmacol; 2018 Jun; 348():105-116. PubMed ID: 29660435
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Farnesoid X Receptor Agonist Treatment Alters Bile Acid Metabolism but Exacerbates Liver Damage in a Piglet Model of Short-Bowel Syndrome.
    Pereira-Fantini PM; Lapthorne S; Gahan CGM; Joyce SA; Charles J; Fuller PJ; Bines JE
    Cell Mol Gastroenterol Hepatol; 2017 Jul; 4(1):65-74. PubMed ID: 28560290
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Systemic ASBT inactivation protects against liver damage in obstructive cholestasis in mice.
    Kunst RF; de Waart DR; Wolters F; Duijst S; Vogels EW; Bolt I; Verheij J; Beuers U; Oude Elferink RPJ; van de Graaf SFJ
    JHEP Rep; 2022 Nov; 4(11):100573. PubMed ID: 36160754
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of Intestinal FXR-Related Molecules on Intestinal Mucosal Barriers in Biliary Tract Obstruction.
    Yan M; Hou L; Cai Y; Wang H; Ma Y; Geng Q; Jiang W; Tang W
    Front Pharmacol; 2022; 13():906452. PubMed ID: 35770078
    [No Abstract]   [Full Text] [Related]  

  • 15. Comparative potency of obeticholic acid and natural bile acids on FXR in hepatic and intestinal in vitro cell models.
    Zhang Y; LaCerte C; Kansra S; Jackson JP; Brouwer KR; Edwards JE
    Pharmacol Res Perspect; 2017 Dec; 5(6):. PubMed ID: 29226620
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Obeticholic acid protects against lithocholic acid-induced exogenous cell apoptosis during cholestatic liver injury.
    Lu Q; Zhu Y; Wang C; Zhang R; Miao Y; Chai Y; Jiang Z; Yu Q
    Life Sci; 2024 Jan; 337():122355. PubMed ID: 38104861
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Obeticholic acid improves hepatic bile acid excretion in patients with primary biliary cholangitis.
    Kjærgaard K; Frisch K; Sørensen M; Munk OL; Hofmann AF; Horsager J; Schacht AC; Erickson M; Shapiro D; Keiding S
    J Hepatol; 2021 Jan; 74(1):58-65. PubMed ID: 32717289
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Obeticholic acid may increase the risk of gallstone formation in susceptible patients.
    Al-Dury S; Wahlström A; Panzitt K; Thorell A; Ståhlman M; Trauner M; Fickert P; Bäckhed F; Fändriks L; Wagner M; Marschall HU
    J Hepatol; 2019 Nov; 71(5):986-991. PubMed ID: 31254596
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Picroside II protects against cholestatic liver injury possibly through activation of farnesoid X receptor.
    Li T; Xu L; Zheng R; Wang X; Li L; Ji H; Hu Q
    Phytomedicine; 2020 Mar; 68():153153. PubMed ID: 32018210
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice.
    Wagner M; Fickert P; Zollner G; Fuchsbichler A; Silbert D; Tsybrovskyy O; Zatloukal K; Guo GL; Schuetz JD; Gonzalez FJ; Marschall HU; Denk H; Trauner M
    Gastroenterology; 2003 Sep; 125(3):825-38. PubMed ID: 12949728
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.